WHO bleeding scale

Haematology

Also known as: WHO-Blutungsskala · WHO-Blutungsgrade · DSÖ kanama skalası · WHO bleeding scale (grades 0–4)

What it is for

World Health Organization (WHO) scale for the severity of bleeding, mainly used in thrombocytopenia (e.g. chemotherapy-induced, immune thrombocytopenia) and in platelet transfusion research.

Classification

CategoryDescription
Grade 0no bleeding.
Grade 1petechiae (petechial bleeding).
Grade 2mild blood loss (clinically significant).
Grade 3gross blood loss (requiring transfusion).
Grade 4debilitating blood loss (potentially fatal).
Notestudy-specific modified versions define the grades by site, e.g. need for red cell transfusion or haemodynamic compromise; check which version a report uses.

Source

Reporting results of cancer treatment

Cancer 1981;47:207–214 (Miller AB et al.)

DOI: 10.1002/1097-0142(19810101)47:1<207::aid-cncr2820470134>3.0.co;2-6

PMID: 7459811

Edition
WHO toxicity criteria, Miller et al. 1981 (haemorrhage item); many trials use modified, organ-specific versions
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