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lacosamide

Lacosamide UCB, Vimpat · ATC code N03AX18

Also known as: Lacosamid · Brand names: Lacosamide UCB, Vimpat, Lacopat, Lacosamid Fresenius Kabi, Lacosamid Grindeks, Lacosamid Hameln, Lacosamid Hikma, Lacosamid Tillomed, Filmtabletten, Kanilad, Lackepila, Lacosabil, Trelema, Benvida, Elepsi …

Key facts
Active substance
lacosamide
Drug class
Anticonvulsant agent
ATC code
N03AX18
Authorisation
centrally authorised across the EU (EMA)
Dosage forms
Lacosamide UCB 50 mg film-coated tablets / Lacosamide UCB 100 mg film-coated tablets / Lacosamide UCB 150 mg film-coated tablets · Treatment initiation pack (in adolescents and children weighing 50 kg or more and adults only) / Lacosamide UCB 50 mg film-coated tablets / Lacosamide UCB 100 mg film-coated tablets · Lacosamide UCB 10 mg/ml syrup · Lacosamide UCB 10 mg/ml solution for infusion · Vimpat 50 mg film-coated tablets / Vimpat 100 mg film-coated tablets / Vimpat 150 mg film-coated tablets · Treatment initiation pack (in adolescents and children weighing 50 kg or more and adults only) / Vimpat 50 mg film-coated tablets / Vimpat 100 mg film-coated tablets · Vimpat 10 mg/ml syrup · Vimpat 10 mg/ml solution for infusion
Marketing authorisation holder
UCB Pharma S.A., UCB Pharma SA
Information as of
2026-10-27

Key facts

Lacosamide is an antiepileptic medicine. It is used in epilepsy for partial-onset seizures and as add-on therapy for primary generalised tonic-clonic seizures (tablets, syrup, solution for infusion).

What it is used for

  • Monotherapy of partial-onset seizures with or without secondary generalisation in adults, adolescents and children from 2 years
  • Adjunctive therapy of partial-onset seizures from 2 years
  • Adjunctive therapy of primary generalised tonic-clonic seizures in idiopathic generalised epilepsy from 4 years

Dosing

  • Taken twice a day, approximately 12 hours apart
  • 50 kg or more and adults, monotherapy: start 50 mg twice a day, after one week 100 mg twice a day; weekly increases up to 300 mg twice a day
  • 50 kg or more and adults, adjunctive: start 50 mg twice a day, after one week 100 mg twice a day; maximum 200 mg twice a day
  • Alternatively a 200 mg loading dose followed by 100 mg twice a day, under medical supervision
  • Children under 50 kg: start 1 mg/kg twice a day, weight-based maximum doses; syrup preferred
  • Take a missed dose at once unless the next one is due within 6 hours; never a double dose

Contraindications

  • Hypersensitivity to the active substance or any excipient
  • Known second- or third-degree atrioventricular (AV) block

Important warnings

  • Suicidal ideation and behaviour: monitor for signs
  • Dose-related PR prolongation; caution in conduction problems, severe cardiac disease, the elderly and with drugs affecting cardiac conduction
  • After a loading dose, possible higher incidence of serious cardiac arrhythmia and CNS adverse reactions
  • Dizziness may increase the risk of accidental injury or falls

Side effects

  • Most frequent (≥ 10%): dizziness, headache, nausea, diplopia
  • Usually mild to moderate, some dose-related; CNS and GI reactions usually decreased over time
  • Dizziness was the most common reason for discontinuation

Interactions

  • Caution with drugs that prolong the PR interval (including sodium channel blocking antiepileptics) and with antiarrhythmics
  • Generally low interaction potential; CYP2C9, CYP2C19 and CYP3A4 form the O-desmethyl metabolite

Pregnancy and breastfeeding

  • Discuss family planning and contraception with women of childbearing potential; re-evaluate use carefully if pregnancy is planned

Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

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For patients

Package leaflet, verbatim

Package leaflet for patients →

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

EU – centrally authorised (all member states)

Source: European Medicines Agency (EMA), product information

Austria

  • LacopatG.L. Pharma Gmbh · 3 register entries
  • Lacosamid Fresenius KabiFresenius Kabi Austria Gmbh · 1 register entry
  • Lacosamid GrindeksGrindeks · 1 register entry
  • Lacosamid HamelnHameln Pharma Gmbh · 2 register entries
  • Lacosamid HikmaHikma Farmacêutica (Portugal), S.A. · 1 register entry
  • Lacosamid TillomedTillomed Malta Ltd · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Germany

  • FilmtablettenDesitin Arzneimittel Gmbh · 1 register entry
  • KaniladMedochemie Ltd. · 1 register entry
  • LackepilaAxunio Pharma Gmbh · 1 register entry
  • LacosabilTad Pharma Gmbh · 1 register entry
  • LacosamidHexal Ag, 1 A Pharma Gmbh, 123 Acurae Pharma Gmbh, Fresenius Kabi Deutschland Gmbh, Neuraxpharm Arzneimittel Gmbh, Aaa-Pharma Gmbh, Ratiopharm Gmbh, Medical Valley Invest Ab, Glenmark Pharmaceuticals S.R.O., Hormosan Pharma Gmbh, Jubilant Pharmaceuticals Nv, Macleods Pharma España, S.L.U, Tillomed Malta Ltd, Desitin Arzneimittel Gmbh, Heumann Pharma Gmbh & Co. Generica Kg, Vivanta Generics S.R.O., Zentiva Pharma Gmbh, Amarox Pharma Gmbh, Aristo Pharma Gmbh (Art 57), Ascend Gmbh, Hameln Pharma Gmbh, Hikma Farmacêutica (Portugal), S.A., Intas Third Party Sales 2005, S.L., Viatris Germany Gmbh, Olpha As, Eugia Pharma (Malta) Limited, Puren Pharma Gmbh & Co. Kg, Stadapharm Gmbh, Betapharm Arzneimittel Gmbh, Abz-Pharma Gmbh, Aliud Pharma Gmbh · 35 register entries
  • TrelemaG.L. Pharma Gmbh · 3 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Turkey

  • BenvidaUCB PHARMA A.Ş. · 5 register entries
  • ElepsiSANTA FARMA İLAÇ SAN. A.Ş. · 6 register entries
  • LamideALİ RAİF İLAÇ SAN. A.Ş. · 6 register entries
  • MatisseSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 4 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

Brand names in 28 more European countries
Belgium
Lacosamid Hikma, Lacosamide Eg, Lacosamide Grindeks, Lacosamide Hikma, Lacosamide Krka, Lacosamide Sandoz
Bulgaria
Канилад, Лакозамид Гриндекс, Лосморид, Трелема
Croatia
Kanilad, Lacosamide Grindeks, Lakozamid Grindeks, Lakozamid Pliva, Losmorid, Midza
Cyprus
Kanilad, Lacosadel, Lacosamide Genepharm
Czechia
Arkvimma, Kanilad, Lacosamide Fresenius Kabi, Lacosamide Glenmark, Lacosamide Grindeks, Lacosamide Sandoz, Lacosamide Zentiva, Lakosamid +pharma, Laramo, Trelema
Denmark
200, Lacosamid Opko Health Spain, Lacosamid Viatris, Lacosamide
Estonia
Kanilad, Lacosamide Alembic, Lacosamide Fresenius Kabi, Lacosamide Grindeks, Lacosamide Tablets, Lacosamide Teva
Finland
Lacosamide Fresenius Kabi, Lacosamide Grindeks, Lacosamide Hameln, Lacosamide Medical Valley, Lacosamide Stada, Lacosamide Strides, Lacosamide Tillomed, Lacosamide Vivanta, Trelema
France
Lacosamide Arrow, Lacosamide Biogaran, Lacosamide Eg, Lacosamide Fresenius Kabi, Lacosamide G.L Pharma, Lacosamide G.L. Pharma, Lacosamide Grindeks, Lacosamide Hameln, Lacosamide Hikma, Lacosamide Olpha, Lacosamide Sandoz, Lacosamide Stragen, Lacosamide Teva, Lacosamide Tillomed, Lacosamide Viatris, Lacosamide Vivanta, Lacosamide Zentiva, Lacosamide Zydus
Greece
Anlamyl, Josamec, Kanilad, Lacosamide Anfarm, Lacosamide Genepharm, Lacosamide Grindeks, Lacosamide Teva, Seizpat
Hungary
Anlamyl, Arkvimma, Cosim, Lacosamid Teva, Lacosamide Anfarm, Lacosamide Fresenius Kabi, Lacosamide Genepharm, Lacosamide Grindeks, Losmorid, Trelema
Iceland
Josamec, Lacosamide Accord, Lacosamide Doc, Lacosamide Krka, Lacosamide Medical Valley, Lacosamide Stada, Lacosamide Treatment Initiation Pack (In Adolescent And Children Weighing, Lacosamide Ucb, Vimpat
Ireland
Lacosamide Ascend, Lacosamide Fresenius Kabi, Lacosamide Grindeks, Lacosamide Krka, Lacosamide Neuraxpharm
Italy
Lacosamide Aurobindo, Lacosamide Doc, Lacosamide Dr. Reddy’s, Lacosamide Eg, Lacosamide Eugia, Lacosamide Fresenius Kabi, Lacosamide Hameln, Lacosamide Hikma, Lacosamide Krka, Lacosamide Mylan, Lacosamide Olpha, Lacosamide Sandoz, Lacosamide Tecnigen, Lacosamide Teva, Lacosamide Tillomed, Lacosamide Vivanta, Lacosamide Zentiva, Laprysta, Nepilex, Ollat, Stutan
Latvia
Kanilad, Lacosamide Fresenius Kabi, Lacosamide Grindeks, Lacosamide Olpha, Lacosamide Teva
Liechtenstein
Lacosamid Fresenius Kabi, Lacosamide Accord, Lacosamide Treatment Initiation Pack (In Adolescent And Children Weighing, Lacosamide Ucb, Vimpat
Lithuania
Lacosamide Fresenius Kabi, Lacosamide Grindeks
Luxembourg
Lacosamide Eg
Malta
Anlamyl, Kanilad, Lacosamide Anfarm, Lacosamide Aurobindo, Lacosamide Fresenius Kabi
Netherlands
Cosim, Lacosamide Amarox, Lacosamide Aristo, Lacosamide Aurobindo, Lacosamide Glenmark, Lacosamide Grindeks, Lacosamide Hameln, Lacosamide Hikma, Lacosamide Neuraxpharm, Lacosamide Sandoz, Lacosamide Stada, Lacosamide Teva, Lacosamide Viatris, Lacosamide Vivanta, Lacosamide Xiromed
Norway
Lacosamide Accord, Lacosamide Fresenius Kabi, Lacosamide Grindeks, Lacosamide Hameln, Lacosamide Krka, Lacosamide Medical Valley, Lacosamide Strides, Lacosamide Tillomed, Lacosamide Treatment Initiation Pack (In Adolescent And Children Weighing, Lacosamide Ucb, Lacosamide Vivanta, Vimpat
Poland
Arkvimma, Epilantin, Lackepila, Lacosamide Fresenius Kabi, Lacosamide Neuraxpharm, Lacosamide Teva, Trelema
Portugal
Lacosamida Alter, Lacosamida Aristo, Lacosamida Eugia, Lacosamida Farmoz, Lacosamida Fresenius Kabi, Lacosamida Generis, Lacosamida Hikma, Lacosamida Intas, Lacosamida Jubilant Pharmaceuticals, Lacosamida Mylan, Lacosamida Pentafarma, Lacosamida Ratiopharm, Lacosamida Zentiva, Lacosamide
Romania
Lacosamidă Teva
Slovakia
Arkvimma, Kanilad, Lacosamide Fresenius Kabi, Lacosamide Grindeks, Midza, Seizpat, Trelema
Slovenia
Lacosabil, Lacosamide Grindeks, Lakozamid Grindeks, Lakozamid Hcs, Lakozamid Teva, Losmorid, Lydraso
Spain
Balmid, Kanilad, Lacosamida, Laprysta, Lydraso, Nexilina, Vilepsia, Vitelax
Sweden
Lacomed, Lacosamide, Lakosamid Amarox, Trelema

EMA – Article 57 product data (EU/EEA), 2026-10-28

Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.

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Sources

  1. European Medicines Agency. Lacosamide UCB – EPAR, Product Information (OF THE TEXT Detailed information on this medicine is availab). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/lacosamide-ucb-epar-product-information_en.pdf
  2. European Medicines Agency. Vimpat – EPAR, Product Information (OF THE TEXT Detailed information on this medicine is availab). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/vimpat-epar-product-information_en.pdf
  3. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  5. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
  6. Wikidata (CC0): ATC N03AX.

Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error

Source: European Medicines Agency (EMA), product information. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.