MedeliX
Start asking

Moxifloxacin

Avelox, Moxifloxacin · ATC code J01MA14

Also known as: Moksifloksasin, Moxifloxacin , 400 mg · Brand names: Avelox, Avalox, Vigamox, Atafloks, Demoxif, Emesmox, Kinomox, Mofelox, Moksefen, Moksilox, Moxacin, Moxai, Moxday, Moxhel, Moxicum …

Key facts
Active substance
Moxifloxacin
Drug class
Fluoroquinolone
ATC code
J01MA14
Authorisation
authorised nationally; no central EU authorisation
Information as of
2026-10-29

Boxed warning

  • Fluoroquinolones, including moxifloxacin hydrochloride, have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together [See warnings and Precautions (5.1)], including: Tendinitis and tendon rupture [See warnings and Precautions (5.2)] Peripheral Neuropathy [See warnings and Precautions (5.3) ] Central nervous system effects [See warnings and Precautions (5.4 )]

Discontinue moxifloxacin hydrochloride immediately and avoid the use of fluoroquinolones, including moxifloxacin hydrochloride, in patients who experience any of these serious adverse reactions [See warnings and Precautions (5.1)]

  • Fluoroquinolones, including moxifloxacin hydrochloride, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid moxifloxacin hydrochloride in patients with known history of myasthenia gravis [ See warnings and Precautions (5.5) ]
  • Because fluoroquinolones, including moxifloxacin hydrochloride, have been associated with serious adverse reactions [See warnings and Precautions (5.1 - 5.13 )], reserve moxifloxacin hydrochloride for use in patients who have no alternative treatment options for the following indications: Acute bacterial sinusitis [See Indications and Usage (1.6 )] Acute bacterial exacerbation of chronic bronchitis [See Indications and Usage (1.7)]

Key facts

Moxifloxacin is, per the US prescribing information, a fluoroquinolone antibiotic for bacterial infections in adults, including pneumonia, skin, intra-abdominal and respiratory infections, and plague.

What it is used for

  • Community acquired pneumonia, including multi-drug resistant Streptococcus pneumoniae.
  • Uncomplicated and complicated skin and skin structure infections; complicated intra-abdominal infections.
  • Plague (treatment and prophylaxis).
  • Acute bacterial sinusitis and acute bacterial exacerbation of chronic bronchitis only when there are no alternative treatment options.

Dosing

  • 400 mg once every 24 hours; duration depends on the infection: e.g. pneumonia 7 to 14 days, complicated skin infections 7 to 21 days, intra-abdominal infections 5 to 14 days, sinusitis 10 days, bronchitis exacerbation 5 days.
  • Take at least 4 hours before or 8 hours after products containing magnesium, aluminum, iron or zinc (e.g. antacids, sucralfate, multivitamins).
  • With or without food; drink fluids liberally.
  • No dose adjustment in renal impairment (including dialysis) or hepatic impairment; no adjustment when switching from intravenous to oral.

Contraindications

  • History of hypersensitivity to moxifloxacin or any other quinolone.

Important warnings

  • Boxed warning: disabling and potentially irreversible serious reactions such as tendinitis and tendon rupture, peripheral neuropathy and CNS effects – stop immediately; exacerbation of myasthenia gravis; for sinusitis and bronchitis exacerbation use only without alternatives.
  • Tendon risk is higher over 60 years of age, with corticosteroids and after kidney, heart or lung transplants.
  • QT prolongation: avoid with known QT prolongation, uncorrected hypokalemia or hypomagnesemia and Class IA or III antiarrhythmics.
  • Serious hypersensitivity reactions, Clostridium difficile-associated diarrhea, blood glucose disturbances and photosensitivity.

Side effects

  • Most common: nausea, diarrhea, headache and dizziness.
  • Postmarketing include ventricular tachyarrhythmias, hearing impairment, agranulocytosis, pancytopenia, and severe skin, liver and kidney reactions.

Interactions

  • Antacids, sucralfate, multivitamins and other multivalent cations substantially reduce absorption; separate the doses.
  • Warfarin: enhanced anticoagulant effect possible; monitor INR closely.
  • Antidiabetic agents: hypo- and hyperglycemia reported; monitor blood glucose.
  • Class IA (e.g. quinidine) and Class III (e.g. amiodarone, sotalol) antiarrhythmics: risk of QT prolongation.

Pregnancy and breastfeeding

  • No human data establish a drug-associated risk; based on animal studies, moxifloxacin may cause fetal harm.
  • It is not known whether moxifloxacin is present in human milk.

Summary of the official product information, written with AI on 2026-10-29. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

Common questions – ask Medelix

For patients

Patient information (US)

This product has no separate US patient information.

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

Austria

  • AveloxBayer Austria Gmbh · 2 register entries
  • Moxifloxacin1a Pharma Gmbh, Pharma Stulln Gmbh, Micro Labs Gmbh, Teva B.V, Noridem Enterprises Ltd, Sandoz Gmbh, Hikma Farmacêutica (Portugal), S.A., Stada Arzneimittel Gmbh, Fresenius Kabi Austria Gmbh, Krka, D.D., Novo Mesto · 12 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29

Germany

  • AvaloxBayer Vital Gmbh · 2 register entries
  • Moxifloxacin1 A Pharma Gmbh, Pharma Stulln Gmbh, Micro Labs Gmbh, Ratiopharm Gmbh, Puren Pharma Gmbh & Co. Kg, Hec Pharm Gmbh, Tillomed Pharma Gmbh, Holsten Pharma Gmbh, Noridem Enterprises Ltd, Dr. Friedrich Eberth Arzneimittel Gmbh, Stadapharm Gmbh, Novartis Pharma Gmbh, Fresenius Kabi Deutschland Gmbh, Abz-Pharma Gmbh, Tad Pharma Gmbh, Aliud Pharma Gmbh · 21 register entries
  • VigamoxNovartis Pharma Gmbh · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29

Turkey

  • AtafloksATABAY KİMYA SAN. VE TİC. A.Ş. · 1 register entry
  • AveloxBAYER TÜRK KİMYA SAN. LTD. ŞTİ. · 3 register entries
  • DemoxifDEVA HOLDİNG A.Ş. · 3 register entries
  • EmesmoxSM PHARMA İLAÇ SAN. LTD. ŞTİ. · 1 register entry
  • KinomoxPHARMATRUE SAĞLIK MALZEMELERİ A.Ş. · 1 register entry
  • MofeloxKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 2 register entries
  • MoksefenİLKO İLAÇ SAN.VE TİC. A.Ş. · 2 register entries
  • MoksiloxPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
  • MoxacinVEM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • MoxaiABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • MoxdayNEUTEC İLAÇ SAN. TİC. A.Ş · 2 register entries
  • MoxhelHELBA İLAÇ İÇ VE DIŞ SAN. TİC. A.Ş. · 1 register entry
Show all 23 brand names
  • MoxicumWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • MoxifixAY PHARMACY İLAÇ TİC. A.Ş. · 1 register entry
  • MoxiforBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • MoxiitecBASEL KİMYEVİ MAD. VE İLAÇ SAN. TİC. A.Ş. · 1 register entry
  • MoxiprecNOBEL İLAÇ PAZARLAMA VE SAN. LTD. ŞTİ. · 1 register entry
  • MoxitabLİLYUM İLAÇ VE KİMYA SAN. TİC. A.Ş. · 3 register entries
  • MoxitecBASEL KİMYEVİ MAD. VE İLAÇ SAN. TİC. A.Ş. · 1 register entry
  • Multiflex MoxiflexHAVER FARMA İLAÇ A.Ş. · 1 register entry
  • PitoxilSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
  • PnemoxTÜM-EKİP İLAÇ A.Ş. · 1 register entry
  • Turktipsan MoksifloksasinTURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş. · 2 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

USA

  • VigamoxHarrow Eye, LLC · 1 register entry

Source: U.S. FDA – Drug labels (openFDA/DailyMed), as of 2026-10-29

Brand names in 27 more European countries
Belgium
Avelox, Kanavig, Moxifloxacin Ab, Moxifloxacin Sandoz, Moxifloxacine Eg, Moxifloxacine Fresenius Kabi, Moxifloxacine Sandoz, Moxifloxacine Teva
Bulgaria
Cimocinox, Moxifloxacin Kabi, Авелокс, Айсокс, Бивокса, Вигамокс, Ерелан, Кимокс, Ксифлодроп, Мокси, Моксиквин, Моксистад, Моксифлоксан, Молоксин
Croatia
Melvedok, Moksacin, Moksifloksacin Pharmas, Moloxin, Moxifloxacin Kabi
Cyprus
Avelox, Erelan, Moxifalon T, Moxifloxacin Noridem, Vigamox
Czechia
Avelox, Moxifloxacin Brown & Burk, Moxifloxacin Kabi, Moxifloxacin Olikla, Vigamox
Denmark
Moxifloxacin Accord, Moxifloxacin Fresenius Kabi, Moxifloxacin Krka, Moxifloxacin Orion, Moxifloxacin Pharmathen, Moxiva, Rivomoxi, Vamocin, Vigamox, Xiflodrop
Estonia
Avelox, Floxelan, Lifodrox, Moflaxa, Vigamox
Finland
Moxifloxacin Fresenius Kabi, Moxifloxacin Krka, Moxifloxacin Orion, Moxifloxacin Sanoswiss, Moxifloxacin Stada, Vigamox
France
Izilox, Moxifloxacine Arrow, Moxifloxacine Biogaran, Moxifloxacine Eg, Moxifloxacine Krka, Moxifloxacine La Colina, Moxifloxacine Sandoz, Moxifloxacine Viatris
Greece
Avelox, Mikrobiel, Moflotrex Pf, Moflotrex Ud, Moxifalon, Moxifloxacin Sandoz, Moxifloxacin Vioser, Oflokasin, Rucela, Tamvelier, Vigamox
Hungary
Moxibiot, Moxifloxacin Anfarm, Moxifloxacin Kabi, Moxifloxacin Ratiopharm, Moxifloxacin Reiwa Healthcare, Moxifloxacin Teva, Vigamox
Iceland
Vigamox
Ireland
Moxifloxacin
Italy
Avalox, Moxidrop, Moxifloxacina Aurobindo, Moxifloxacina Krka, Moxifloxacina Pensa, Moxifloxacina Teva, Omnimoxa, Oxa, Quimox, Vigamox
Latvia
Avelox, Ekara, Lifodrox, Moxifloxacin Sandoz, Vigamox
Lithuania
Avelox, Ekara, Floxelan, Lifodrox, Moflaxa, Moxifloxacin Sandoz, Vigamox
Luxembourg
Avelox, Kanavig, Moxifloxacin Micro Labs, Moxifloxacin Ratiopharm, Moxifloxacin Sanovel, Moxifloxacine Eg, Moxifloxacine Fresenius Kabi
Malta
Erelan, Moxifloxacin Anfarm, Vigamox
Netherlands
Erelan, Moxifloxacin Hydrochloride Aurobindo, Moxifloxacine Fresenius Kabi, Moxifloxacine Msn, Moxifloxacine Sandoz, Moxifloxacine Stulln, Moxifloxacine Teva, Moxifloxacine Vioser, Vigamox
Norway
Xinaflox
Poland
Flomixa, Kimoks, Moloxin, Monafox, Moxifloxacin Aurovitas, Moxifloxacinum Brown & Burk, Moxifloxacinum Stulln, Vigamox, Xiflodrop
Portugal
Avelox, Bluesar, Moflok, Moxifloxacina Anfarm, Moxifloxacina Aurobindo, Moxifloxacina Aurovitas, Moxifloxacina Bluepharma, Moxifloxacina Ciclum, Moxifloxacina Demo, Moxifloxacina Hikma, Moxifloxacina Krka, Moxifloxacina Meren, Moxifloxacina Mylan, Moxifloxacina Oara, Moxifloxacina Rompharm, Vigamox
Romania
Avelox, Kimoks, Moflaxa, Moxifloxacina Kabi, Moxifloxacină Brown & Burk, Moxifloxacină Rompharm, Vigamox
Slovakia
Avelox, Moloxin, Moxifloxacin Kabi, Moxifloxacin Olikla, Vigamox
Slovenia
Kimoks, Moksifloksacin Kabi, Moksifloksacin Stada, Moloxin, Vigamox
Spain
Abimox, Actira, Erelan, Moxifloxacino Aurovitas, Moxifloxacino Cinfa, Moxifloxacino Kabi, Moxifloxacino Kern Pharma, Moxifloxacino Krka, Moxifloxacino Normon, Moxifloxacino Pensa, Moxifloxacino Qualigen, Moxifloxacino Reiwa Healthcare, Moxifloxacino Sandoz, Moxifloxacino Stada, Moxifloxacino Tevagen, Moxifloxacino Viatris, Omnimoxa, Vigamox
Sweden
Moxifloxacin Fresenius Kabi, Moxifloxacin Krka, Moxifloxacin Orion, Rivomoxi, Vigamox

EMA – Article 57 product data (EU/EEA), 2026-10-29

Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.

Other substances in the same group

Related calculators

Another question about this substance?

Medelix answers clinical questions from guidelines, studies and product information – every claim with its source.

Sources

  1. U.S. Food and Drug Administration. Moxifloxacin Hydrochloride Tablets, 400 mg (Novadoz Pharmaceuticals LLC) – Prescribing Information, 2019-04-20. DailyMed (NLM), 2026-10-29. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=04e0936f-2248-48e4-8031-ac6ccc2df294
  2. EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  3. EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
  5. U.S. FDA – Drug labels (openFDA/DailyMed), 2026-10-29. https://dailymed.nlm.nih.gov/dailymed/
  6. Wikidata (CC0): ATC J01MA.

Editorial: Medelix editorial team · last updated 2026-10-29 · How these pages are made · Report an error

Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.