Rai staging
Haematology
Also known as: modified Rai staging · Rai-Stadien (CLL) · Rai evrelemesi (KLL) · Rai staging of chronic lymphocytic leukaemia (CLL), original and modified
What it is for
Clinical staging of chronic lymphocytic leukaemia by physical examination and blood count; each stage adds a feature to the one before.
Classification
| Category | Description |
|---|---|
| Stage 0 | lymphocytosis in blood and/or marrow only (marrow lymphoid cells >30%). |
| Stage I | lymphocytosis with enlarged lymph nodes. |
| Stage II | lymphocytosis with enlarged spleen and/or liver (nodes enlarged or not). |
| Stage III | lymphocytosis with disease-related anaemia, haemoglobin <11 g/dL. |
| Stage IV | lymphocytosis with disease-related thrombocytopenia, platelets <100 ×10⁹/L. |
| Modified Rai | low risk = stage 0; intermediate risk = stages I–II; high risk = stages III–IV. |
Source
- Edition
- Rai 1975; modified three-group version (low, intermediate, high risk) as in the iwCLL 2018 guidelines
- Checked on
Summary of the published classification in our own words. Not a substitute for the original publication.
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