Diclofenac
Dedolor Akut, Dedolor Drs, Deflamat, Diclo-Vision Sine · ATC code M01AB05
Also known as: diklofenak, Diclofenac Potassium · Brand names: Dedolor Akut, Dedolor Drs, Deflamat, Diclo-Vision Sine, Diclobene, Diclostad, Kerativena, Mobiflex Akut, Solacutan, Solaraze, Tratul, Voltadol, Voltaren, Arthrex Schmerzgel, Diclac …
- Key facts
- Active substance
- Diclofenac
- ATC code
- M01AB05
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-27
Boxed warning
Cardiovascular Thrombotic Events
- Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use (see WARNINGS).
- Diclofenac potassium tablets are contraindicated in the setting of coronary artery bypass graft (CABG) surgery (see CONTRAINDICATIONS, WARNINGS).
Gastrointestinal Bleeding, Ulceration, and Perforation
- NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events (see WARNINGS).
Key facts
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). Per the US prescribing information (diclofenac potassium tablets), it is used for pain, primary dysmenorrhea, osteoarthritis and rheumatoid arthritis.
What it is used for
- Primary dysmenorrhea
- Mild to moderate pain
- Signs and symptoms of osteoarthritis
- Signs and symptoms of rheumatoid arthritis
Dosing
- Lowest effective dose for the shortest duration.
- Pain or dysmenorrhea: 50 mg three times a day; in some patients an initial 100 mg followed by 50 mg doses.
- Osteoarthritis: 100 to 150 mg/day in divided doses (50 mg twice or three times a day).
- Rheumatoid arthritis: 150 to 200 mg/day in divided doses (50 mg three or four times a day).
- Different diclofenac formulations are not necessarily bioequivalent.
Contraindications
- Known hypersensitivity to diclofenac or components
- History of asthma, urticaria or allergic-type reactions after aspirin or other NSAIDs
- In the setting of coronary artery bypass graft (CABG) surgery
Important warnings
- Boxed warning: increased risk of serious cardiovascular thrombotic events (MI, stroke), which can be fatal
- Boxed warning: increased risk of GI bleeding, ulceration and perforation, which can occur without warning symptoms
- Hepatotoxicity, hypertension, heart failure and edema
- Renal toxicity and hyperkalemia
- Anaphylactic reactions and serious skin reactions; hematologic toxicity
Side effects
- Gastrointestinal: abdominal pain, constipation, diarrhea, dyspepsia, flatulence, heartburn, nausea, vomiting, GI ulcers
- Abnormal renal function, anemia, dizziness, edema, elevated liver enzymes
- Headaches, increased bleeding time, pruritus, rashes, tinnitus
Interactions
- Warfarin and other anticoagulants, antiplatelet agents (e.g. aspirin), SSRIs and SNRIs increase bleeding risk
- Avoid concomitant use with other NSAIDs
Pregnancy and breastfeeding
- Avoid at about 30 weeks gestation and later (premature closure of the fetal ductus arteriosus).
- From about 20 weeks, risk of fetal renal dysfunction with oligohydramnios; diclofenac may be present in human milk.
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
Common questions – ask Medelix
For patients
Patient information (US)
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- Dedolor AkutGlenwood Gmbh · 1 register entry
- Dedolor DrsGlenwood Gmbh · 1 register entry
- DeflamatGlenwood Gmbh · 6 register entries
- Diclo-Vision SineOmnivision Gmbh · 1 register entry
- DiclobeneTeva B.V · 6 register entries
- DiclofenacDermapharm Ag, 1a Pharma Gmbh, Genericon Pharma Gesellschaft M.B.H., S.Med Handelsgmbh, Alfrapharma S.R.L., G.L. Pharma Gmbh, Sandoz Gmbh, Fresenius Kabi Austria Gmbh · 11 register entries
- DiclostadStada Arzneimittel Gmbh · 2 register entries
- KerativenaGlenmark Arzneimittel Gmbh · 1 register entry
- Mobiflex AkutStada Arzneimittel Gmbh · 1 register entry
- SolacutanDermapharm Gmbh · 1 register entry
- SolarazeAlmirall, S.A. · 1 register entry
- TratulG.L. Pharma Gmbh · 2 register entries
Show all 14 brand names
- VoltadolHaleon - Gebro Consumer Health Gmbh · 2 register entries
- VoltarenNovartis Pharma Gmbh, Laboratoires Thea · 7 register entries
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- Arthrex Schmerzgel1 A Pharma Gmbh · 1 register entry
- DiclacHexal Ag · 6 register entries
- DicloDenk Pharma Gmbh & Co. Kg, 1 A Pharma Gmbh, Ratiopharm Gmbh, Glenwood Gmbh, Omnivision Gmbh, Dr. Kade Pharmazeutische Fabrik Gmbh, Teva B.V, Betapharm Arzneimittel Gmbh · 16 register entries
- DicloberlBerlin-Chemie Ag · 2 register entries
- DiclofenacBetapharm Arzneimittel Gmbh, Ratiopharm Gmbh, Fairmed Healthcare Gmbh, Heumann Pharma Gmbh & Co. Generica Kg, Panpharma Gmbh, Micro Labs Gmbh, Farmalider, S.A., Aliud Pharma Gmbh, Glenmark Arzneimittel Gmbh, Devatis Gmbh, Aristo Pharma Gmbh (Art 57), Giuliani Spa, Fidia Farmaceutici S.P.A, Puren Pharma Gmbh & Co. Kg, Stada Consumer Health Deutschland Gmbh, Stadapharm Gmbh, Mibe Gmbh Arzneimittel, Zentiva Pharma Gmbh, Denk Pharma Gmbh & Co. Kg, Abz-Pharma Gmbh · 34 register entries
- DicloklaphAenova Ip Gmbh · 2 register entries
- DiclotinVitabalans Oy · 1 register entry
- Diclowal SuppWalter Ritter Gmbh + Co. Kg · 1 register entry
- Difen UdPharma Stulln Gmbh · 1 register entry
- ItamiFidia Farmaceutici S.P.A · 1 register entry
- ItamioneFidia Farmaceutici S.P.A · 1 register entry
- KeronacKlinge Pharma Gmbh · 1 register entry
Show all 17 brand names
- Olfen PatchTeva B.V · 1 register entry
- Proff Diclo SchmerzgelDolorgiet Gmbh & Co Kg · 1 register entry
- SolacutanDermapharm Ag · 1 register entry
- SolarazeAlmirall, S.A. · 1 register entry
- VoltarenNovartis Pharma Gmbh, Haleon Germany Gmbh, Laboratoires Thea, Kohlpharma Gmbh · 10 register entries
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- ArtenakTURK İLAÇ VE SERUM SAN. A.Ş. · 2 register entries
- BenseriHUMANİS SAĞLIK A.Ş. · 3 register entries
- CataflamNOVARTİS SAĞLIK GIDA VE TARIM ÜRÜNLERİ SAN. VE TİC. A.Ş. · 1 register entry
- ClodifenWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- ClofastAVİXA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- DiclofixCELTİS İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- DicloflamSANTA FARMA İLAÇ SAN. A.Ş. · 2 register entries
- DiclogesicSABA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- DiclomecABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 9 register entries
- DicloponacTRIPHARMA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- DifenakTERRA İLAÇ VE KİMYA SAN. TİC. A.Ş. · 2 register entries
- DifenjectTÜM-EKİP İLAÇ A.Ş. · 3 register entries
Show all 29 brand names
- DiklesFARMALAS İLAÇ SAN. VE TİC. LTD. ŞTİ. · 2 register entries
- DiklojikOSEL İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- DiklopainAVİXA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- DikloronDEVA HOLDİNG A.Ş. · 11 register entries
- DolorexABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- FeoptidinHAVER TRAKYA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- FevereGENSU PHARMA İLAÇ SAN VE TİC LTD ŞTİ · 1 register entry
- KalidrenYAVUZ İLAÇ ECZA DEPOSU MEDİKAL ÜRÜNLER SAN.VE TİC. A.Ş. · 1 register entry
- KatalasFARMALAS İLAÇ SAN. VE TİC. LTD. ŞTİ. · 1 register entry
- Merix SRNOBEL İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- MiyadrenYAVUZ İLAÇ ECZA DEPOSU MEDİKAL ÜRÜNLER SAN.VE TİC. A.Ş. · 8 register entries
- RapidusSANTASYA İLAÇ KOZMETİK MEDİKAL İTRİYAT PAZARLAMA SAĞLIK HİZMETLERİ VE İNŞAAT SAN. TİC. LTD. ŞTİ. · 1 register entry
- RodinacVEM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- Türktipsan Diklofenak SodyumTURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş. · 2 register entries
- VolfenaksMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 4 register entries
- VoltaflamBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- VoltarenGLAXOSMITHKLINE TÜKETİCİ SAĞLIĞI A.Ş., NOVARTİS SAĞLIK GIDA VE TARIM ÜRÜNLERİ SAN. VE TİC. A.Ş. · 9 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
Brand names in 27 more European countries
- Belgium
- Cataflam, Dicloabak, Diclofenac Eg, Diclofenac Eurogenerics, Diclofenac Patch Eg, Diclofenac Retard Eg, Diclofenac Retard Sandoz, Diclofenac Sandoz, Diclotopic, Kinespir Patch, Motifene, Voltaren
- Bulgaria
- Diclofenac-Tchaikapharma, Алмирал, Арестон Инстант, Волтарен, Глимбакс, Диклак, Диклоабак, Диклорапид, Диклофенак Дуо, Диклофлекс, Клодифен, Мобилат, Наклофен, Униклофен, Фелоран
- Croatia
- Diclac Duo, Diclo Duo, Diclorapid, Itami, Klikedi, Lokosol, Naklofen, Varlon, Voltaren
- Cyprus
- Almiral, Areston, Cataflam, Diclac Id, Flamatan, Remethan, Taks, Voltadol, Voltaren
- Czechia
- Almiral, Dicloabak, Diclofenac Al, Diclofenac Dr. Müller Pharma, Diclofenac Duo Pharmaswiss, Diclofenac Galmed, Diclofenac Nutra Essential, Dicoren, Dicuno, Diky, Dolmina, Flexiora, Itami, Olfen, Uno, Veral, Voltaren
- Denmark
- Diclodan, Diclofenac Bluefish, Diclofenac Rapid Teva, Diclon, Dicuno, Diklofenak Orifarm, Solaraze, Spraymik, Voltabak, Voltaren
- Estonia
- Almiral, Dagesil, Diclac, Dicloberl, Diclofenac Ratiopharm, Diclofenac Stada, Dicloflex, Diclomelan Retard, Dicuno, Naklofen, Olfen, Ortofen, Voltaren Akti, Voltaren Aktigo, Voltinex, Volxol
- Finland
- Dicloabak, Diclomex Rapid, Diclospray, Dicuno, Motifene Dual, Solaraze, Voltaren
- France
- Antalcalm, Diclamine, Diclofenac Arrow, Diclofenac Bgr Conseil, Diclofenac Conseil Teva, Diclofenac Delbert, Diclofenac Eg, Diclofenac Lp Biogaran, Diclofenac Lp Venipharm, Diclofenac Lp Viatris, Diclofenac Teva, Diclofenac Urgo, Diclofenac Viatris Sante, Flectortissugelep, Solaraze, Vafotena Lp, Voltarenactigo, Voltarene, Voltarenophta, Voltarenophtabak, Voltarenplast, Voltarenspe
- Greece
- Batafil, Denaclof, Dermoraze, Dicloabak, Dicloral, Dinaclon, Evinopon, Fenaraze, Fenoclof, Flefarmin, Inflaforte, Miniflam, Pain-Out, Pennsaid, Qpain, Remius, Ruvominox, Sailib, Sooneral, Urigon, Voltadol, Voltaren, Voltarol Acti-Go, Vurdon, Zarpen, Ziliprol
- Hungary
- Algoplast, Cataflam, Diclac, Diclofenac Duo Pharmavit, Diclofenac Pp, Diclofenac Ratiopharm, Diclofenac Sandoz, Diclomel Sr, Diflam, Diklofenák-Nátrium Haleon, Dikoral, Doloflex, Fortedol, Voltaren
- Iceland
- Diclofenac Alvogen, Dimax, Modifenac, Solaraze
- Ireland
- Cataflam, Diclac, Diclomel, Difene, Itami, Liderlens, Solaraze, Voltarol
- Italy
- Brexiadvance, Dealgic, Deflamat, Diclocular, Diclofenac Almus, Diclofenac Doc, Diclofenac Eg, Diclofenac Hexal, Diclofenac Mylan, Diclofenac Ratiopharm, Diclofenac Sandoz, Diclofenac Teva, Diclofenac Zentiva, Dicloftil, Diclomed, Dicloreum, Dolaut, Eminocs, Fastuadvance, Fenadol, Fender, Flectorartro, Itami, Itamidol, Itamifast, Levioflex, Leviogel, Lloydol, Muscadvance, Muscoril Dolore E Infiammazione, Pennsaid, Rindox, Solacutan, Solaraze, Traulen, Visunac, Voltadol, Voltadvance, Voltalgan, Voltaren, Voltfast, Zeroflog
- Latvia
- Almiral, Dagesil, Diclac, Dicloberl, Diclofenac Siromed, Diclofenac Stada, Diclofenac Teva, Dicloflex, Diclomelan Retard, Dicuno, Naklofen, Olfen, Ortofēna, Profenac, Uniclophen, Voltaren Akti, Voltaren Aktigo, Voltinex
- Lithuania
- Dagesil, Diclac, Dicloberl, Diclofenac Ratiopharm, Diclofenac Sodium Eletis, Diclofenac Sodium Vudako, Diclofenac Sopharma, Diclofenac Stada, Diclofenac Uno Ratiopharm, Diclomelan Retard, Dicuno, Ditel, Guler, Naklofen, Olfen, Ortofen, Uniclophen, Voltaren Akti, Voltaren Aktigo, Voltinex
- Luxembourg
- Cataflam, Dicloabak, Diclofenac Eg, Diclofenac-Natrium Micro Labs, Diclofenac Patch Eg, Diclofenac Ratiopharm, Diclofenac Retard Eg, Motifene, Solaraze, Voltaren
- Malta
- Almiral, Areston, Catafast, Cataflam, Diclac, Diclomel, Miniflam, Voltaren, Voltarol Muscle & Joint Pain Relief
- Netherlands
- Areston, Dicloabak, Diclofenac Ace, Diclofenac Albert Heijn, Diclofenac Devatis, Diclofenac Etos, Diclofenac Extra Sterk Teva, Diclofenac Htp, Diclofenac Kalium Linn, Diclofenac Kalium Marel, Diclofenac Kalium Spharma, Diclofenac Linn, Diclofenac Mae, Diclofenac Na Cf, Diclofenac Na Zetpil Cf, Diclofenac Potassium Aurobindo, Diclofenac Potassium Marel, Diclofenac Potassium Sameko, Diclofenac Sodium Aurobindo, Diclofenac Trekpleister, Diclofenacnatrium Teva, Eminocs, Kruidvat, Naclof, Trekpleister, Voltaren
- Norway
- Cataflam, Diclofenac Bluefish, Dicuno, Modifenac, Solaraze, Voltaren
- Poland
- Adarostin, Akis, Baxofort, Diclac, Dicloabak, Dicloberl, Dicloduo, Diclofenac, Diclogel, Diclomax, Dicloreum, Diclostim, Diclotica, Dicuno, Diklofenak Perrigo, Diky, Dolomobilat Patch, Felogel Neo, Glimbax, Itami, Majamil, Medulan, Mel Max Actigel, Naclof, Naklofen, Olfen, Solacutan, Voltaren Acti, Voltaren Express, Voltaren Forte, Voltaren Sr
- Portugal
- Dagesil, Dicipan, Diclinov, Dicloabak, Diclodent, Diclofenac Alter, Diclofenac Bluepharma, Diclofenac Farmoz, Diclofenac Generis, Diclofenac Glenmark, Diclofenac Hikma, Diclofenac Labesfal, Diclofenac Medlink, Diclofenac Mylan, Diclofenac Nocegap, Diclofenac Phagecon, Diclofenac Sandoz, Diclofenac Stada, Diclofenac Vitória, Diclogel, Diclokern Spray, Diclospray, Diflac, Dimobil, Dolacen, Dorcalor, Fenil-V, Holactiv, Olfen, Reuloran, Rive, Solaraze, Voltaren, Wergyl, Zaflex
- Romania
- Almiral, Clafen, Diclac, Diclofenac Arena, Diclofenac Chirmis, Diclofenac Dr. Max Pharma S.R.O., Diclofenac Duo Pharmaswiss, Diclofenac Fiterman, Diclofenac Helcor, Diclofenac Mcc, Diclofenac Rompharm, Diclofenac Sc Sintofarm Sa, Diclofenac Sintofarm, Diclofenac Slavia, Diclofenac Sodic Mcc, Diclofenac Stada, Diclofenac Terapia, Diclofenac Tis, Dicloforte, Dicloreum, Diclosal, Diclosin, Diclotard, Diflex, Glimbax, N-Diclofenac, Raplon, Refen, Volini, Voltaren
- Slovakia
- Akis Plus, Almiral, Diclac Retard, Diclobene, Diclofenac Dr. Max, Diclofenac Duo Bausch Health, Diclofenac Pxgpharma, Dicuno, Diky, Glimbax, Itami, Olfen, Uniclophen, Veral, Voltaren
- Slovenia
- Diclo Duo, Dicloflex, Diclojet, Dicuno, Diklofenak Nutra Essential, Itami, Naklofen, Olfen, Voltaren
- Spain
- Cinfadol, Dagesil, Dicloabak, Diclofenaco Abamed, Diclofenaco Alter, Diclofenaco Cinfa, Diclofenaco Lepori, Diclofenaco Llorens, Diclofenaco Normon, Diclofenaco Pensa, Diclofenaco Teva, Diclokern, Dolo-Voltarén, Dolomax, Dolotren, Itami Diario, Olfen, Solacutan, Solaraze, Soliker, Voltadol, Voltarén, Xibol, Zorequin
- Sweden
- Dicloabak, Diclofenac Bluefish, Diclofenac T Ratiopharm, Dicuno, Diklofenak Orifarm, Diklofenak Viatris, Solaraze, Voltaren, Xyd
EMA – Article 57 product data (EU/EEA), 2026-10-28
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Sources
- U.S. Food and Drug Administration. Diclofenac Potassium (AvKARE) – Prescribing Information, 2026-01-13. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=21dc9953-4e6d-50f0-e063-6294a90ac4ef
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.