Ciprofloxacin
Ciflox, Ciloxan, Ciprofloxacin, Cipromed · ATC code J01MA02
Also known as: siprofloksasin · Brand names: Ciflox, Ciloxan, Cipromed, Ciprostad, Ciproxin, Otanol, Cipro, Ciprobay, Ciprobay®, Ciprofloxacin Abz, Ciprofloxacin Al, Ciprofloxacin Aristo, Ciprofloxacin Hameln, Ciprofloxacin Hec Pharm, Ciprofloxacin Hikma …
- Key facts
- Active substance
- Ciprofloxacin
- Drug class
- Fluoroquinolone
- ATC code
- J01MA02
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-27
Boxed warning
• Fluoroquinolones, including ciprofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together [see Warnings and Precautions ( 5.1)], including:
• Tendinitis and tendon rupture [see Warnings and Precautions ( 5.2)].
• Peripheral neuropathy [see Warnings and Precautions ( 5.3)].
• Central nervous system effects [see Warnings and Precautions ( 5.4)].
• Discontinue ciprofloxacin immediately and avoid the use of fluoroquinolones, including ciprofloxacin, in patients who experience any of these serious adverse reactions [see Warnings and Precautions ( 5.1)] . Fluoroquinolones, including ciprofloxacin, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid ciprofloxacin in patients with known history of myasthenia gravis [see Warnings and Precautions ( 5.5)].
• Because fluoroquinolones, including ciprofloxacin, have been associated with serious adverse reactions [see Warnings and Precautions ( 5.1-5.16 )], reserve ciprofloxacin for use in patients who have no alternative treatment options for the following indications:
• Acute exacerbation of chronic bronchitis [see Indications and Usage ( 1.10)].
• Acute uncomplicated cystitis [see Indications and Usage ( 1.11)].
• Acute sinusitis [see Indications and Usage ( 1.12)].
Key facts
Ciprofloxacin is a fluoroquinolone antibacterial. It is used for various bacterial infections, including skin, bone and joint, urinary tract, respiratory and intra-abdominal infections.
What it is used for
- Adults: skin and skin structure, bone and joint, and complicated intra-abdominal infections (with metronidazole)
- Adults: infectious diarrhea, typhoid fever, gonococcal infections, chronic bacterial prostatitis, lower respiratory and urinary tract infections
- Inhalational anthrax (post-exposure, also in children) and plague
- Children 1 to 17 years: complicated urinary tract infection or pyelonephritis
- Acute exacerbation of chronic bronchitis, acute uncomplicated cystitis and acute sinusitis only when no alternatives exist
Dosing
- Adults, by infection: 250 mg to 750 mg every 12 hours; e.g. 7 to 14 days for skin and urinary tract infections, 4 to 8 weeks for bone and joint infections
- Acute uncomplicated cystitis: 250 mg every 12 hours for 3 days
- Inhalational anthrax (post-exposure): 500 mg every 12 hours for 60 days
- Children with complicated UTI: 10 mg/kg to 20 mg/kg every 12 hours, maximum 750 mg per dose
- Dose and duration depend on infection severity, organism, and renal and hepatic function; further regimens in the full prescribing information
Contraindications
- Hypersensitivity to ciprofloxacin, any quinolone or product components
- Concomitant tizanidine
Important warnings
- Boxed warning: disabling, potentially irreversible serious reactions – tendinitis and tendon rupture, peripheral neuropathy, CNS effects; discontinue immediately if they occur
- May exacerbate muscle weakness in myasthenia gravis; avoid with a history of myasthenia gravis
- Hypersensitivity reactions, hepatotoxicity, risk of aortic aneurysm and dissection
- QT prolongation, Clostridium difficile-associated diarrhea, photosensitivity
- Musculoskeletal disorders in pediatric patients
Side effects
- Tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy
- CNS effects: hallucinations, anxiety, depression, insomnia, severe headaches, confusion
- Serious: hepatotoxicity, hypersensitivity reactions, serious reactions with concomitant theophylline
Interactions
- Tizanidine: contraindicated (potentiated hypotensive and sedative effects)
- Ciprofloxacin inhibits CYP1A2: raised levels of drugs metabolized by CYP1A2, such as theophylline
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
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Patient information (US)
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- CifloxG.L. Pharma Gmbh · 1 register entry
- CiloxanNovartis Pharma Gmbh · 1 register entry
- Ciprofloxacin1a Pharma Gmbh, Teva B.V, +pharma Arzneimittel Gmbh, Noridem Enterprises Ltd, Sandoz Gmbh, Hikma Farmacêutica (Portugal), S.A., Fresenius Kabi Austria Gmbh, Krka, D.D., Novo Mesto · 8 register entries
- CipromedS.Med Handelsgmbh · 1 register entry
- CiprostadStada Arzneimittel Gmbh · 1 register entry
- CiproxinBayer Austria Gmbh · 1 register entry
- OtanolGebro Pharma Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- CiloxanNovartis Pharma Gmbh · 2 register entries
- Cipro1 A Pharma Gmbh, Basics Gmbh, Denk Pharma Gmbh & Co. Kg, Tad Pharma Gmbh · 4 register entries
- CiprobayBayer Vital Gmbh · 1 register entry
- Ciprobay®Bayer Vital Gmbh · 1 register entry
- Ciprofloxacin AbzAbz-Pharma Gmbh · 1 register entry
- Ciprofloxacin AlAliud Pharma Gmbh · 1 register entry
- Ciprofloxacin AristoAristo Pharma Gmbh (Art 57) · 1 register entry
- Ciprofloxacin HamelnHameln Pharma Gmbh · 1 register entry
- Ciprofloxacin Hec PharmHec Pharm Gmbh · 1 register entry
- Ciprofloxacin HikmaHikma Farmacêutica (Portugal), S.A. · 1 register entry
- Ciprofloxacin KabiFresenius Kabi Deutschland Gmbh · 1 register entry
- Ciprofloxacin Noridem EnterprisesNoridem Enterprises Ltd · 1 register entry
Show all 17 brand names
- Ciprofloxacin RatiopharmRatiopharm Gmbh · 2 register entries
- Ciprofloxacin StadaStadapharm Gmbh · 1 register entry
- CiprohexalHexal Ag · 2 register entries
- Infectocipro®Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim · 1 register entry
- Panotile CiproPierre Fabre Pharma Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- BaysipİSTANBUL İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- CarploxanCAROLINA PHARMA İLAÇ VE KİMYEVİ MADDELER SAN. VE TİC. LTD. ŞTİ. · 2 register entries
- CiflosinDEVA HOLDİNG A.Ş. · 5 register entries
- CipocinALİ RAİF İLAÇ SAN. A.Ş. · 3 register entries
- CiprasidRECORDATİ İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- CiproBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 6 register entries
- CiprocamHELBA İLAÇ İÇ VE DIŞ SAN. TİC. A.Ş. · 2 register entries
- CiprodeksPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- CiproktanKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 5 register entries
- CiprolonOSEL İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- CipronatinATABAY KİMYA SAN. VE TİC. A.Ş. · 5 register entries
- CipropolPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
Show all 33 brand names
- EradiksASET İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- FloticVEM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- KinosinBİLİM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- LoxasidTOPRAK İLAÇ VE KİMYEVİ MADDELER SAN.VE TİC. A.Ş. · 2 register entries
- NovarexHTA İLAÇ ARAŞTIRMA GELİŞTİRME SAN.VE TİC. LTD. ŞTİ. · 2 register entries
- ProxacinYAVUZ İLAÇ ECZA DEPOSU MEDİKAL ÜRÜNLER SAN.VE TİC. A.Ş. · 2 register entries
- QuinoxSANTASYA İLAÇ KOZMETİK MEDİKAL İTRİYAT PAZARLAMA SAĞLIK HİZMETLERİ VE İNŞAAT SAN. TİC. LTD. ŞTİ. · 2 register entries
- RofacidMENTA PHARMA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- RoflazinUMUT İLAÇ TİC. VE SAN. LTD. ŞTİ., MÜNİR ŞAHİN İLAÇ SAN. VE TİC A.Ş. · 3 register entries
- RoxinMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 2 register entries
- SanfloksSANDOZ İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- SansetSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- Selfleks CipraselHAVER FARMA İLAÇ A.Ş. · 2 register entries
- SifloksAVİXA İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
- SiploneWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- SiprobelNOBEL İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- SiprojectTÜM-EKİP İLAÇ A.Ş. · 2 register entries
- SiprosanDROGSAN İLAÇLARI SAN. VE TİC. A.Ş. · 3 register entries
- SispresULKAR KİMYA SAN. VE TİC. A.Ş. · 2 register entries
- SloxacinHAVER TRAKYA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- VonecipPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
USA
- CiloxanSandoz Inc · 1 register entry
- CiproBayer HealthCare Pharmaceuticals Inc. · 1 register entry
Source: U.S. FDA – Drug labels (openFDA/DailyMed), as of 2026-10-28
Brand names in 27 more European countries
- Belgium
- Ciloxan, Ciprofloxacine Ab, Ciprofloxacine Eg, Ciprofloxacine Fresenius Kabi, Ciprofloxacine Sandoz, Ciprofloxacine Teva, Ciprofloxacine Viatris, Ciproxine
- Bulgaria
- Ciprofloxacin World Medicine Europe Eood, Орпикс, Цилоксан, Ципринол, Ципробай, Ципрофлав, Ципрофлоксан, Ципрофлоксацин Актавис, Ципрофлоксацин Алкалоид, Ципрофлоксацин Екофарм, Ципрофлоксацин Софарма
- Croatia
- Ciflox, Ciloxan, Ciprinol, Ciprofloksacin Jgl, Ciprofloksacin Sandoz, Ciprofloxacin Kabi, Cipromed, Citeral
- Cyprus
- Cifloxacin, Ciloxan, Ciproflox, Ciprofloxacin Remedica, Ciprofloxacin Vioser, Ciproxin, Droll, Medociprin, Nafloxin, Syntoflox, Topistin, Ufexil, Viprolox, Zindolin
- Czechia
- Cifloxinal, Ciloxan, Ciprinol, Ciprofloxacin Kabi
- Denmark
- Cetraxal, Cifin, Ciloxan, Ciprofloxacin "hexal", Ciprofloxacin Actavis, Ciprofloxacin Fresenius Kabi, Ciprofloxacin Hexal, Ciprofloxacin Krka, Ciprofloxacin Navamedic, Ciprofloxacin Orion, Ciprofloxacin Pharmathen, Ciprofloxacin Teva
- Estonia
- Ciloxan, Ciprinol, Ciprofloxacin Basi, Ciprofloxacin Norameda, Ciprofloxacin Olpha, Ciprofloxacin Sandoz
- Finland
- Cetraxal, Ciprofloxacin Fresenius Kab, Ciprofloxacin Fresenius Kabi, Ciprofloxacin Krka, Ciprofloxacin Navamedic, Ciprofloxacin Orion, Ciprofloxacin Ratiopharm, Ciproxin
- France
- Ciflox, Ciloxan, Ciprofloxacine Accord, Ciprofloxacine Aguettant, Ciprofloxacine Arrow, Ciprofloxacine Benta, Ciprofloxacine Biogaran, Ciprofloxacine Cristers Pharma, Ciprofloxacine Eg, Ciprofloxacine Evolugen, Ciprofloxacine Kabi, Ciprofloxacine Panpharma, Ciprofloxacine Sandoz, Ciprofloxacine Teva, Ciprofloxacine Viatris, Ciprofloxacine Zentiva, Ciprofloxacine Zydus, Uniflox
- Greece
- Aristin-C, Bivorilan, Cetraxal, Cifloxacin, Cipratic, Ciprocton®, Ciprofal, Ciprofloxacin, Cipromycin/Medichrom, Ciprovian®, Ciproxin, Citrovenot, Droll, Flociprin, Forterra, Ginorectol, Grenis-Cipro, Labentrol, Ladinin, Limox, Nafloxin, Ravalton, Revionorm, Topistin, Ufexil, Unifloxin, Urodixin, Αristin – C
- Hungary
- Cifloxin, Cifran, Ciloxan, Ciprinol, Ciprobay, Ciprofloxacin-Human Teva, Ciprofloxacin Kabi, Grenis-Cipro
- Iceland
- Cetraxal, Ciprofloxacin Alvogen, Ciprofloxacin Fresenius Kabi, Ciprofloxacin Navamedic, Síprox
- Ireland
- Cifloxager, Cifox, Ciloxan, Ciprofloxacin Krka, Ciprofloxacin Noridem Enterprises, Ciprofloxacin Teva, Profloxin, Truoxin Iv
- Italy
- Basemar, Battizer, Bosix, Cetraflux, Chinocid, Ciperus, Ciprofloxacin Ratiopharm, Ciprofloxacina Abc, Ciprofloxacina Accord, Ciprofloxacina Almus, Ciprofloxacina Alter, Ciprofloxacina Aurobindo, Ciprofloxacina Bioindustria L.I.M., Ciprofloxacina Doc Generici, Ciprofloxacina Eg, Ciprofloxacina Galenica Senese, Ciprofloxacina Hikma, Ciprofloxacina Kabi, Ciprofloxacina Krka, Ciprofloxacina Mylan Generics, Ciprofloxacina Pensa, Ciprofloxacina Pharmacare, Ciprofloxacina Ratiopharm, Ciprofloxacina Sandoz, Ciprofloxacina Tecnigen, Ciprofloxacina Zentiva, Ciproxin, Cuspis, Eoxin, Flontalexin, Generflon, Ibixacin, Kinox, Macar, Oftacilox, Prociflor, Samper, Ullax, Unicexal
- Latvia
- Cifran, Ciloxan, Ciprinol, Ciprofloxacin Aurobindo, Ciprofloxacin Basi, Ciprofloxacin Norameda, Ciprofloxacin Olpha, Ciprofloxacin Sandoz, Ciprofloxacin Unifarma, Cipronex
- Lithuania
- Cifran, Ciloxan, Ciprinol, Ciprofloxacin Actavis, Ciprofloxacin Basi, Ciprofloxacin Norameda, Ciprofloxacin Sandoz, Quintor
- Luxembourg
- Ciloxan, Ciprofloxacin Kabi, Ciprofloxacin Ratiopharm, Ciprofloxacine Ab, Ciprofloxacine Eg, Ciprofloxacine Viatris, Ciproxine
- Malta
- Aristin-C, Cifox, Ciloxan, Ciprinol, Ciprofloxacin Accord Healthcare, Ciprofloxacin Kabi, Ciprofloxacin Noridem Enterprises, Medociprin, Nafloxin, Profloxin, Viprolox, Zindolin
- Netherlands
- Cetraxal, Ciprinol, Ciprofloxacin Aurobindo, Ciprofloxacin Hameln, Ciprofloxacine
- Norway
- Cetraxal, Cilox, Ciprofloxacin Actavis, Ciprofloxacin Navamedic
- Poland
- Cetraxal, Ciloxan, Ciphin, Ciprinol, Ciprofloxacin Kabi, Cipronex, Cipropol, Proxacin
- Portugal
- Cetraflux, Ciplox, Ciprofloxacin Ratiopharm, Ciprofloxacina Alter, Ciprofloxacina Aurovitas, Ciprofloxacina Azevedos, Ciprofloxacina Basi, Ciprofloxacina Bluepharma, Ciprofloxacina Ciclum, Ciprofloxacina Farmoz, Ciprofloxacina Generis, Ciprofloxacina Gp, Ciprofloxacina Hikma, Ciprofloxacina Kabi, Ciprofloxacina Krka, Ciprofloxacina Megaflox, Ciprofloxacina Normon, Ciprofloxacina Omnicals, Ciprofloxacina Pentafarma, Ciprofloxacina Pharmakern, Ciprofloxacina Ratiopharm, Ciprofloxacina Sandoz, Ciprofloxacina Tetrafarma, Ciprofloxacina Tolife, Ciprofloxacina Viatris, Ciprofloxacina Vitória, Ciprofloxacina Wynn, Ciproxina, Giroflox, Nivoflox, Oftacilox, Quinox
- Romania
- Cifran, Ciprinol, Cipro Inf, Cipro Quin, Ciprocin, Ciprofloxacin Rompharm, Ciprofloxacina Vioser, Ciprolen, Cuminol
- Slovakia
- Ciphin, Ciprinol, Ciprofloxacin Kabi, Ciprofloxacin Teva, Ciprofloxacín Sandoz, Ciprolon, Medociprin
- Slovenia
- Ciloxan, Ciprinol, Ciprofloksacin Lek
- Spain
- Aceoto, Cetraflux, Cetraxal, Ciflot, Ciprofloxacino Altan, Ciprofloxacino Alter, Ciprofloxacino Aurovitas, Ciprofloxacino Basi, Ciprofloxacino Cinfa, Ciprofloxacino Combix, Ciprofloxacino Dermogen, Ciprofloxacino Fresenius Kabi, Ciprofloxacino Kabi, Ciprofloxacino Kern Pharma, Ciprofloxacino Normon, Ciprofloxacino Pensa, Ciprofloxacino Qualigen, Ciprofloxacino Stada, Ciprofloxacino Sun, Ciprofloxacino Tarbis, Ciprofloxacino Vir, Doriman, Oftacilox, Otociprin Ótico, Septocipro Ótico
- Sweden
- Cetraxal, Ciloxan, Ciprofloxacin Accord, Ciprofloxacin Bluefish, Ciprofloxacin Fresenius Kabi, Ciprofloxacin Hexal, Ciprofloxacin Krka, Ciprofloxacin Navamedic, Ciprofloxacin Orion, Ciprofloxacin Sun, Ciprofloxacin Viatris
EMA – Article 57 product data (EU/EEA), 2026-10-28
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Sources
- U.S. Food and Drug Administration. Ciprofloxacin (Yiling Pharmaceutical, Inc.) – Prescribing Information, 2025-12-29. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=6fd3da0b-7428-ac8f-e053-2a91aa0aed9f
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
- U.S. FDA – Drug labels (openFDA/DailyMed), 2026-10-28. https://dailymed.nlm.nih.gov/dailymed/
- Wikidata (CC0): ATC J01MA.
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.