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pregabalin

Lyrica, Pregabalin Viatris Pharma (previously Pregabalin Pfizer) · ATC code N02BF02

Brand names: Lyrica, Pregabalin Viatris Pharma, Lynagex, Lyribastad, Pregabalin Grindeks, Pregabalin Krka, Pregabalin Ratiopharm, Pregabalin Reddy, Pregamid, Pregatab, Pregabador, Pregabahexal, Pregabin, Agapal, Alyse …

Key facts
Active substance
pregabalin
ATC code
N02BF02
Authorisation
centrally authorised across the EU (EMA)
Dosage forms
Lyrica 25 mg hard capsules / Lyrica 50 mg hard capsules / Lyrica 75 mg hard capsules · Lyrica 20 mg/mL oral solution · Lyrica 25 mg orodispersible tablets / Lyrica 75 mg orodispersible tablets / Lyrica 150 mg orodispersible tablets · Pregabalin Viatris Pharma 25 mg hard capsules / Pregabalin Viatris Pharma 50 mg hard capsules / Pregabalin Viatris Pharma 75 mg hard capsules
Marketing authorisation holder
Viatris EESV, Viatris Healthcare Limited
Information as of
2026-10-27

Key facts

Pregabalin is an antiepileptic also used for neuropathic pain and anxiety. In adults it is authorised for neuropathic pain, partial seizures (adjunctive therapy) and generalised anxiety disorder.

What it is used for

  • Peripheral and central neuropathic pain in adults
  • Adjunctive therapy of partial seizures with or without secondary generalisation in adults
  • Generalised anxiety disorder in adults

Dosing

  • Dose range 150 to 600 mg per day in two or three divided doses
  • Neuropathic pain: start 150 mg/day, may increase to 300 mg/day after 3 to 7 days and to a maximum of 600 mg/day after a further 7 days
  • Epilepsy: start 150 mg/day, may increase to 300 mg/day after 1 week, maximum 600 mg/day after an additional week
  • GAD: start 150 mg/day, weekly increases via 300 and 450 mg to a maximum of 600 mg/day; need for treatment reassessed regularly
  • Renal impairment: dose reduced according to creatinine clearance; supplementary dose after each haemodialysis (table in the full text)
  • Discontinue gradually over a minimum of 1 week

Contraindications

  • Hypersensitivity to the active substance or any excipient

Important warnings

  • Misuse, abuse, dependence and withdrawal symptoms after discontinuation, also at therapeutic doses
  • Severe respiratory depression, particularly with compromised respiratory function, renal impairment, concomitant CNS depressants and in the elderly
  • Caution with opioids (CNS depression, increased risk of opioid-related death)
  • Dizziness and somnolence with risk of falls in the elderly; loss of consciousness and confusion reported
  • Suicidal ideation and behaviour
  • Angioedema and severe cutaneous reactions (SJS, TEN); congestive heart failure in elderly cardiovascular-compromised patients

Side effects

  • Most common: dizziness and somnolence, usually mild to moderate
  • CNS adverse reactions increased in central neuropathic pain due to spinal cord injury
  • Rare but serious: Stevens-Johnson syndrome, toxic epidermal necrolysis; encephalopathy reported

Interactions

  • Pharmacokinetic interactions unlikely, as it is mainly excreted unchanged in urine
  • May potentiate the effects of ethanol and lorazepam
  • Opioids and other CNS depressants: reports of respiratory failure, coma and deaths; additive impairment with oxycodone

Pregnancy and breastfeeding

  • Use in the first trimester may cause major birth defects; only if the benefit clearly outweighs the risk, effective contraception required
  • Pregabalin is excreted into human milk; breast-feeding versus therapy must be weighed

Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

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For patients

Package leaflet, verbatim

Package leaflet for patients →

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

EU – centrally authorised (all member states)

Source: European Medicines Agency (EMA), product information

Austria

  • LynagexExeltis Germany Gmbh · 3 register entries
  • LyribastadStada Arzneimittel Gmbh · 1 register entry
  • Pregabalin GrindeksGrindeks · 1 register entry
  • Pregabalin KrkaKrka, D.D., Novo Mesto · 1 register entry
  • Pregabalin RatiopharmTeva B.V · 1 register entry
  • Pregabalin ReddyReddy Holding Gmbh · 1 register entry
  • PregamidG.L. Pharma Gmbh · 1 register entry
  • PregatabNeuraxpharm Arzneimittel Gmbh · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Germany

  • PregabadorTad Pharma Gmbh · 1 register entry
  • PregabahexalHexal Ag · 1 register entry
  • Pregabalin089pharm Gmbh, 1 A Pharma Gmbh, Genmed Pharma Gmbh, Aristo Pharma Gmbh (Art 57), Neuraxpharm Arzneimittel Gmbh, Micro Labs Gmbh, Ratiopharm Gmbh, Puren Pharma Gmbh & Co. Kg, Medical Valley Invest Ab, Glenmark Arzneimittel Gmbh, Jubilant Pharmaceuticals Nv, Heumann Pharma Gmbh & Co. Generica Kg, Vivanta Generics S.R.O., Amarox Pharma Gmbh, Ascend Gmbh, Basics Gmbh, Acino Ag, Biomo Pharma Gmbh, Stadapharm Gmbh, Betapharm Arzneimittel Gmbh, Day Zero Ehf, Denk Pharma Gmbh & Co. Kg, Tad Pharma Gmbh, Abz-Pharma Gmbh, Aliud Pharma Gmbh · 29 register entries
  • PregabinHeumann Pharma Gmbh & Co. Generica Kg · 1 register entry
  • PregatabNeuraxpharm Arzneimittel Gmbh · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Turkey

  • AgapalADVANCE İLAÇ A.Ş. · 3 register entries
  • AlyseABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 9 register entries
  • Gabaday SRCELTİS İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
  • GabaleneTURGUT İLAÇLARI A.Ş. · 4 register entries
  • GalaraWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 12 register entries
  • GebbraNEUTEC İLAÇ SAN. TİC. A.Ş · 9 register entries
  • GericaGENVEON İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
  • GertoreBEK PHARMA ECZA DEPOSU TİC. VE SAN. LTD. ŞTİ. · 9 register entries
  • LypreBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 8 register entries
  • LyricaVİATRİS İLAÇLARI LİMİTED ŞİRKETİ · 10 register entries
  • MaropanASET İLAÇ SAN. VE TİC. A.Ş. · 6 register entries
  • NeogabaMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 8 register entries
Show all 28 brand names
  • NeuricaKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 4 register entries
  • NorafitNEUTEC İLAÇ SAN. TİC. A.Ş · 12 register entries
  • PadenBİLİM İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • PagadinDİNÇSA İLAÇ SAN. VE TİC. A.Ş. · 7 register entries
  • PagamaxNOBEL İLAÇ PAZARLAMA VE SAN. LTD. ŞTİ. · 4 register entries
  • PergeALİ RAİF İLAÇ SAN. A.Ş. · 10 register entries
  • PigusSANDOZ İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
  • PrecobalBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • PrelicaHUMANİS SAĞLIK A.Ş. · 9 register entries
  • PretawTAWALU PHARMA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • RegapenİLKO İLAÇ SAN.VE TİC. A.Ş. · 8 register entries
  • RegobolDR. SERTUS İLAÇ SAN. VE TİC. LTD. ŞTİ. · 3 register entries
  • SnaplineTEVA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • SymraSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 9 register entries
  • ToriaTRIPHARMA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • ZageraPHARMAPLACE İLAÇ TİC. A.Ş. · 3 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

Brand names in 28 more European countries
Belgium
Lynagex, Pregabalin Ab, Pregabalin Grindeks, Pregabaline Eg, Pregabaline Eurogenerics, Pregabaline Krka, Pregabaline Teva
Bulgaria
Pregabin, Бриека, Линефор, Прагиола, Прегабалин Гриндекс, Прегабин, Принципо, Сиранален
Croatia
Pragiola, Pregabalin Belupo, Pregabalin Genericon, Pregabalin Grindeks, Pregabalin Pliva, Siranalen
Cyprus
Epibal, Grabilen, Pragiola, Pregabalin Adalvo, Pregabalin Remedica, Siranalen
Czechia
Kartesada, Naxalgan, Pentegin, Pragiola, Preato, Pregabalin Medreg, Pregabalin Stada Arzneimittel Ag, Pregabalin Teva, Pregabalin Vivanta, Pregamid, Preglenix, Prelica, Siranalen
Denmark
Galberin, Lyribastad, Lyristad, Pregabalin Grindeks, Pregabalin Krka, Pregabalin Medical Valley, Pregabalin Opko Health Spain, Pregabalin Oresund Pharma, Pregabalin Teva, Pregabalin ”teva”, Pregacam, Prelynca
Estonia
Brieka, Bulgaplin, Pragiola, Pregabalin Accord Healthcare, Pregabalin Grindeks, Pregabalin Remedica, Pregamid, Siranalen
Finland
Lyribastad, Pregabalin Grindeks, Pregabalin Krka, Pregabalin Orion, Pregabalin Ratiopharm
France
Lexenu, Nelypra, Pregabalin Grindeks, Pregabaline Arrow, Pregabaline Bgr, Pregabaline Biogaran, Pregabaline Cristers, Pregabaline Eg Labo, Pregabaline Evolugen Pharma, Pregabaline Grindeks, Pregabaline Hcs, Pregabaline Teva, Pregabaline Upsa, Pregabaline Zydus
Greece
Algecia, Apregalin, Brieka, Krelin, Lygabrin, Pagano, Pragiola, Prebanel, Pregabalin Grindeks, Preganet, Prelynca, Siranalen
Hungary
Kartesada, Naxalgan, Prabegin, Pragiola, Pregabalin Orion Pharma, Pregabalin Richter, Pregabalin Stada Arzneimittel, Pregabalin Teva, Pregabalin Vivanta, Pregamid, Prenudol
Iceland
Brieka, Lyrica, Pregabalin
Ireland
Pregabalin Basics, Pregabalin Brillpharma (Ireland), Pregabalin Chanelle Medical, Pregabalin Clomnel, Pregabalin Clonmel, Pregabalin Grindeks, Pregabalin Krka, Pregabalin Pinewood Laboratories, Pregabalin Teva
Italy
Aclaton, Ecubalin, Gabex, Gaviria, Kapdolen, Lindone, Pregabalin Alter, Pregabalin Aurobindo, Pregabalin Doc Generici, Pregabalin Eg Stada Italia, Pregabalin Hcs, Pregabalin Medreg, Pregabalin Pensa Pharma, Pregabalin Tecnigen, Pregabalin Teva Italia, Pregenaq, Prelynca, Regalbax, Rumbot, Serranov
Latvia
Brieka, Bulgaplin, Linefor, Pragiola, Pregabalin Grindeks, Pregamid, Siranalen
Liechtenstein
Lyrica, Pregabalin Accord, Pregabalin Sandoz, Pregabalin Viatris, Pregabalin Zentiva
Lithuania
Brieka, Bulgaplin, Linefor, Pragiola, Pregabalin Grindeks, Pregabalin Remedica, Pregamid
Luxembourg
Pregabalin Micro Labs, Pregabaline Eg
Malta
Pragiola, Pregabalin Adalvo, Pregabalin Clonmel, Pregabalin Remedica, Siranalen
Netherlands
Dalingo, Linefor, Lynagex, Preato, Pregabalin Aurobindo, Pregabalin Oresund Pharma, Pregabalin Retard Aristo, Pregabaline Amarox, Pregabaline Brillpharma, Pregabaline Cnx, Pregabaline Grindeks, Pregabaline Indoco, Pregabaline Krka, Pregabaline Pinewood Laboratories, Pregabaline Reddy, Pregabaline Retard Aristo, Pregabaline Sun, Pregabaline Teva, Pregabaline Vivanta, Pregabline Brill, Pregamid, Siranalen
Norway
Lyrica, Pregabalin
Poland
Bulgaplin, Egzysta, Kartesada, Linefor, Lynagex Xr, Naxalgan, Pentegin, Pragiola, Preato, Pregabalin Aurovitas, Pregabalin Medreg, Pregabalin Pharmalab, Pregamid, Tabagine
Portugal
Kartesada, Lygabrin, Pregabalina, Sindocron, Siranalen, Strymix
Romania
Lynagex, Pragiola, Pregabalină Grindeks, Pregabalină Terapia, Pregabalină Vivanta, Siranalen
Slovakia
Kartesada, Naxalgan, Pentegin, Pragiola, Preato, Pregabalin, Pregamid, Siranalen
Slovenia
Pragiola, Pregabalin Grindeks, Pregabalin Krka, Pregabalin Stada Arzneimittel, Siranalen
Spain
Aciryl, Apregia, Dalingo, Gática, Pramep, Pregabalin Grindeks, Pregabalina, Premax, Trepixal
Sweden
Brieka, Bulgaplin, Lyribastad, Pregabalin

EMA – Article 57 product data (EU/EEA), 2026-10-28

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Sources

  1. European Medicines Agency. Lyrica – EPAR, Product Information (OF THE TEXT Detailed information on this medicinal product i). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/lyrica-epar-product-information_en.pdf
  2. European Medicines Agency. Pregabalin Viatris Pharma (previously Pregabalin Pfizer) – EPAR, Product Information (OF THE TEXT Detailed information on this medicinal product i). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/pregabalin-viatris-pharma-epar-product-information_en.pdf
  3. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  5. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85

Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error

Source: European Medicines Agency (EMA), product information. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.