Fluconazole
Diflucan, Difluzol, Fluconazol, Fluconazole Ratiopharm · ATC code J02AC01
Also known as: Fluconazol, Flukonazol · Brand names: Diflucan, Difluzol, Fluconazole Ratiopharm, Flucosept, Flucoderm, Flunazul, Fungata, Mycosyst, Candidin, Candiflu, Candimax, Candinazol, Candisept, Canzolix, Flucan …
- Key facts
- Active substance
- Fluconazole
- ATC code
- J02AC01
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-27
Key facts
Fluconazole is an azole antifungal. Per this US label (tablets), it is used for vaginal, oropharyngeal and esophageal candidiasis, cryptococcal meningitis, and candidiasis prophylaxis in bone marrow transplantation.
What it is used for
- Vaginal candidiasis
- Oropharyngeal and esophageal candidiasis; also Candida urinary tract infections, peritonitis and systemic Candida infections
- Cryptococcal meningitis
- Prophylaxis: decreasing candidiasis in bone marrow transplant patients receiving chemotherapy and/or radiation
Dosing
- Vaginal candidiasis: 150 mg as a single oral dose
- Oropharyngeal candidiasis: 200 mg on the first day, then 100 mg once daily for at least 2 weeks
- Esophageal candidiasis: 200 mg on the first day, then 100 mg daily (up to 400 mg/day); minimum three weeks
- Acute cryptococcal meningitis: 400 mg on the first day, then 200 mg once daily; relapse suppression in AIDS 200 mg once daily
- Renal impairment with multiple doses: creatinine clearance ≤ 50 mL/min without dialysis 50% of the dose; hemodialysis: 100% after each dialysis
- Children: weight-based dosing, details in the full text
Contraindications
- Hypersensitivity to fluconazole or any excipient
- Coadministration of QT-prolonging CYP3A4 substrates such as erythromycin, pimozide and quinidine
Important warnings
- Rare serious hepatic toxicity, including fatalities; discontinue if liver disease develops
- Anaphylaxis in rare cases
- Exfoliative skin disorders, some fatal; discontinue if lesions progress
- QT prolongation and torsade de pointes, mostly in seriously ill patients with risk factors
Side effects
- Generally well tolerated
- Single dose for vaginal candidiasis: most common headache (13%), nausea (7%) and abdominal pain (6%)
- Rarely angioedema and anaphylaxis; hepatic, renal and hematological changes seen in seriously ill patients
Interactions
- Sulfonylureas (e.g. glyburide, glipizide, tolbutamide): hypoglycemia possible; monitor blood glucose
- Coumarin-type anticoagulants (warfarin): increased prothrombin time and bleeding; monitor and adjust dose
- Increases levels of phenytoin, cyclosporine, fentanyl and saquinavir; rifampin enhances fluconazole metabolism
- Pimozide, erythromycin, quinidine: contraindicated
Pregnancy and breastfeeding
- Pregnancy: avoid except in severe or life-threatening fungal infections; congenital anomalies reported after high-dose first-trimester exposure
- Nursing: present in low levels in breast milk
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
Common questions – ask Medelix
For patients
Patient information (US)
This product has no separate US patient information.
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- DiflucanPfizer Corporation Austria Ges.M.B.H. · 2 register entries
- DifluzolStada Arzneimittel Gmbh · 1 register entry
- Fluconazol1a Pharma Gmbh, Teva B.V, Actavis Group Ptc Ehf., B.Braun Melsungen Ag, +pharma Arzneimittel Gmbh, Noridem Enterprises Ltd, Hikma Farmacêutica (Portugal), S.A. · 9 register entries
- Fluconazole RatiopharmTeva B.V · 1 register entry
- FlucoseptKwizda Pharma Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- DiflucanPfizer Pharma Gmbh · 4 register entries
- FlucodermDermapharm Ag · 1 register entry
- Fluconazol1 A Pharma Gmbh, Vitabalans Oy, B.Braun Melsungen Ag, Accord Healthcare B.V., Aristo Pharma Gmbh (Art 57), Basics Gmbh, Pfizer Pharma Gmbh, Hexal Ag, Hikma Farmacêutica (Portugal), S.A., Puren Pharma Gmbh & Co. Kg, Stadapharm Gmbh, Denk Pharma Gmbh & Co. Kg, Fresenius Kabi Deutschland Gmbh, Teva Gmbh, Aliud Pharma Gmbh · 18 register entries
- FlunazulDr. Pfleger Arzneimittel Gmbh · 3 register entries
- FungataPfizer Pharma Gmbh · 1 register entry
- MycosystGedeon Richter Plc. · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- CandidinTOPRAK İLAÇ VE KİMYEVİ MADDELER SAN.VE TİC. A.Ş. · 4 register entries
- CandifluTURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş. · 2 register entries
- CandimaxNEUTEC İLAÇ SAN. TİC. A.Ş · 5 register entries
- CandinazolİSTANBUL İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- CandiseptVEM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- CanzolixBERKO İLAÇ VE KİMYA SAN. A.Ş. · 1 register entry
- FlucanPFİZER PFE İLAÇLARI A.Ş. · 10 register entries
- FlucofexFARMA-TEK İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- FlucoralBİLİM İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- FlujectTÜM-EKİP İLAÇ A.Ş. · 2 register entries
- FlukodeksPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- FlukolPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
Show all 25 brand names
- FlukopolPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- FlumasinHAVER TRAKYA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- FlumycoTURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş. · 1 register entry
- FluzamedWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 15 register entries
- FluzoleBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
- FunganMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 5 register entries
- GynoflazolHÜSNÜ ARSAN İLAÇLARI A.Ş. · 2 register entries
- KandizolNOBEL İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- LukoULKAR İLAÇ PAZARLAMA LTD. ŞTİ. · 1 register entry
- Selfleks FlukoselHAVER FARMA İLAÇ A.Ş. · 2 register entries
- TrizolKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 3 register entries
- ZofunolNİNOVA ECZA DEPOSU İTHALAT İHRACAT LTD. ŞTİ. · 1 register entry
- ZolaxSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 10 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
USA
- DiflucanRoerig · 1 register entry
Source: U.S. FDA – Drug labels (openFDA/DailyMed), as of 2026-10-28
Brand names in 27 more European countries
- Belgium
- Diflucan, Fluconazol Ab, Fluconazol Fresenius Kabi, Fluconazole B. Braun, Fluconazole Eg, Fluconazole Sandoz, Fluconazole Teva, Fluconazole Viatris
- Bulgaria
- Exomax, Дифлазон, Дифлукан, Кандизол, Медофлукон, Микомакс, Флузамед, Флуконазол World Medicine Europe Eood, Флукорик, Фунгокап, Фунголон
- Croatia
- Diflucan, Fluconax, Flukonazol Kabi
- Cyprus
- Dilapan, Fluconazole Noridem, Flucozal, Fungustatin, Gynofloran, Medoflucon, Mycozal
- Czechia
- Diflucan, Fluconazol Kabi, Fluconazole Noridem, Fluconazole Vitabalans, Flukonazol Sandoz, Mycomax
- Denmark
- Diflucan, Fluconazol "hexal", Fluconazol Accord, Fluconazol B. Braun, Fluconazol Bluefish, Fluconazol Fresenius Kabi, Fluconazol Krka, Fluconazol Stada, Fluconazol Vitabalans, Fluconazole Noridem
- Estonia
- Diflazon, Diflucan, Fluconazol Baxter, Fluconazole Actavis, Fluconazole Elvim, Fluconazole Medochemie, Fluconazole Sandoz, Fluconazole Teva, Fluconazole Vitabalans, Flunoc
- Finland
- Diflucan, Fluconazol Fresenius Kabi, Fluconazol Krka, Fluconazol Orion, Fluconazol Ratiopharm, Fluconazol Vitabalans, Fluconazole Noridem Enterprises
- France
- Beagyne, Fluconazole Aguettant, Fluconazole Arrow, Fluconazole Biogaran, Fluconazole Cristers, Fluconazole Eg, Fluconazole Evolugen, Fluconazole Kabi, Fluconazole Noridem Enterprises Ltd, Fluconazole Pfizer, Fluconazole Sandoz, Fluconazole Teva, Fluconazole Viatris, Fluconazole Zentiva, Fluconazole Zydus, Orofluco, Triflucan
- Greece
- Afloxol, Azoflu, Azzol-S, Candiflu, Dermaspor, Falipan, Farviron, Flucalit, Flucanid, Flucocaps Therapy, Flucodrug, Flucofin, Fluconazole /Kabi, Fluconazole B. Braun, Fluconazole Noridem, Fluconazole Syndesmos, Fluconazole/Medicus, Flucoran, Flucostatin, Flucovein, Flusenil, Fluzomic, Funadel, Fungo, Fungofort, Fungram, Fungustatin, Fuxilidin, Gynosant, Hadlinol, Medoflucon, Mycazole, Novoflon, Rifagen, Sadlos, Stabilanol, Tierlite, Zidonil
- Hungary
- Dermyc, Diflazon, Diflucan, Flucohexal, Fluconazol Vitabalans, Fluconazole Kabi, Fluconazole Noridem, Fluconazole-Q Pharma, Fluconazole Teva, Fluconer, Intiflor, Mycosyst
- Iceland
- Candizol, Diflucan, Fluconazol Krka, Fluconazole Alvogen, Fungyn
- Ireland
- Caneclear, Canoral, Diflucan, Flucol, Fluconazol Baxter, Fluconazole Accord, Fluconazole B. Braun Melsungen, Fluconazole Noridem Enterprises Limited
- Italy
- Alozof, Aviflucox, Azolix, Azonal, Canacid, Diflucan, Dizolo, Elazor, Fluconazole Ratiopharm, Fluconazolo Abc, Fluconazolo Accord, Fluconazolo Almus, Fluconazolo Aurobindo, Fluconazolo B. Braun, Fluconazolo Bioindustria L.I.M., Fluconazolo Doc Generici, Fluconazolo Eg, Fluconazolo Galenica Senese, Fluconazolo Hexal, Fluconazolo Kabi, Fluconazolo Mylan, Fluconazolo Noridem, Fluconazolo Pensa, Fluconazolo Ratiopharm, Fluconazolo Sandoz, Fluconazolo Tecnigen, Fluconazolo Zentiva, Flukimex, Flumicon, Flumos, Fluores, Fungus, Gemiflux, Klaider, Lefunzol, Lucandiol, Maicox, Miconix, Riflax, Tedim, Trimikos, Winch, Zamizol, Zerfun, Zoloder
- Latvia
- Diflucan, Fluconazole Actavis, Fluconazole Baxter, Fluconazole Elvim, Fluconazole Olpha, Fluconazole Teva, Fluconazole Unifarma, Fluconazole Vitabalans, Mycomax, Mycosyst
- Lithuania
- Diflazon, Diflucan, Fluconazol Baxter, Fluconazole Actavis, Fluconazole Elvim, Fluconazole Ibe, Fluconazole Teva, Fluconazole Vitabalans, Flucoric, Mycomax
- Luxembourg
- Diflucan, Fluconazol Ab, Fluconazol B. Braun, Fluconazol Fresenius Kabi, Fluconazole Eg, Fluconazole Viatris
- Malta
- Flucol, Fluconazole Accord Healthcare, Fluconazole Kabi, Flucozal, Medoflucon
- Netherlands
- Diflucan, Fluconazol Accord, Fluconazol Cf, Fluconazol Fresenius Kabi, Fluconazol Hikma, Fluconazol Noridem, Fluconazol Pharmathen, Fluconazol Sandoz, Fluconazol Teva, Fluconazole Aurobindo
- Norway
- Canesoral, Diflucan, Fluconazol B. Braun, Fluconazol Krka, Fluconazol Vitabalans, Fluconazole Noridem
- Poland
- Candifluc, Diflucan, Flucofast, Fluconazin, Fluconazol Baxter, Fluconazole Aurovitas, Fluconazole B. Braun, Fluconazole Genoptim, Fluconazole Hasco, Fluconazole Kabi, Fluconazole Polfarmex, Fluconazole Pph, Fluconazolum Aflofarm, Flukofemin One, Flukonazol Actavis, Flumycon, Fluxazol, Mycosyst
- Portugal
- Diflucan, Fluconazol Alter, Fluconazol Aurobindo, Fluconazol Aurovitas, Fluconazol Basi, Fluconazol Farmoz, Fluconazol Gedeon Richter, Fluconazol Generis, Fluconazol Hikma, Fluconazol Kabi, Fluconazol Krka, Fluconazol Noridem, Fluconazol Ratiopharm, Fluconazol Sandoz, Fluconazol Strami, Fluconazol Supremase, Fluconazol Tolife, Fluconazol Vitória, Fluconazol Wynn
- Romania
- Diflucan, Fluconazol Arena, Fluconazol Bioeel, Fluconazol Infomed, Fluconazol Kabi, Fluconazol Laropharm, Fluconazol Lph Labormed, Fluconazol Noridem Enterprises, Fluconazol Rompharm, Fluconazol Slavia, Fluconazole Teva, Flucoric, Flucovim, Fluctobar
- Slovakia
- Diflucan, Fluco, Fluconazol Kabi, Fluconazole Noridem, Fluconazole Vitabalans, Medoflucon, Mycomax
- Slovenia
- Diflazon, Diflucan, Flukonazol Baxter, Flukonazol Vitabalans
- Spain
- Candifix, Diflucan, Fluconazol Altan, Fluconazol Aristo, Fluconazol Aurovitas, Fluconazol B. Braun, Fluconazol Cinfa, Fluconazol Combix, Fluconazol Kabi, Fluconazol Kern Pharma, Fluconazol Mabo, Fluconazol Normon, Fluconazol Pharmathen, Fluconazol Qualigen, Fluconazol Sandoz, Fluconazol Stada, Fluconazol Tarbis, Fluconazol Tecnigen, Fluconazol Teva, Fluconazol Viatris, Loitin
- Sweden
- Diflucan, Fluconazol Actavis, Fluconazol Bluefish, Fluconazol Fresenius Kabi, Fluconazol Hexal, Fluconazol Krka, Fluconazol Vitabalans, Fluconazole Accord, Fluconazole B. Braun, Fluconazole Noridem, Fluconazole Teva, Solona
EMA – Article 57 product data (EU/EEA), 2026-10-28
Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.
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Sources
- U.S. Food and Drug Administration. fluconazole (Zydus Pharmaceuticals (USA) Inc.) – Prescribing Information, 2026-04-07. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d1364455-1537-46d4-b093-38cca3be778f
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
- U.S. FDA – Drug labels (openFDA/DailyMed), 2026-10-28. https://dailymed.nlm.nih.gov/dailymed/
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.