Sertraline
Adjuvin, Sertralin, Tresleen · ATC code N06AB06
Also known as: Sertralin · Brand names: Adjuvin, Tresleen, Sertralon, Zoloft, As-Sertral, Lustec, Lustral, Misol, Olinar, Selectra, Serotop
- Key facts
- Active substance
- Sertraline
- Drug class
- Selective serotonin reuptake inhibitor
- ATC code
- N06AB06
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-27
Boxed warning
Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies. Closely monitor all antidepressant-treated patients for clinical worsening, and for emergence of suicidal thoughts and behaviors [See Warnings and Precautions (5.1)].
Key facts
Sertraline is a selective serotonin reuptake inhibitor (SSRI). Per the US label it is used for major depressive disorder, OCD, panic disorder, PTSD, social anxiety disorder and premenstrual dysphoric disorder.
What it is used for
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD), including pediatric patients aged 6 and older
- Panic disorder, posttraumatic stress disorder (PTSD), social anxiety disorder
- Premenstrual dysphoric disorder (PMDD)
Dosing
- Adults: starting dose 50 mg/day for MDD and OCD, 25 mg/day for panic disorder, PTSD and social anxiety disorder
- May be increased by 25 to 50 mg per day once a week up to a maximum of 200 mg per day
- Pediatric OCD: ages 6 to 12 start 25 mg, ages 13 to 17 start 50 mg
- PMDD: 50 mg/day, continuously (up to 150 mg) or in the luteal phase only (up to 100 mg)
- Mild hepatic impairment: half the dosage; moderate or severe hepatic impairment: not recommended
- Screen for bipolar disorder before starting
Contraindications
- Taking MAOIs (including linezolid and IV methylene blue) or within 14 days of stopping them
- Taking pimozide
- Known hypersensitivity to sertraline
Important warnings
- Boxed warning: increased risk of suicidal thoughts and behaviors in pediatric and young adult patients; monitor closely
- Serotonin syndrome, especially with other serotonergic drugs
- Increased risk of bleeding; activation of mania/hypomania
- Discontinuation syndrome, seizures, angle-closure glaucoma, hyponatremia, sexual dysfunction
Side effects
- Most common: nausea, diarrhea, tremor, dyspepsia, decreased appetite, hyperhidrosis, ejaculation failure, decreased libido
- By indication also somnolence, insomnia, agitation, constipation, fatigue
Interactions
- MAOIs: risk of serotonin syndrome, contraindicated
- Pimozide: increased levels with risk of QTc prolongation and arrhythmias, contraindicated
- Other serotonergic drugs and drugs affecting hemostasis: caution (details in the full text)
Pregnancy and breastfeeding
- SSRI exposure in the month before delivery has been associated with an increased risk of postpartum hemorrhage; neonatal complications possible after third-trimester exposure
- Low levels are present in human milk
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
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For patients
Patient information (US)
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- AdjuvinG.L. Pharma Gmbh · 1 register entry
- Sertralin1a Pharma Gmbh, Teva B.V, Bluefish Pharmaceuticals Ab, +pharma Arzneimittel Gmbh, Actavis Group Ptc Ehf., Viatris Healthcare Limited, Zentiva, K.S., Accord Healthcare B.V., Sandoz Gmbh, Hexal Pharma Gmbh, Stada Arzneimittel Gmbh, G.L. Pharma Gmbh, Krka, D.D., Novo Mesto · 13 register entries
- TresleenViatris Healthcare Limited · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- SertralinPuren Pharma Gmbh & Co. Kg, 1 A Pharma Gmbh, Neuraxpharm Arzneimittel Gmbh, Aaa-Pharma Gmbh, Ratiopharm Gmbh, Medical Valley Invest Ab, Bluefish Pharmaceuticals Ab, Winthrop Arzneimittel Gmbh, Heumann Pharma Gmbh & Co. Generica Kg, Zentiva Pharma Gmbh, Accord Healthcare B.V., Amarox Pharma Gmbh, Basics Gmbh, Hexal Ag, Stadapharm Gmbh, Betapharm Arzneimittel Gmbh, Viatris Germany Gmbh, Abz-Pharma Gmbh, Tad Pharma Gmbh, Aliud Pharma Gmbh · 22 register entries
- SertralonHolsten Pharma Gmbh · 1 register entry
- ZoloftViatris Pharma Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- As-SertralAPOTEX İLAÇ SAN VE TİC. LTD. ŞTİ. · 3 register entries
- LustecBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- LustralVİATRİS İLAÇLARI LİMİTED ŞİRKETİ · 7 register entries
- MisolNOBEL İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- OlinarALİ RAİF İLAÇ SAN. A.Ş. · 4 register entries
- SelectraSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- SerotopSANDOZ İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
Brand names in 27 more European countries
- Belgium
- Serlain, Sertraline Ab, Sertraline Eg, Sertraline Sandoz, Sertraline Teva, Sertraline Viatris
- Bulgaria
- Асентра, Золофт, Мисол, Сеталофт, Стимулотон
- Croatia
- Asentra, Luxeta, Sonalia, Zoloft
- Cyprus
- Enidap, Sertraline Accord, Trenel, Zoloft
- Czechia
- Adjuvin, Aflizan, Asentra, Sertivan, Sertralin Actavis, Sertralin Krka, Sertralin Viatris, Sertralin Vipharm, Sertraline Accord, Sertraline Farmax, Sertraline Medreg, Setaloft, Stimuloton, Zoloft
- Denmark
- Sertralin "hexal", Sertralin Accord, Sertralin Krka, Sertralin Orion, Sertralin Teva, Sertralin Zentiva, Sertraline Medical Valley, Sertraline Orifarm, Sertramyl, Sertrone, Zoloft
- Estonia
- Asentra, Sertraline Accord, Sertraline Teva, Zoloft
- Finland
- Sertralin Hexal, Sertralin Krka, Sertralin Orion, Sertralin Ratiopharm, Sertraline Accord, Zoloft
- France
- Sertraline Almus, Sertraline Arrow Lab, Sertraline Biogaran, Sertraline Cristers, Sertraline Eg, Sertraline Evolugen, Sertraline Sandoz, Sertraline Teva, Sertraline Viatris, Sertraline Zentiva, Sertraline Zydus France, Zoloft
- Greece
- Certorun, Enidap, Epilyd, Neurosedine, Serolux, Serotyp, Sertral, Zoloft, Zolotrin, Zortal
- Hungary
- Asentra, Sertadepi, Sertagen, Sertralin Sandoz, Sertralin Zentiva, Sertraline Svus, Sertraline Teva, Stimuloton, Zoloft
- Iceland
- Sertral, Sertralin Bluefish, Sertralin Krka, Sertralin Wh, Sertraline Medical Valley, Zoloft
- Ireland
- Depreger, Lustral, Seretral, Serimel, Serlan, Sertraline Accord Healthcare Ireland, Sertraline Bluefish, Sertraline Krka
- Italy
- Sertralina Accord, Sertralina Almus, Sertralina Alter, Sertralina Aurobindo, Sertralina Doc Generici, Sertralina Eg Stada, Sertralina Hexal, Sertralina Krka, Sertralina Medreg, Sertralina Mylan Generics, Sertralina Pensa, Sertralina Ranbaxy, Sertralina Sandoz, Sertralina Sun Pharma Italia Srl, Sertralina Tecnigen, Sertralina Teva Pharma, Sertralina Zentiva, Sertraline Teva Pharma B.V., Tatig, Zoloft
- Latvia
- Asentra, Sertralin Actavis, Sertraline Accord, Sertraline Lannacher, Zoloft
- Lithuania
- Asentra, Sertralin Actavis, Sertralin Orion, Zoloft
- Luxembourg
- Serlain, Sertralin Ratiopharm, Sertraline Eg, Sertraline Viatris
- Malta
- Serimel, Serlan, Sertraline Aurobindo, Sertraline Normon
- Netherlands
- Asentra, Sertraline, Zoloft
- Norway
- Sertralin Bluefish, Sertralin Hexal, Sertralin Zentiva, Sertraline Accord, Sertraline Medical Valley, Sertraline Orifarm, Zoloft
- Poland
- Apiolin, Aposerta, Asentra, Asertin, Miravil, Sastium, Sertagen, Sertralina Krka, Sertraline Farmax, Sertraline Medical Valley, Sertraline Medreg, Sertranorm, Setaloft, Stimuloton, Zoloft, Zotral
- Portugal
- Ainim, Semonic, Sertralina Alter, Sertralina Aserta, Sertralina Aurobindo, Sertralina Aurovitas, Sertralina Azevedos, Sertralina Basi, Sertralina Bluefish, Sertralina Bluepharma, Sertralina Ciclum, Sertralina Farmoz, Sertralina Genedec, Sertralina Generis, Sertralina Gerlina Bluemed Unipessoal, Sertralina J. Neves, Sertralina Krka, Sertralina Mylan, Sertralina Neuraxpharm, Sertralina Pensa, Sertralina Pharmakern, Sertralina Ratiopharm, Sertralina Sandoz, Sertralina Stada, Sertralina Svus, Sertralina Tetrafarma, Sertralina Teva, Sertralina Tolife, Sertralina Wynn, Sertralina Zentiva, Zoloft
- Romania
- Asentra, Serlift, Sertralină Arena, Sertralină Gemax Pharma, Stimuloton, Zoloft
- Slovakia
- Asentra, Sertralin Actavis, Sertraline Accord, Sertraline Medreg, Zoloft
- Slovenia
- Asentra, Sertralin Krka, Zoloft
- Spain
- Altisben, Aremis, Besitran, Semonic, Sertralina Accord, Sertralina Almus, Sertralina Alter, Sertralina Aurovitas, Sertralina Cinfa, Sertralina Cuve, Sertralina Davur, Sertralina Kern Pharma, Sertralina Mabo, Sertralina Normon, Sertralina Pensa, Sertralina Pharma Combix, Sertralina Qualigen Farma, Sertralina Sandoz Farmacéutica, Sertralina Stada, Sertralina Sun, Sertralina Tarbis Farma, Sertralina Tecnigen, Sertralina Teva-Ratio, Sertralina Viatris, Sertralina Vir-Pharma
- Sweden
- Oralin, Seromeg, Sertralet, Sertralin Amarox, Sertralin Bluefish, Sertralin Hexal, Sertralin Krka, Sertralin Ratiopharm, Sertralin Sun, Sertralin Teva, Sertralin Viatris, Sertralin Zentiva, Sertraline Accord, Sertraline Medical Valley, Sertraline Orifarm, Sertraline Sun, Sertramyl, Sertranat, Sertrone, Serunato, Setaloft, Zoloft
EMA – Article 57 product data (EU/EEA), 2026-10-28
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Sources
- U.S. Food and Drug Administration. Sertraline Hydrochloride (Lupin Pharmaceuticals, Inc.) – Prescribing Information, 2025-10-14. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=42120ff8-b353-4632-9ea9-54de9a698724
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
- Wikidata (CC0): ATC N06AB.
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.