Binet staging
Haematology
Also known as: Binet-Stadien (CLL) · Binet evrelemesi (KLL) · Binet staging of chronic lymphocytic leukaemia (CLL)
What it is for
Clinical staging of chronic lymphocytic leukaemia by physical examination and blood count. Five areas are counted: (1) head and neck including Waldeyer's ring, (2) axillae, (3) groins including superficial femoral nodes — each counts once even if bilateral — (4) palpable spleen, (5) palpable liver; nodes count when >1 cm.
Classification
| Category | Description |
|---|---|
| Stage A | haemoglobin ≥10 g/dL and platelets ≥100 ×10⁹/L, with fewer than three involved areas. |
| Stage B | haemoglobin ≥10 g/dL and platelets ≥100 ×10⁹/L, with three or more involved areas. |
| Stage C | haemoglobin <10 g/dL and/or platelets <100 ×10⁹/L, regardless of the number of areas. |
Source
A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis
Cancer 1981;48:198–206 (Binet JL et al.)
DOI: 10.1002/1097-0142(19810701)48:1<198::aid-cncr2820480131>3.0.co;2-v
PMID: 7237385
- Edition
- Binet 1981; definitions as in the iwCLL 2018 guidelines
- Checked on
Summary of the published classification in our own words. Not a substitute for the original publication.
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