Pantoprazole

Gastroloc, Gastrozol, Nolpaza Control, Panprabene · ATC code A02BC02

Also known as: Pantoprazol · Brand names: Gastroloc, Gastrozol, Nolpaza Control, Panprabene, Pantip, Pantoloc, Refluxin, Zurcal, Panto, Pantomol, Pantozol, Rifun, Zurcal S, Abpax, Arinna …

Key facts
Active substance: Pantoprazole
ATC code: A02BC02
Authorisation: authorised nationally; no central EU authorisation
Information as of: 2026-10-27

Key facts

Pantoprazole is a proton pump inhibitor (PPI). Per the US prescribing information (delayed-release tablets), it treats erosive esophagitis from GERD and pathological hypersecretory conditions.

What it is used for

Short-term treatment of erosive esophagitis with GERD (adults and children five years and older)
Maintenance of healing of erosive esophagitis in adults
Pathological hypersecretory conditions including Zollinger-Ellison syndrome

Dosing

Erosive esophagitis, adults: 40 mg once daily for up to 8 weeks; an additional 8-week course may be considered if not healed.
Children 5 years and older: ≥15 kg to <40 kg 20 mg, ≥40 kg 40 mg once daily for up to 8 weeks.
Maintenance, adults: 40 mg once daily.
Zollinger-Ellison syndrome: 40 mg twice daily, adjusted individually; doses up to 240 mg daily have been given.
Swallow tablets whole; do not split, chew or crush; with or without food.

Contraindications

Hypersensitivity to any component or substituted benzimidazoles
Concomitant rilpivirine-containing products

Important warnings

Symptomatic response does not preclude gastric malignancy
Acute tubulointerstitial nephritis
Clostridium difficile-associated diarrhea; use the lowest dose and shortest duration
Bone fracture, severe cutaneous reactions, cutaneous and systemic lupus
Vitamin B-12 deficiency, hypomagnesemia, fundic gland polyps

Side effects

Headache (12.2%), diarrhea (8.8%), nausea (7%), abdominal pain (6.2%)
Vomiting (4.3%), flatulence (3.9%), dizziness (3%), arthralgia (2.8%)
Serious: tubulointerstitial nephritis, C. difficile diarrhea, fractures, severe skin reactions

Interactions

Rilpivirine: contraindicated; avoid nelfinavir; atazanavir and saquinavir per their labeling
Warfarin: monitor INR and prothrombin time
Methotrexate (mainly high dose): methotrexate levels may rise
Clopidogrel: no dose adjustment needed

Pregnancy and breastfeeding

Observational studies did not show an association with major malformations or other adverse pregnancy outcomes.

Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

Common questions – ask Medelix

For patients

Patient information (US)

Patient information (US) →

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

Austria

GastrolocHexal Pharma Gmbh · 1 register entry
GastrozolDermapharm Gmbh · 1 register entry
Nolpaza ControlKrka, D.D., Novo Mesto · 1 register entry
PanprabeneTeva B.V · 1 register entry
PantipG.L. Pharma Gmbh · 2 register entries
PantolocTakeda Pharma Ges.M.B.H. · 2 register entries
Pantoprazol1a Pharma Gmbh, Towa Pharmaceutical Europe S.L., Teva B.V, Apta Medica Internacional D.O.O., Krka, D.D., Novo Mesto, Genericon Pharma Gesellschaft M.B.H., Actavis Group Ptc Ehf., Bluefish Pharmaceuticals Ab, +pharma Arzneimittel Gmbh, Gen Ilac Germany Gmbh, Kalceks, Noridem Enterprises Ltd, Takeda Gmbh, G.L. Pharma Gmbh, Sandoz Gmbh, A-Med Gmbh, Hikma Farmacêutica (Portugal), S.A., Stada Arzneimittel Gmbh, Sun Pharmaceutical Industries Europe B.V. · 26 register entries
RefluxinStada Arzneimittel Gmbh · 1 register entry
ZurcalTakeda Austria Gmbh · 2 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Germany

PantoMicro Labs Gmbh, Aristo Pharma Gmbh (Art 57) · 2 register entries
PantomolRatiopharm Gmbh · 1 register entry
PantoprazolTillomed Pharma Gmbh, 1 A Pharma Gmbh, Heumann Pharma Gmbh & Co. Generica Kg, Axicorp Pharma Gmbh, Hennig Arzneimittel Gmbh & Co. Kg, Tad Pharma Gmbh, Aliud Pharma Gmbh, Dexcel Pharma Gmbh, Puren Pharma Gmbh & Co. Kg, Stada Consumer Health Deutschland Gmbh, Ratiopharm Gmbh, Ever Valinject Gmbh, Micro Labs Gmbh, Lannacher Heilmittel Ges.M.B.H.,, Fairmed Healthcare Gmbh, Macleods Pharma España, S.L.U, Winthrop Arzneimittel Gmbh, Gen Ilac Germany Gmbh, Kalceks, Noridem Enterprises Ltd, Amarox Pharma Gmbh, Ametas Medical Gmbh, Aristo Pharma Gmbh (Art 57), Axunio Pharma Gmbh, Basics Gmbh, Laboratorios Normon, S.A., Biomo Pharma Gmbh, Hexal Ag, Hikma Farmacêutica (Portugal), S.A., Eugia Pharma (Malta) Limited, Stadapharm Gmbh, Stada Arzneimittel Ag, Zentiva Pharma Gmbh, Betapharm Arzneimittel Gmbh, Denk Pharma Gmbh & Co. Kg, Viatris Germany Gmbh, Mibe Gmbh Arzneimittel, Juta Pharma Gmbh, Aaa-Pharma Gmbh, Abz-Pharma Gmbh, Takeda Gmbh, Sun Pharmaceuticals Germany Gmbh · 60 register entries
PantozolTakeda Gmbh · 2 register entries
RifunTakeda Gmbh · 1 register entry
Zurcal STakeda Gmbh · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Turkey

AbpaxNOBEL SAĞLIK ÜRÜNLERİ LTD ŞTİ · 2 register entries
ArinnaTERRA İLAÇ VE KİMYA SAN. TİC. A.Ş. · 2 register entries
GaspazolDEM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
GastblokUMUT İLAÇ TİC. VE SAN. LTD. ŞTİ. · 2 register entries
Gastrazol-LGENSENTA İLAÇ SANAYİ VE TİC. A.Ş. · 1 register entry
HelicrazolAROMA İLAÇ SAN. LTD. ŞTİ. · 1 register entry
JectopanTÜM-EKİP İLAÇ A.Ş. · 1 register entry
PandevDEVA HOLDİNG A.Ş. · 5 register entries
PanocerİLKO İLAÇ SAN.VE TİC. A.Ş. · 2 register entries
PanrefBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
PantactiveHUMANİS SAĞLIK A.Ş. · 4 register entries
PantgesPHARMATRUE SAĞLIK MALZEMELERİ A.Ş. · 2 register entries

Show all 33 brand names

PanthecSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
PantoSANDOZ İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
PantonixKOÇ İLAÇ SANAYİ VE TİC. A.Ş. · 1 register entry
PantozolINCPHARMA İLAÇ SAN. VE TİC. LTD. ŞTİ. · 2 register entries
PantpasACİNO TURKEY İLAÇ A.Ş. · 4 register entries
PasmolHAVER TRAKYA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
PenzolPENSA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
PlapantWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
ProgasVEM İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
ProtazHTA İLAÇ ARAŞTIRMA GELİŞTİRME SAN.VE TİC. LTD. ŞTİ. · 1 register entry
ProtechDROGSAN İLAÇLARI SAN. VE TİC. A.Ş. · 4 register entries
ProtinumALİ RAİF İLAÇ SAN. A.Ş. · 5 register entries
ProtonexABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 6 register entries
PulcetNOBEL İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
SormitorWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
StamicHELBA İLAÇ İÇ VE DIŞ SAN. TİC. A.Ş. · 2 register entries
UlcezolKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 1 register entry
UlcoreksBİLİM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
UlsepanWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
ZolcerCENTURİON İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
ZygosisPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

USA

Protonix Delayed-ReleaseWyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. · 1 register entry
Protonix I.V.Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. · 3 register entries

Source: U.S. FDA – Drug labels (openFDA/DailyMed), as of 2026-10-28

Brand names in 28 more European countries

Belgium: Ippracid, Maalox Control, Pantogastrix, Pantomed, Pantoprazol Ab, Pantoprazol Eugia, Pantoprazol Hikma, Pantoprazol Krka, Pantoprazol Sandoz, Pantoprazol Sun, Pantoprazole Accord Healthcare, Pantoprazole Eg, Pantoprazole Kalceks, Pantoprazole Teva, Pantoprazole Viatris, Pantozol
Bulgaria: Pantoprazole Tchaikapharma, Контролок, Ноацид, Нолпаза, Панразол, Пантопразол Акорд, Пантопразол Алуфарма, Пантопразол Аптафарма, Пантопразол Зентива, Пантопразол Кrka, Пантопразол Калцекс, Пантопразол Полфарма, Пантопразол Ромфарм, Пантопразол Стада, Пантул, Празолид, Пулсет, Улсепан, Хеликс
Croatia: Acipan, Apazol A, Controloc, Nolpaza, Pantoprazol Alkaloid, Pantoprazol Apharma, Pantoprazol Aptapharma, Pantoprazol Devatis, Pantoprazol Kalceks, Pantoprazol Pharmas, Pantoprazol Sandoz, Zipantola, Zoltex, Zoprax
Cyprus: Berozol, Contro- Cap, Controloc, Erozol, Pantarol, Pantoflux, Pantoprazole Accord, Pantoprazole Aptapharma, Pantoprazole Aurobindo, Pantoprazole Delorbis, Pantoprazole Noridem, Pantoprazole Normon, Pantoprazole Tad, Reprat
Czechia: Controloc, Nolpaza, Pantomyl, Pantoprazol +pharma, Pantoprazol Agmed, Pantoprazol Kalceks, Pantoprazol Krka, Pantoprazol Noridem, Pantoprazol Olikla, Pantoprazol Sanexcel, Pantoprazole Aptapharma, Pantoprazole Olikla, Pantoprazole Polpharma, Pantoprazole Zentiva
Denmark: Pantoloc, Pantoprazol "sandoz", Pantoprazol Accord, Pantoprazol Genilac Germany Gmbh, Pantoprazol Kalceks, Pantoprazol Krka, Pantoprazol Opko Health Spain, Pantoprazol Orion, Pantoprazol Pakningsstørrelser >, Pantoprazol Pensa, Pantoprazol Reig Jofre, Pantoprazol Stada, Pantoprazol Sun, Pantoprazol Takeda, Pantoprazol Viatris, Pantoprazole Noridem, Pantoprazole Pakningsstørrelser =, Pantoprazole Pakningsstørrelser >, Pantoprazole Stada, Pantoprazole Teva
Estonia: Controloc, Ipraalox, Nolpaza, Pantoprazol Ratiopharm, Pantoprazole Actavis, Pantoprazole Inpharmatis, Pantoprazole Mepha, Pantoprazole Norameda, Panzilan
Finland: Pantopratsoli Sun, Pantoprazol Accord, Pantoprazol Actavis, Pantoprazol Krka, Pantoprazol Orion, Pantoprazol Sun, Pantoprazol Viatris, Pantoprazole Kalceks, Pantoprazole Norameda, Pantoprazole Noridem, Pantoprazole Ratiopharm, Pantoprazole Stada, Somac
France: Eupantol, Inipomp, Ipraalox, Pantoprazole Almus, Pantoprazole Arrow, Pantoprazole Biogaran, Pantoprazole Cristers, Pantoprazole Eg, Pantoprazole Evolugen, Pantoprazole Hikma, Pantoprazole Kalceks, Pantoprazole Krka, Pantoprazole Noridem, Pantoprazole Reig Jofre, Pantoprazole Sandoz, Pantoprazole Sun, Pantoprazole Teva Sante, Pantoprazole Teva Teva Conseil, Pantoprazole Tillomed, Pantoprazole Viatris, Pantoprazole Zentiva, Pantoprazole Zf, Pantoprazole Zydus
Greece: Acidwell, Controloc, Gastrol, Ozepran, Pantarol, Pantium, Pantoprazole I.V. Biomedic Laboratories, Pantoprazole Kleva, Pantoprazole Tad, Pantoprazole Verisfield, Pantoprol, Pantosec, Pantozol, Portorin, Praz- Up, Pronzek, Ulceron, Zurcazol
Hungary: Acida, Controloc, Gaxtron Start, Noacid, Nolpaza, Pantacid Flux, Pantoprazol, Pantoprazole Apharma, Pantoprazole Stada, Pantoprazole Teva, Ulprix
Iceland: Controloc Control, Pantoprazole Stada, Pantozol Control, Somac Control
Ireland: Nolpacid, Nolpaza, Pantium, Pantoprazole As Kalceks, Pantoprazole Azevedos, Pantoprazole Bluefish, Pantoprazole Laboratorio Reig Jofre, Pantoprazole Noridem, Pantoprazole Teva Pharma, Pantup, Protium, Protizole
Italy: Eugastrol Reflusso, Gastroloc, Inipant, Inizol, Maalox Reflusso, Nolpaza, Pancleus, Pantecta, Pantofir, Pantopan, Pantoprazole Sodium Sun, Pantoprazole Sodium Teva Italia, Pantoprazole Teva Italia, Pantoprazolo Abc, Pantoprazolo Accord Healthcare, Pantoprazolo Almus, Pantoprazolo Alter, Pantoprazolo Aristo Pharma, Pantoprazolo Aurobindo, Pantoprazolo Doc, Pantoprazolo Eg, Pantoprazolo Git, Pantoprazolo Hikma, Pantoprazolo Krka, Pantoprazolo Mylan, Pantoprazolo Noridem, Pantoprazolo Pensa, Pantoprazolo Sandoz, Pantoprazolo Sun, Pantoprazolo Tecnigen Italia, Pantoprazolo Teva, Pantoprazolo Tillomed, Pantoprazolo Towa, Pantoprazolo Zentiva, Pantorc, Pantorex, Peptazol, Prinzol, Sedipanto, Stomadol Reflusso, Xoolam Reflusso, Zolemer Reflusso, Zolium, Zolonib
Latvia: Controloc, Nolpaza, Pantoprazole Actavis, Pantoprazole Kalceks, Pantoprazole Mepha, Pantoprazole Norameda, Pantoprazole Unifarma, Panzilan
Liechtenstein: Controloc Control, Pantozol Control, Somac Control
Lithuania: Controloc, Nolpaza, Pantoprazole Actavis, Pantoprazole Ibe, Pantoprazole Ingen Pharma, Pantoprazole Kalceks, Pantoprazole Norameda, Panzilan
Luxembourg: Pantomed, Pantoprazol Ratiopharm, Pantoprazol Sandoz, Pantoprazole Eg, Pantoprazole Viatris, Pantozol
Malta: Panto Tad, Pantoprazole Aptapharma, Pantoprazole Aurobindo Pharma (Malta), Pantoprazole Azevedos
Netherlands: Ipraalox, Maagzuurremmende, Maagzuurtabletten Pantoprazol Healthypharm, Maagzuurtabletten Pantoprazol Htp, Maagzuurtabletten Pantoprazol Sam, Pantogerolan, Pantoprazol, Pantoprazole Sodium Sesquihydrate Aurobindo, Pantoprazole Sodium Sesquihydrate Eugia, Pantozol, Previfect
Norway: Controloc Control, Pantoprazol Actavis, Pantoprazol Kalceks, Pantoprazol Krka, Pantoprazol Pensa, Pantoprazol Sun, Pantoprazole Gen, Pantoprazole Noridem, Pantoprazole Stada, Pantozol Control, Somac
Poland: Anesteloc, Contix, Controloc, Gerdin, Ipp, Noacid, Nolpaza, Ozzion, Pamyl, Panprazox, Panrazol, Pantopraz, Pantoprazol Accord, Pantoprazol Aurovitas, Pantoprazol Krka, Pantoprazol Noridem, Pantoprazol Pharmline, Pantoprazol Sanexcel, Pantoprazol Sun, Pantoprazol Teva, Pantoprazol Towa Pharmaceutical Europe, Pantoprazol Zentiva, Pantoprazole, Pantosis Max, Panzol, Polpanto, Ranloc
Portugal: Apton, Kairol, Pantoc, Pantoprazol Accord, Pantoprazol Altan, Pantoprazol Alter, Pantoprazol Aristo, Pantoprazol Aurobindo, Pantoprazol Aurovitas, Pantoprazol Azevedos, Pantoprazol Basi, Pantoprazol Biofarmoz, Pantoprazol Bluefish, Pantoprazol Bluepharma, Pantoprazol Braiter, Pantoprazol Ciclum, Pantoprazol Digespan, Pantoprazol Farmoz, Pantoprazol Generis, Pantoprazol Hikma, Pantoprazol I.V. Basi, Pantoprazol I.V. Reig Jofre, Pantoprazol Isab, Pantoprazol Kalceks, Pantoprazol Krka, Pantoprazol Lumec, Pantoprazol Medlink, Pantoprazol Mepha, Pantoprazol Mylan, Pantoprazol Neutraz, Pantoprazol Noridem, Pantoprazol Normon, Pantoprazol Omnicals, Pantoprazol Pentafarma Genéricos, Pantoprazol Pharmacare, Pantoprazol Pharmakern, Pantoprazol Ratiopharm, Pantoprazol Reiwa Healthcare, Pantoprazol Sandoz, Pantoprazol Tecnigen, Pantoprazol Tecnilor, Pantoprazol Tetrafarma, Pantoprazol Teva, Pantoprazol Tolife, Pantoprazol Zentiva, Pantoxobe, Zipantol, Zurcal
Romania: Controloc, Nedis, Nolpaza, Pacid, Pantoprazol Aptapharma, Pantoprazol Atb, Pantoprazol Gemax, Pantoprazol Kalceks, Pantoprazol Noridem, Pantoprazol Rompharm, Pantoprazol Sanexcel, Pantoprazol Sun, Pantoprazol Terapia, Seltraz, Zencopan
Slovakia: Controloc, Nolpaza, Ozzion, Pantomyl, Pantoprazol Accord, Pantoprazol Kalceks, Pantoprazol Krka, Pantoprazol Noridem, Pantoprazol Sandoz, Pantoprazol Stada, Pantoprazole Aptapharma, Pantoprazole Olikla, Pantoprazole Polpharma
Slovenia: Acipan, Controloc, Nolpaza, Pantoprazol Accord, Pantoprazol Apharma, Pantoprazol Apta, Pantoprazol Aptapharma, Pantoprazol Kalceks, Pantoprazol Teva
Spain: Alapanzol, Anagastra, Citrel, Codramol, Nolpaza, Normogastrol, Pantecta, Pantoprazol Almus, Pantoprazol Altan, Pantoprazol Alter, Pantoprazol Aristo, Pantoprazol Aurovitas, Pantoprazol Bluefish, Pantoprazol Cinfa, Pantoprazol Davur, Pantoprazol Durban, Pantoprazol Farmalider, Pantoprazol Geiser, Pantoprazol Gobens, Pantoprazol Hikma, Pantoprazol Kalceks, Pantoprazol Kern Pharma, Pantoprazol Krka, Pantoprazol Mabo, Pantoprazol Normogen, Pantoprazol Normon, Pantoprazol Opko, Pantoprazol Pensa, Pantoprazol Pharma Combix, Pantoprazol Qualigen, Pantoprazol Recordati, Pantoprazol Reiwa Healthcare, Pantoprazol Sandoz, Pantoprazol Serraclinics, Pantoprazol Stada, Pantoprazol Sun, Pantoprazol Tarbis, Pantoprazol Tecnigen, Pantoprazol Teva-Ratio, Pantoprazol Viatris, Pantoprazol Vir Pharma, Pensavital
Sweden: Pantoloc, Pantoprazol Accord, Pantoprazol Actavis, Pantoprazol Amarox, Pantoprazol Krka, Pantoprazol Orion, Pantoprazol Sandoz, Pantoprazol Sun, Pantoprazol Viatris, Pantoprazole Genilac, Pantoprazole Kalceks, Pantoprazole Noridem, Pantoprazole Stada Stada, Pantoprazole Teva

EMA – Article 57 product data (EU/EEA), 2026-10-28

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Sources

U.S. Food and Drug Administration. pantoprazole sodium (Granules Pharmaceuticals Inc.) – Prescribing Information, 2026-04-06. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=8f2fb647-15bc-41cb-84a4-02e956e614fc
EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
U.S. FDA – Drug labels (openFDA/DailyMed), 2026-10-28. https://dailymed.nlm.nih.gov/dailymed/

Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error

Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.