Piroxicam
Felden Quick-Solve · ATC code M02AA07
Also known as: Piroksikam · Brand names: Felden Quick-Solve, Piroxicam Abz, Piroxicam Hexal, Piroxicam Ratiopharm, Aljeks, Locojel, Paxambio, Piroxyn, Rawex, Tencas, Terapix %
- Key facts
- Active substance
- Piroxicam
- ATC code
- M02AA07
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-29
Boxed warning
Cardiovascular Thrombotic Events
- Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use [see Warnings and Precautions (5.1)].
- Piroxicam capsules are contraindicated in the setting of coronary artery bypass graft (CABG) surgery [see Contraindications (4) and Warnings and Precautions (5.1)].
Gastrointestinal Bleeding, Ulceration, and Perforation
- NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events [see Warnings and Precautions (5.2)].
Key facts
Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) with a long half-life. Per the US prescribing information, it is used to relieve the signs and symptoms of osteoarthritis and rheumatoid arthritis.
What it is used for
- Relief of the signs and symptoms of osteoarthritis
- Relief of the signs and symptoms of rheumatoid arthritis
Dosing
- Use the lowest effective dosage for the shortest duration
- 20 mg orally once per day; the daily dose may be divided if desired
- Because of the long half-life, steady state is not reached for 7 to 12 days; do not assess the effect for two weeks
- Adjust dose and frequency to the individual response
Contraindications
- Known hypersensitivity (e.g. anaphylactic reactions, serious skin reactions) to piroxicam or any component
- History of asthma, urticaria or other allergic-type reactions after aspirin or other NSAIDs
- Setting of CABG surgery
Important warnings
- Boxed warning: increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal and may occur early in treatment
- Boxed warning: serious GI bleeding, ulceration and perforation, at any time and without warning; elderly patients and those with prior ulcer or bleeding at greater risk
- Hepatotoxicity, hypertension, heart failure and edema
- Renal toxicity and hyperkalemia
- Anaphylactic reactions and serious skin reactions; hematologic toxicity
Side effects
- In approximately 1% to 10%: edema, anorexia, abdominal pain, constipation, diarrhea, flatulence, nausea, vomiting
- Dizziness, headache, vertigo, pruritus, rash, tinnitus
- Occasionally palpitations, stomatitis
Interactions
- Anticoagulants (e.g. warfarin), antiplatelet drugs (e.g. aspirin), SSRIs and SNRIs: increased bleeding risk; monitor for bleeding
- Further interactions (including aspirin, antihypertensives): see the full prescribing information
Pregnancy and breastfeeding
- Limit dose and duration between about 20 and 30 weeks of gestation; avoid from about 30 weeks
- Risk of premature closure of the ductus arteriosus and fetal renal dysfunction with oligohydramnios
Summary of the official product information, written with AI on 2026-10-29. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
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For patients
Patient information (US)
This product has no separate US patient information.
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- Felden Quick-SolvePfizer Corporation Austria Ges.M.B.H. · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29
Germany
- Piroxicam AbzAbz-Pharma Gmbh · 1 register entry
- Piroxicam HexalHexal Ag · 1 register entry
- Piroxicam RatiopharmRatiopharm Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29
Turkey
- AljeksMEGA FARMA İLAÇ VE KOZMETİK SAN. TİC. PAZ. LTD. ŞTİ. · 1 register entry
- LocojelİNTRALİNE İLAÇ SAĞLIK HİZMETLERİ İTHALAT İHRACAT SAN. VE TİC. A.Ş. · 1 register entry
- PaxambioGENBİO İLAÇ SAN. VE TİC. LTD. ŞTİ. · 1 register entry
- PiroxynHAKAY İLAÇ PAZARLAMA SAN. VE TİC. LTD. ŞTİ. · 1 register entry
- RawexFORTEMPHARMA İLAÇ SAN. VE TİC. LTD. ŞTİ. · 1 register entry
- TencasRİBO GEN İLAÇ SAĞLIK HİZMETLERİ İTHALAT İHRACAT SANAYİ TİCARET A.Ş. · 1 register entry
- Terapix %ABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
Brand names in 14 more European countries
- Belgium
- Piroxicam Eg, Piroxicam Sandoz
- Bulgaria
- Пироксикам Екофарм, Пироксикам Софарма
- Croatia
- Lubor, Luboreta
- Cyprus
- Feldene, Roxitan, Sotilen
- Finland
- Piroxin
- France
- Feldene, Piroxicam Biogaran, Piroxicam Dispersible Pfizer, Piroxicam Eg, Piroxicam Teva, Piroxicam Viatris, Zofora
- Greece
- Feldene, Proponol, Zerospasm
- Italy
- Brexidol Unidie, Dolaut Mono, Feldene, Flector Unidie, Ilmodol Dolore E Infiammazione, Ipsoflog, Lenospread, Lenotac, Pirobec, Piroftal, Piroxicam Doc, Piroxicam Eg, Reumagil
- Luxembourg
- Piroxicam Eg
- Norway
- Piroxicam Viatris
- Poland
- Piroxicam Jelfa
- Portugal
- Flexar, Piroxicam Pensavital, Piroxicam Ratiopharm, Remisil, Reumoxican
- Romania
- Piroxicam, Piroxsal
- Spain
- Piroxicam Cinfa, Salvacam
EMA – Article 57 product data (EU/EEA), 2026-10-29
Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.
Another question about this substance?
Medelix answers clinical questions from guidelines, studies and product information – every claim with its source.
Sources
- U.S. Food and Drug Administration. Piroxicam (Teva Pharmaceuticals USA, Inc.) – Prescribing Information, 2026-08-19. DailyMed (NLM), 2026-10-29. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f1123fe1-b79c-430b-8548-08cd6e518482
- EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
Editorial: Medelix editorial team · last updated 2026-10-29 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.