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vildagliptin

Galvus, Jalra, Xiliarx · ATC code A10BH02

Brand names: Galvus, Jalra, Xiliarx, Melkart, Saxotin, Vildabetes, Vildagliptin Al, Vildagliptin Amarox, Vildagliptin Axunio, Vildagliptin Denk, Vildagliptin Heumann, Vildagliptin Holsten, Vildagliptin Msn, Vildagliptin Olpha, Vildagliptin Stada …

Key facts
Active substance
vildagliptin
Drug class
Dipeptidyl peptidase-4 inhibitors
ATC code
A10BH02
Authorisation
centrally authorised across the EU (EMA)
Dosage forms
Galvus 50 mg tablets · Jalra 50 mg tablets · Xiliarx 50 mg tablets
Marketing authorisation holder
Novartis Europharm Limited
Information as of
2026-10-28

Key facts

Vildagliptin (Galvus, Jalra, Xiliarx) is an oral DPP-4 inhibitor used with diet and exercise to improve glycaemic control in adults with type 2 diabetes.

What it is used for

  • Monotherapy in adults with type 2 diabetes when metformin is inappropriate due to contraindications or intolerance.
  • In combination with other diabetes medicines, including insulin, when these do not provide adequate glycaemic control.

Dosing

  • Monotherapy and combinations with metformin, a thiazolidinedione, metformin plus a sulphonylurea, or insulin: 100 mg daily (50 mg in the morning and 50 mg in the evening).
  • Dual combination with a sulphonylurea: 50 mg once daily in the morning; a lower sulphonylurea dose may be considered to reduce hypoglycaemia.
  • Doses higher than 100 mg are not recommended.
  • Moderate or severe renal impairment or end-stage renal disease: 50 mg once daily; no adjustment with creatinine clearance ≥ 50 ml/min or in the elderly.
  • Do not use in hepatic impairment (including pre-treatment ALT/AST > 3x ULN); not recommended under 18 years.

Contraindications

  • Hypersensitivity to the active substance or any excipient.

Important warnings

  • Not a substitute for insulin; not for type 1 diabetes or diabetic ketoacidosis.
  • Rare hepatic dysfunction: check liver tests before starting, every three months in the first year and periodically thereafter; withdraw if AST/ALT ≥ 3x ULN persists.
  • Acute pancreatitis: discontinue if suspected and do not restart if confirmed.
  • Skin lesions including blistering and ulceration; not recommended in NYHA class IV.

Side effects

  • Mostly mild and transient.
  • Common include dizziness, headache, tremor, nausea, upper respiratory tract infection; hypoglycaemia mainly with sulphonylureas or insulin.
  • Not known: hepatitis, exfoliative and bullous skin lesions including bullous pemphigoid, cutaneous vasculitis.

Interactions

  • Low interaction potential; not a CYP450 substrate.
  • Possible increased risk of angioedema with ACE inhibitors.
  • The glucose-lowering effect may be reduced by certain active substances – see the full text.

Pregnancy and breastfeeding

  • Should not be used during pregnancy or breast-feeding.

Summary of the official product information, written with AI on 2026-10-29. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

Common questions – ask Medelix

For patients

Package leaflet, verbatim

This product has no separate US patient information.

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

EU – centrally authorised (all member states)

  • GalvusNovartis Europharm Limited · EMEA/H/C/000771
  • JalraNovartis Europharm Limited · EMEA/H/C/001048
  • XiliarxNovartis Europharm Limited · EMEA/H/C/001051

Source: European Medicines Agency (EMA), product information

Austria

  • MelkartG.L. Pharma Gmbh · 1 register entry
  • SaxotinSandoz Gmbh · 1 register entry
  • Vildagliptin1a Pharma Gmbh, Sandoz Gmbh, Teva B.V, Actavis Group Ptc Ehf., Accord Healthcare B.V., Hcs Bvba · 8 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29

Germany

  • VildabetesTad Pharma Gmbh · 1 register entry
  • Vildagliptin AlAliud Pharma Gmbh · 1 register entry
  • Vildagliptin AmaroxAmarox Pharma Gmbh · 1 register entry
  • Vildagliptin AxunioNio Health Gmbh · 1 register entry
  • Vildagliptin DenkDenk Pharma Gmbh & Co. Kg · 1 register entry
  • Vildagliptin HeumannHeumann Pharma Gmbh & Co. Generica Kg · 1 register entry
  • Vildagliptin HolstenHolsten Pharma Gmbh · 1 register entry
  • Vildagliptin MsnVivanta Generics S.R.O · 1 register entry
  • Vildagliptin OlphaOlpha As · 1 register entry
  • Vildagliptin StadaStadapharm Gmbh · 1 register entry
  • Vildagliptin VivantaVivanta Generics S.R.O · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29

Turkey

  • DiyatixSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • GalvusNOVARTİS SAĞLIK GIDA VE TARIM ÜRÜNLERİ SAN. VE TİC. A.Ş. · 2 register entries
  • GliptaABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • GlivantaVEM İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
  • GlividinRECORDATİ İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • OrvexiaWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • TaglinNOBEL İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • VefildaVEFA İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • VidaptinALİ RAİF İLAÇ SAN. A.Ş. · 1 register entry
  • ViglidaGENVEON İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • VilbiodaBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
  • VilcozaHELBA İLAÇ İÇ VE DIŞ SAN. TİC. A.Ş. · 3 register entries
Show all 16 brand names
  • VildabetİLKO İLAÇ SAN.VE TİC. A.Ş. · 2 register entries
  • VildalipNEUTEC İLAÇ SAN. TİC. A.Ş · 3 register entries
  • VildegaBİLİM İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • ViptinDR. SERTUS İLAÇ SAN. VE TİC. LTD. ŞTİ. · 2 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

Brand names in 27 more European countries
Belgium
Vildagliptin Krka
Bulgaria
Глипвило, Далмевин, Диптивил, Таглин
Croatia
Agnis, Dalmevin, Glypvilo, Saxotin, Vildagliptin Sandoz
Cyprus
Aglimon, Dalmevin, Diptivil, Videl, Vildagliptin Accord, Vildagliptin Vildagliptin Pharmathen
Czechia
Alikval, Anvildis, Dalmevin, Diptivil, Glypvilo, Melkart, Tutecvi, Viglita, Vildagliptin Accord, Vildagliptin Auxilto, Vildagliptin Auxpharma, Vildagliptin Olpha, Vildagliptin Sandoz, Vildagliptin Stada, Vildagliptin Zentiva
Denmark
Vildagliptin "a. E. Tiefenbacher", Vildagliptin "axunio", Vildagliptin "stada", Vildagliptin "tiefenbacher", Vildagliptin Aet, Vildagliptin Krka, Vildagliptin Stada, Vildagliptin Teva, Vildagliptin Vildaglipin "pharmathen"
Estonia
Dalmevin, Glypvilo, Saxotin, Vildagliptin Hexal, Vildagliptin Olpha
Finland
Vildagliptin Krka, Vildagliptin Ratiopharm, Vildagliptin Stada
France
Vildagliptine Accord, Vildagliptine Arrow, Vildagliptine Biogaran, Vildagliptine Eg, Vildagliptine Gnr Sandoz, Vildagliptine Intas, Vildagliptine Krka, Vildagliptine Olpha, Vildagliptine Sandoz, Vildagliptine Teva, Vildagliptine Tiefenbacher, Vildagliptine Viatris, Vildagliptine Zentiva, Vildagliptine Zydus
Greece
Dalmevin, Varbos, Vildaben, Vildafix, Vildagliptin Genepharm, Vildagliptin Iasis, Vildagliptin Nassington, Vildagliptin Pharmathen, Vildagliptin Stada, Vildagliptin Velka, Viltapin
Hungary
Agartha, Alikval, Anvildis, Diptivil, Glypvilo, Kwikaton, Melkart, Saxotin, Vildagliptin Hexal
Iceland
Galvus, Jalra, Vildagliptin Stada, Xiliarx
Ireland
Vildagliptin Krka
Italy
Vildagliptin Accord, Vildagliptin Aurobindo, Vildagliptin Doc, Vildagliptin Eg, Vildagliptin Krka, Vildagliptin Mylan, Vildagliptin Olpha, Vildagliptin Pensa, Vildagliptin Pharmacare, Vildagliptin Sandoz, Vildagliptin Teva
Latvia
Dalmevin, Glypvilo, Saxotin, Vildagliptin Hexal, Vildagliptin Olpha, Vildagliptin Unifarma
Liechtenstein
Galvus, Jalra, Xiliarx
Lithuania
Dalmevin, Glypvilo, Vildagliptin Olpha
Malta
Alikval, Dalmevin, Melkart, Vildaben, Vildabetes, Vildagliptin Adair, Vildagliptin Auxilto, Vildagliptin Denk, Vildagliptin Diagonalis, Vildagliptin Doc, Vildagliptin Galenicum, Vildagliptin Pharmacare, Vildagliptin Rafarm, Viltapin
Netherlands
Vilanov, Vildagliptine Accord, Vildagliptine Amarox, Vildagliptine Denk, Vildagliptine Intas, Vildagliptine Macleods
Norway
Galvus, Jalra, Vildagliptin Krka, Vildagliptin Mylan, Xiliarx
Poland
Anvildis, Diptivil, Gliptivil, Glypvilo, Kwikaton, Melkart, Viglita, Vildagliptin Olpha
Portugal
Tutecvi, Vezagla, Vildagliptin Ipca, Vildagliptina, Viltapin
Romania
Agartha, Dalmevin, Diptivil, Glypvilo, Melkart
Slovakia
Anvildis, Dalmevin, Diptivil, Glypvilo, Melkart, Vildagliptin Accord, Vildagliptin Olpha, Vildagliptin Stada
Slovenia
Glypvilo
Spain
Vildagliptina
Sweden
Dalmevin, Kwikaton, Vandetva, Vildagliptin Accord, Vildagliptin Krka, Vildagliptin Stada

EMA – Article 57 product data (EU/EEA), 2026-10-29

Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.

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Sources

  1. European Medicines Agency. Galvus – EPAR, Product Information. 2026-10-28. https://www.ema.europa.eu/en/documents/product-information/galvus-epar-product-information_en.pdf
  2. European Medicines Agency. Jalra – EPAR, Product Information. 2026-10-28. https://www.ema.europa.eu/en/documents/product-information/jalra-epar-product-information_en.pdf
  3. European Medicines Agency. Xiliarx – EPAR, Product Information. 2026-10-28. https://www.ema.europa.eu/en/documents/product-information/xiliarx-epar-product-information_en.pdf
  4. EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  5. EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  6. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
  7. Wikidata (CC0): ATC A10BH.

Editorial: Medelix editorial team · last updated 2026-10-28 · How these pages are made · Report an error

Source: European Medicines Agency (EMA), product information. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.