Methylprednisolone
Solu-Medrol, Urbason · ATC code H02AB04
Also known as: Methylprednisolon, metilprednizolon · Brand names: Solu-Medrol, Urbason, Methylprednisolon Ace Pharmaceuticals, Methylprednisolon Hikma, Methylprednisolon Jenapharm, Metypred, Metysolon, Cortipol, Depo-Medrol, Meticure, Precort, Predlocort, Prednol, Tredison, Medrol …
- Key facts
- Active substance
- Methylprednisolone
- Drug class
- Glucocorticoid
- ATC code
- H02AB04
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-27
Key facts
Methylprednisolone is a systemic glucocorticoid. Per the US prescribing information, the tablets are used for endocrine, rheumatic, collagen, dermatologic and allergic disorders and other inflammatory conditions.
What it is used for
- Endocrine disorders, e.g., adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with cancer
- Rheumatic disorders as short-term adjunctive therapy, e.g., rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis
- Collagen diseases, e.g., systemic lupus erythematosus, dermatomyositis
- Severe dermatologic diseases, e.g., pemphigus, severe erythema multiforme, severe psoriasis
- Severe allergic conditions intractable to conventional treatment; further indications in the full text
Dosing
- Initial dosage 4 mg to 48 mg per day depending on the disease; individualised
- After response, decrease in small steps to the lowest effective maintenance dose
- After long-term therapy, withdraw gradually rather than abruptly
- Stressful situations may require a temporary dose increase
- Alternate day therapy (twice the daily dose every other morning) is an option for long-term treatment; further regimens in the full text
Contraindications
- Systemic fungal infections
- Known hypersensitivity to components
Important warnings
- Immunosuppression: increased risk of infection with any pathogen, which can be severe or fatal; signs of infection may be masked
- Reactivation of latent tuberculosis; chemoprophylaxis during prolonged therapy
- Varicella and measles may be severe
- Under unusual stress, increased dosage of rapidly acting corticosteroids before, during and after
Side effects
- Sodium and fluid retention, hypertension, potassium loss
- Muscle weakness, steroid myopathy, osteoporosis, tendon rupture, aseptic necrosis of femoral and humeral heads
- Peptic ulcer with possible perforation and hemorrhage, pancreatitis
- Cushingoid state, growth suppression in children, adrenal unresponsiveness under stress, decreased carbohydrate tolerance
- Impaired wound healing, thin fragile skin, convulsions, pseudotumor cerebri
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
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For patients
Patient information (US)
This product has no separate US patient information.
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- Solu-MedrolPfizer Corporation Austria Ges.M.B.H. · 1 register entry
- UrbasonFidia Farmaceutici S.P.A · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- Methylprednisolon Ace PharmaceuticalsAce Pharmaceuticals Bv · 1 register entry
- Methylprednisolon HikmaHikma Farmacêutica (Portugal), S.A. · 1 register entry
- Methylprednisolon JenapharmMibe Gmbh Arzneimittel · 1 register entry
- MetypredGalenpharma Gmbh · 3 register entries
- MetysolonMibe Gmbh Arzneimittel · 2 register entries
- UrbasonFidia Farmaceutici S.P.A · 3 register entries
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- CortipolPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- Depo-MedrolPFİZER PFE İLAÇLARI A.Ş. · 1 register entry
- MeticureVEM İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- PrecortKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 5 register entries
- PredlocortSABA İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- PrednolGENSENTA İLAÇ SANAYİ VE TİC. A.Ş. · 13 register entries
- TredisonHAVER TRAKYA İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
USA
- Depo-MedrolPharmacia & Upjohn Company LLC · 8 register entries
- MedrolPharmacia & Upjohn Company LLC · 1 register entry
- Solu-MedrolProPharma Distribution, Medical Purchasing Solutions, LLC, Pharmacia & Upjohn Company LLC · 14 register entries
- Solu-Medrol(r) Methylprednisolone Sodium Succinat1 register entry
Source: U.S. FDA – Drug labels (openFDA/DailyMed), as of 2026-10-28
Brand names in 27 more European countries
- Belgium
- Depo-Medrol, Medrol, Methylprednisolon Ace Pharmaceuticals, Solu-Medrol
- Bulgaria
- Депо-Медрол, Кортаметил, Лисаметил, Медрол, Метилпреднизолон Ромфарм, Метилпреднизолон Софарма, Метилпреднизолон Фармак, Метилпреднизолон Чайкафарма, Софазолон
- Croatia
- Depo-Medrol, Medrol, Solu-Medrol
- Cyprus
- Medrol, Methylprednisolone Kent Pharma Uk, Solu-Medrone
- Czechia
- Depo-Medrol, Medrol, Metypred, Solu-Medrol
- Denmark
- Depo-Medrol, Medrol, Methylprednisolone Orion, Solu-Medrol
- Estonia
- Depo-Medrol, Medrol, Solu-Medrol
- Finland
- Depo-Medrol, Medrol, Metypred, Solomet, Solu-Medrol
- France
- Depo-Medrol, Medrol, Methylprednisolone Hikma
- Greece
- Lyo-Drol, Medrol, Provist
- Hungary
- Depo-Medrol, Medrol, Methylprednisolone Sopharma, Metilprednizolon Teva, Metypred, Solu-Medrol
- Iceland
- Depo-Medrol, Solu-Medrol
- Ireland
- Depo-Medrone, Solu-Medrone
- Italy
- Cortrium, Depo Medrol, Lisamethyle, Medrol, Metildrol, Metilprednisolone Doc, Metilprednisolone Eg, Metilprednisolone Hikma, Metilprednisolone Orion, Metilprednisolone Skin Care, Solu Medrol, Urbason
- Latvia
- Medrol, Solu-Medrol
- Lithuania
- Medrol, Methylprednisolone Sopharma, Metypred, Solu-Medrol
- Luxembourg
- Depo-Medrol, Medrol, Solu-Medrol
- Malta
- Depo-Medrone, Lyo-Drol
- Netherlands
- Depo-Medrol, Methylprednisolon Ace, Solu-Medrol
- Norway
- Depo-Medrol, Medrol, Methylprednisolone Orion, Solu-Medrol
- Poland
- Depo-Medrol, Medrol, Meprelon, Methylprednisolone Sopharma, Metypred, Solu-Medrol
- Portugal
- Depo-Medrol, Medrol, Metilprednisolona Hikma, Metilprednisolona Orion, Solu-Medrol
- Romania
- Lemod Solu, Medrol, Metilprednisolon Rompharm
- Slovakia
- Depo-Medrol, Medrol, Metylprednizolón Hikma, Metypred, Solu-Medrol
- Slovenia
- Depo-Medrol, Medrol
- Spain
- Metilprednisolona Normon, Metilprednisolona Orion, Solu-Moderín, Urbason
- Sweden
- Depo-Medrol, Medrol, Methylprednisolone Orion, Solu-Medrol
EMA – Article 57 product data (EU/EEA), 2026-10-28
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Sources
- U.S. Food and Drug Administration. Methylprednisolone (Mylan Pharmaceuticals Inc.) – Prescribing Information, 2026-06-22. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=22dd75d6-f89a-44f7-8ca6-b64c4e9806dd
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
- U.S. FDA – Drug labels (openFDA/DailyMed), 2026-10-28. https://dailymed.nlm.nih.gov/dailymed/
- Wikidata (CC0): ATC H02AB.
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.