tadalafil
Adcirca (previously Tadalafil Lilly), Cialis, Tadalafil Lilly · ATC code G04BE08
Brand names: Adcirca, Cialis, Tadalafil Lilly, Lanrektan, Pultadev, Talrektan, Comaxo, Tadagis, Tadahexal, Tadal Pah, Tadamen, Tadipah, Afilta, Dafila, Departon …
- Key facts
- Active substance
- tadalafil
- Drug class
- Drug used in erectile dysfunction
- ATC code
- G04BE08
- Authorisation
- centrally authorised across the EU (EMA)
- Dosage forms
- ADCIRCA 20 mg film-coated tablets · ADCIRCA 2 mg/mL oral suspension · CIALIS 2.5 mg film-coated tablets · CIALIS 5 mg film-coated tablets · CIALIS 10 mg film-coated tablets / CIALIS 20 mg film-coated tablets · Tadalafil Lilly 2.5 mg film-coated tablets · Tadalafil Lilly 5 mg film-coated tablets · Tadalafil Lilly 10 mg film-coated tablets / Tadalafil Lilly 20 mg film-coated tablets
- Marketing authorisation holder
- Eli Lilly Nederland B.V.
- Information as of
- 2026-10-27
Key facts
Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. As Cialis it is used for erectile dysfunction and benign prostatic hyperplasia; as Adcirca for pulmonary arterial hypertension.
What it is used for
- Cialis: erectile dysfunction in adult males (sexual stimulation required); not for women
- Cialis 5 mg: also signs and symptoms of benign prostatic hyperplasia in adult males
- Adcirca: pulmonary arterial hypertension (WHO functional class II and III) in adults and children aged 2 years and above
Dosing
- Cialis, on demand: usually 10 mg before sexual activity, 20 mg if 10 mg is inadequate; at most once per day
- Cialis, once daily for frequent use: 5 mg once daily, possibly 2.5 mg
- Cialis for benign prostatic hyperplasia: 5 mg once daily at about the same time
- Cialis in severe renal impairment: maximum 10 mg; once-a-day dosing not recommended
- Adcirca, adults: 40 mg (two 20 mg tablets) once daily
- Adcirca, children 2 years and above: ≥ 40 kg 40 mg, < 40 kg 20 mg once daily; mild to moderate renal impairment: start at 20 mg
Contraindications
- Hypersensitivity to the active substance or any of the excipients
- Myocardial infarction within the last 90 days, severe hypotension (< 90/50 mm Hg)
- Use of any organic nitrate or guanylate cyclase stimulators such as riociguat
- Loss of vision in one eye due to NAION
Important warnings
- Consider cardiovascular status before treating erectile dysfunction; transient blood pressure decrease
- Priapism: erections lasting 4 hours or more require immediate medical assistance
- Visual defects including NAION, and sudden hearing loss
- Alpha1 blockers: symptomatic hypotension possible; combination with doxazosin not recommended
- Adcirca: not recommended in pulmonary veno-occlusive disease and certain cardiac conditions
Side effects
- Cialis: most common headache, dyspepsia, back pain and myalgia, increasing with dose
- Adcirca (40 mg, ≥ 10%): headache, nausea, back pain, dyspepsia, flushing, myalgia, nasopharyngitis, pain in extremity
- Mostly transient and mild or moderate
Interactions
- Nitrates and riociguat: contraindicated (hypotension)
- Potent CYP3A4 inhibitors (ketoconazole, ritonavir) increase exposure; potent inducers (e.g., rifampicin) decrease it
- Alpha blockers and other antihypertensives: additive blood pressure lowering
Pregnancy and breastfeeding
- Cialis is not indicated for women
- Adcirca: as a precaution, preferably avoided in pregnancy; not used during breast-feeding
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
Common questions – ask Medelix
For patients
Package leaflet, verbatim
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
EU – centrally authorised (all member states)
- Adcirca (previously Tadalafil Lilly)Eli Lilly Nederland B.V. · EMEA/H/C/001021
- CialisEli Lilly Nederland B.V. · EMEA/H/C/000436
- Tadalafil LillyEli Lilly Nederland B.V. · EMEA/H/C/004666
- Tadalafil Mylan · genericMylan Pharmaceuticals Limited · EMEA/H/C/003787
- Talmanco (previously Tadalafil Generics) · genericViatris Limited · EMEA/H/C/004297
Source: European Medicines Agency (EMA), product information
Austria
- LanrektanG.L. Pharma Gmbh · 1 register entry
- PultadevDevatis Gmbh · 1 register entry
- Tadalafil1a Pharma Gmbh, Teva B.V, Genericon Pharma Gesellschaft M.B.H., Holsten Pharma Gmbh, Bluefish Pharmaceuticals Ab, +pharma Arzneimittel Gmbh, Actavis Group Ptc Ehf., Devatis Gmbh, Accord Healthcare B.V., Aristo Pharma Gmbh (Art 57), Sandoz Gmbh, Stada Arzneimittel Gmbh, Krka, D.D., Novo Mesto, Aop Orphan Pharmaceuticals Gmbh · 15 register entries
- TalrektanG.L. Pharma Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- ComaxoHexal Ag · 1 register entry
- PultadevDevatis Gmbh · 1 register entry
- TadagisTad Pharma Gmbh · 1 register entry
- TadahexalHexal Ag · 1 register entry
- Tadal Pah1 A Pharma Gmbh · 1 register entry
- Tadalafil1 A Pharma Gmbh, Day Zero Ehf, Micro Labs Gmbh, Ratiopharm Gmbh, Stadapharm Gmbh, Hec Pharm Gmbh, Puren Pharma Gmbh & Co. Kg, Bluefish Pharmaceuticals Ab, Hormosan Pharma Gmbh, Abdi Farma Gmbh, Betapharm Arzneimittel Gmbh, Abanta Pharma Gmbh, Axcount Generika Gmbh, Devatis Gmbh, Heumann Pharma Gmbh & Co. Generica Kg, Holsten Pharma Gmbh, Zentiva Pharma Gmbh, Accord Healthcare B.V., Amarox Pharma Gmbh, Aristo Pharma Gmbh (Art 57), Basics Gmbh, Hennig Arzneimittel Gmbh & Co. Kg, Aliud Pharma Gmbh, Biomo Pharma Gmbh, Abz-Pharma Gmbh, Axunio Pharma Gmbh · 39 register entries
- TadamenViatris Germany Gmbh · 1 register entry
- TadipahTad Pharma Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- AfiltaSANOFİ İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- CialisLİLLY İLAÇ TİC. LTD. ŞTİ. · 6 register entries
- DafilaWORLD MEDICINE İLAÇLARI LTD. ŞTİ. · 3 register entries
- DepartonABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- DiclasilDR. SERTUS İLAÇ SAN. VE TİC. LTD. ŞTİ. · 8 register entries
- EconixSANOVEL İLAÇ SAN. VE TİC. A.Ş., MONTERO İLAÇ VE GIDA SAN. VE TİC. A.Ş. · 3 register entries
- ErexfilCOSTA SAĞLIK SPOR HİZMETLERİ TİC. LTD. ŞTİ. · 5 register entries
- EronisLİVA İLAÇ PAZARLAMA SAN. VE TİC. A.Ş. · 3 register entries
- FelitasWORLD MEDICINE OPHTHALMICS İLAÇLARI LTD. ŞTİ. · 3 register entries
- FlyntaİLKO İLAÇ SAN.VE TİC. A.Ş. · 5 register entries
- HardcisDEVA HOLDİNG A.Ş. · 5 register entries
- IcarusCENTURİON İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
Show all 34 brand names
- LexNOBEL İLAÇ SAN. VE TİC. A.Ş. · 7 register entries
- LiftaABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 9 register entries
- LongisSANTA FARMA İLAÇ SAN. A.Ş. · 4 register entries
- LongivoORBİS PHARMA İLAÇ VE KİMYA KOZMETİK MEDİKAL SAN. TİC. LTD. ŞTİ. · 6 register entries
- MyesedHUMANİS SAĞLIK A.Ş. · 8 register entries
- NobiciaNOBİS SCİENTİFİC İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- OrcafilWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 8 register entries
- PahtafilSANOFİ İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- PubiltorDEVA HOLDİNG A.Ş. · 1 register entry
- PuldafixFARMA-TEK İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- RekfilBERKO İLAÇ VE KİMYA SAN. A.Ş. · 6 register entries
- TadaciaMİLPHA İLAÇ SANAYİ VE TİCARET LİMİTED ŞİRKETİ · 5 register entries
- TadamedTK İLAÇ MÜMESSİLLİK LTD. ŞTİ. · 6 register entries
- TadarterHUMANİS SAĞLIK A.Ş. · 3 register entries
- TadbeeANDROZY İLAÇ SAĞLIK HİZMETLERİ TİC. LTD. ŞTİ. · 3 register entries
- TadlisNUVOMED İLAÇ SAN.TİC. A.Ş. · 6 register entries
- TadonFARMA-TEK İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- TalafySABA İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
- TalavistPHARMATRUE SAĞLIK MALZEMELERİ A.Ş. · 4 register entries
- TorkBİLİM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- VapoxantWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- VegalisAVRUPA İLAÇ VE KOZMETİK SAN. TİC. A.Ş. · 5 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
Brand names in 28 more European countries
- Belgium
- Quator, Tadalafil Ab, Tadalafil Eg, Tadalafil Eurogenerics, Tadalafil Krka, Tadalafil Sandoz, Tadalafil Teva, Tadalfil Eurogenerics
- Bulgaria
- Героцилан, Гуднес, Егил, Ертос, Зенавил, Касарио, Тадалафи Чайкафарма, Тадалафил Акорд, Тадалафил Актавис, Тадалафил Стада, Тадалафил Чайкафарма, Тадилекто, Тадорекс
- Croatia
- Kasario, Tadalafil Aop, Tadalafil Pliva, Tadilecto, Zenavil
- Cyprus
- Codalis, Genement, Nairem, Tadalafil Accord, Tripan, Zenavil
- Czechia
- Rekifre, Tadalafil Accord, Tadalafil Aop, Tadalafil Aristo, Tadalafil Belupo, Tadalafil Fmk, Tadalafil Medreg, Tadalafil Rontis, Tadalafil Sandoz, Tadalafil Stada, Tadalafil Teva, Tadalafil Zentiva, Tadard, Tadilecto, Zenavil
- Denmark
- Pultadev, Quator, Tadalafil "jubilant", Tadalafil "teva", Tadalafil Accord, Tadalafil Devatis, Tadalafil Farmaprojects, Tadalafil Krka, Tadalafil Orion, Tadalafil Sandoz, Tadalafil Stada
- Estonia
- Quator, Tadalafil Accord, Tadalafil Actavis, Tadalafil Stada, Tadalafil Zentiva, Tadilecto, Zenavil
- Finland
- Pultadev, Tadalafil Accord, Tadalafil Aop, Tadalafil Devatis, Tadalafil Krka, Tadalafil Orion, Tadalafil Ratiopharm, Tadalafil Sandoz, Tadalafil Stada
- France
- Kronalis, Tadalafil Accord, Tadalafil Almus, Tadalafil Arrow, Tadalafil Biogaran, Tadalafil Cristers Pharma, Tadalafil Eg, Tadalafil Evolugen, Tadalafil Krka, Tadalafil La Colina, Tadalafil Quiver, Tadalafil Sandoz, Tadalafil Sun, Tadalafil Teva, Tadalafil Zentiva, Tadalafil Zydus
- Greece
- Adrotan, Diozi, Direxyn, Epulgan, Genement, Lafaval, Ligion, Manifold, Nairem, Newmen®, Ormaz, Quator, Tadalafil Ariti, Tadalafil Flexmed, Tadalafil Heremco, Tadalafil Sandoz, Tadulan, Talys, Zenavil
- Hungary
- Actowill, Bonton, Gerocilan, Rekifre, Tadalafil Accord, Tadalafil Actavis, Tadalafil Aop, Tadalafil Pharmacenter, Tadalafil Rivopharm, Tadalafil Teva, Tadilecto, Tadulan
- Iceland
- Adcirca, Cialis, Halltada, Tadalafil Krka, Tadalafil Lilly, Tadalafil Mylan, Tadalafil Stada, Talmanco
- Ireland
- Cialis For Men, Tadalafil Accord Healthcare Ireland, Tadalafil Brillpharma (Ireland), Tadalafil Clonmel, Tadalafil Krka, Tadalafil Renata Pharmaceuticals (Ireland)
- Italy
- Dalerpen, Dinamis, Dymavig, Sesara, Tadalafil Abc, Tadalafil Abdi, Tadalafil Accord, Tadalafil Almus, Tadalafil Alter, Tadalafil Aristo, Tadalafil Aurobindo, Tadalafil Doc Generici, Tadalafil Eg, Tadalafil Krka, Tadalafil Laboratori Alter, Tadalafil Medreg, Tadalafil Pensa Pharma, Tadalafil Sandoz, Tadalafil Tecnigen, Tadalafil Teva, Tadalafil Zentiva, Tadap, Tadur, Telefil, Teraman, Vicum, Vintox
- Latvia
- Quator, Tadalafil Accord, Tadalafil Aop, Tadalafil Stada, Tadalafil Zentiva, Tadilecto
- Liechtenstein
- Adcirca, Cialis, Tadalafil Lilly, Tadalafil Mylan, Talmanco
- Lithuania
- Quator, Tadalafil Accord, Tadalafil Actavis, Tadalafil Stada, Tadalafil Zentiva, Tadilecto, Zenavil
- Luxembourg
- Tadalafil Eg, Tadalafil Eurogenerics, Tadalafil Micro Labs, Tadalafil Pah Micro Labs
- Malta
- Avarante, Goyuma, Tadagis, Tadalafil Aristo, Tadalafil Clonmel, Tadalafil Maxmind, Tadalafil Rontis, Tripan, Zenavil
- Netherlands
- Gerocilan, Lafaval, Ligion, Pultadev, Qizerz, Quator, Tadalafi Sandoz, Tadalafil, Tadulan, Teldana, Yanatawa, Zenavil
- Norway
- Adcirca, Avarante, Cialis, Pultadev, Tadalafil Accord, Tadalafil Bluefish, Tadalafil Cipla, Tadalafil Devatis, Tadalafil Krka, Tadalafil Lilly, Tadalafil Mylan, Tadalafil Orion, Tadalafil Sandoz, Tadalafil Stada, Tadalafil Teva, Talmanco
- Poland
- Adalift, Akyris, Erlis, Gerocilan, Menero, Profitadal, Rekifre, Tadacontrol, Tadalafil Apteo Med, Tadalafil Aristo, Tadalafil Aurovitas, Tadalafil Belupo, Tadalafil Egis, Tadalafil Fortis, Tadalafil Inventum, Tadalafil Maxigra Zakłady Farmaceutyczne Polpharma, Tadalafil Maxon, Tadalafil Medreg, Tadalafil Mensil, Tadalafil Polpharma, Tadalafil Sandoz, Tadalafil Stada, Tadalafil Sun, Tadalafil Teva, Tadalafil Zentiva, Tadaxin, Tadilecto
- Portugal
- Direxyn, Filaz, Genement, Nairem, Quator, Tadalafil Alter, Tadalafil Aristo, Tadalafil Aurovitas, Tadalafil Azevedos, Tadalafil Biofarmoz, Tadalafil Bluepharma, Tadalafil Ciclum, Tadalafil Farmoz, Tadalafil Generis, Tadalafil Jaba, Tadalafil Koanaa, Tadalafil Krka, Tadalafil Pentafarma, Tadalafil Pharmakern, Tadalafil Ratiopharm, Tadalafil Reconir, Tadalafil Sandoz, Tadalafil Stada, Tadalafil Tecnigen, Tadalafil Teva, Tadalafil Tolife, Tadalafil Venxal, Tadalafil Vitória, Tadalafil Zentiva, Tadamen, Talys, Vantadaful, Zarvite, Zenavil
- Romania
- Arvalti, Gerocilan, Tadalafil Accord, Tadalafil Gemax Pharma, Tadilecto, Tadulan, Xeneso
- Slovakia
- Gerocilan, Tadalafil Accord, Tadalafil Aop, Tadalafil Belupo, Tadalafil Fmk, Tadalafil Medreg, Tadalafil Teva, Tadard, Tadilecto, Tadulan, Talaft, Zenavil
- Slovenia
- Kasario, Quator, Tadagis, Tadalafil Belupo, Tadalafil Krka, Tadalafil Lek, Tadilecto, Tadipah
- Spain
- Acore, Alneo, Arvalti, Citax, Filtax, Qizerz, Tadalafil Qilu, Tadalafil Stada, Tadalafil Tadalafilo Jubilant, Tadalafilo Abdi, Tadalafilo Accord, Tadalafilo Almus, Tadalafilo Alter, Tadalafilo Aristo, Tadalafilo Aurovit, Tadalafilo Aurovitas, Tadalafilo Cinfa, Tadalafilo Cipla, Tadalafilo Combix, Tadalafilo Farmalter, Tadalafilo Kern Pharma, Tadalafilo Krka, Tadalafilo Mabo, Tadalafilo Normogen, Tadalafilo Normon, Tadalafilo Pensa, Tadalafilo Qualigen, Tadalafilo Sandoz, Tadalafilo Stada, Tadalafilo Stadagen, Tadalafilo Tarbis, Tadalafilo Tecnimede, Tadalafilo Teva-Ratiopharm, Tadalafilo Viatris Pharmaceuticals, Tadalafilo Zentiva, Victogón, Virvirilo
- Sweden
- Pultadev, Tadalafil, Vixantus, Yanatawa
EMA – Article 57 product data (EU/EEA), 2026-10-28
Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.
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Sources
- European Medicines Agency. Adcirca (previously Tadalafil Lilly) – EPAR, Product Information (OF THE TEXT Detailed information on this medicinal product i). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/adcirca-epar-product-information_en.pdf
- European Medicines Agency. Cialis – EPAR, Product Information (OF THE TEXT Detailed information on this medicinal product i). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/cialis-epar-product-information_en.pdf
- European Medicines Agency. Tadalafil Lilly – EPAR, Product Information (OF THE TEXT Detailed information on this medicinal product i). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/tadalafil-lilly-epar-product-information_en.pdf
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
- Wikidata (CC0): ATC G04BE.
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: European Medicines Agency (EMA), product information. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.