eGFR (CKD-EPI 2021)

Estimated glomerular filtration rate, race-free equation

eGFR (CKD-EPI 2021)

Estimated glomerular filtration rate, race-free equation

Sex
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Not valid in acute kidney injury, pregnancy, or at extremes of muscle mass. Drug dosing may still specify Cockcroft-Gault.

Source: Inker LA et al. New creatinine- and cystatin C-based equations without race. N Engl J Med 2021;385:1737-1749.Open

Interpretation

  • G5 — kidney failure — < 15 mL/min/1.73 m². Renal replacement therapy territory.
  • G4 — severely decreased — 15–29 mL/min/1.73 m².
  • G3b — moderately to severely decreased — 30–44 mL/min/1.73 m².
  • G3a — mildly to moderately decreased — 45–59 mL/min/1.73 m².
  • G2 — mildly decreased — 60–89 mL/min/1.73 m². CKD only with other evidence of kidney damage.
  • G1 — normal or high — ≥ 90 mL/min/1.73 m².

Not valid in acute kidney injury, pregnancy, or at extremes of muscle mass. Drug dosing may still specify Cockcroft-Gault.

Source: Inker LA et al. New creatinine- and cystatin C-based equations without race. N Engl J Med 2021;385:1737-1749.

These tools do not replace clinical judgement. Interpret the result in the context of the whole patient.