AKIN criteria
Nephrology and urology
Also known as: AKIN-Stadien (akute Nierenschädigung) · AKIN evrelemesi · AKIN staging of acute kidney injury (Acute Kidney Injury Network 2007)
What it is for
AKIN defines acute kidney injury as an abrupt (within 48 hours) fall in kidney function: an absolute rise in serum creatinine (SCr) of ≥0.3 mg/dl (≥26.4 µmol/l), a rise of ≥50% (1.5-fold) from baseline, or oliguria <0.5 ml/kg/h for more than 6 hours, applied after adequate fluid status and exclusion of obstruction. One criterion (creatinine or urine output) suffices for a stage.
Classification
| Category | Description |
|---|---|
| Stage 1 | SCr rise ≥0.3 mg/dl (≥26.4 µmol/l) or to 150–200% (1.5- to 2-fold) of baseline; or urine output <0.5 ml/kg/h for more than 6 hours. |
| Stage 2 | SCr rise to more than 200–300% (>2- to 3-fold) of baseline; or urine output <0.5 ml/kg/h for more than 12 hours. |
| Stage 3 | SCr rise to more than 300% (>3-fold) of baseline, or SCr ≥4.0 mg/dl (≥354 µmol/l) with an acute rise of at least 0.5 mg/dl (44 µmol/l); or urine output <0.3 ml/kg/h for 24 hours, or anuria for 12 hours. Anyone receiving renal replacement therapy is stage 3. |
| Relation to RIFLE | Stages 1–3 correspond to RIFLE Risk, Injury and Failure; Loss and End-stage are outcomes, not stages, in AKIN. |
Source
Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury
Acute Kidney Injury Network · Crit Care 2007;11:R31 (Mehta RL et al.)
DOI: 10.1186/cc5713
PMID: 17331245
- Edition
- AKIN 2007; superseded for staging by KDIGO 2012, still used in studies
- Checked on
Summary of the published classification in our own words. Not a substitute for the original publication.
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