Ondansetron
Ondansan, Ondansetron Accord, Ondansetron B. Braun, Ondansetron Bluefish · ATC code A04AA01
Brand names: Ondansan, Ondansetron Accord, Ondansetron B. Braun, Ondansetron Bluefish, Ondansetron Carinopharm, Ondansetron Hikma, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Noridem, Ondansetron Sandoz, Ondansetron Tenshi Kaizen, Zofran, Zofran®, Cellondan, Onsetron …
- Key facts
- Active substance
- Ondansetron
- ATC code
- A04AA01
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-27
Key facts
Ondansetron is a selective 5-HT3 receptor antagonist (antiemetic). Per the US label it is used to prevent nausea and vomiting with chemotherapy, radiotherapy and after surgery.
What it is used for
- Prevention of nausea and vomiting with highly emetogenic chemotherapy, including cisplatin ≥ 50 mg/m²
- Initial and repeat courses of moderately emetogenic chemotherapy
- Radiotherapy (total body irradiation or abdominal radiotherapy)
- Postoperative nausea and/or vomiting
Dosing
- Highly emetogenic chemotherapy (adults): single 24 mg dose 30 minutes before
- Moderately emetogenic chemotherapy (adults and 12 to 17 years): 8 mg 30 minutes before, 8 mg 8 hours later, then 8 mg every 12 hours for 1 to 2 days
- Total body irradiation: 8 mg 1 to 2 hours before each fraction
- Postoperative: 16 mg 1 hour before induction of anaesthesia
- Severe hepatic impairment (Child-Pugh 10 or greater): do not exceed 8 mg per day; further paediatric dosing in the full text
Contraindications
- Hypersensitivity (e.g. anaphylaxis) to ondansetron or any component
- Concomitant apomorphine (profound hypotension and loss of consciousness)
Important warnings
- Hypersensitivity reactions including anaphylaxis and bronchospasm
- QT prolongation and Torsade de Pointes; avoid in congenital long QT syndrome, ECG monitoring with risk factors
- Serotonin syndrome, particularly with other serotonergic drugs
- Myocardial ischaemia; masking of progressive ileus
Side effects
- Common: headache and diarrhoea, also constipation and fatigue
- Serious: hypersensitivity reactions, QT prolongation, serotonin syndrome, myocardial ischaemia
Interactions
- Serotonergic drugs (SSRIs, SNRIs): risk of serotonin syndrome
- Apomorphine: contraindicated
- QT-prolonging medicines: ECG monitoring; CYP enzyme effects in the full text
Pregnancy and breastfeeding
- Studies on birth defects are inconsistent and do not allow conclusions about safety
- Present at low levels in human milk; clinically relevant infant exposure unlikely
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
Common questions – ask Medelix
For patients
Patient information (US)
This product has no separate US patient information.
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- OndansanG.L. Pharma Gmbh · 3 register entries
- Ondansetron AccordAccord Healthcare B.V. · 1 register entry
- Ondansetron B. BraunB.Braun Melsungen Ag · 1 register entry
- Ondansetron BluefishBluefish Pharmaceuticals Ab · 1 register entry
- Ondansetron CarinopharmCarinopharm Gmbh · 1 register entry
- Ondansetron HikmaHikma Farmacêutica (Portugal), S.A. · 1 register entry
- Ondansetron KabiFresenius Kabi Austria Gmbh · 1 register entry
- Ondansetron KalceksKalceks · 1 register entry
- Ondansetron NoridemNoridem Enterprises Ltd · 1 register entry
- Ondansetron SandozSandoz Gmbh · 1 register entry
- Ondansetron Tenshi KaizenInstapill B.V. · 1 register entry
- ZofranSandoz Gmbh · 1 register entry
Show all 13 brand names
- Zofran®Sandoz Gmbh · 2 register entries
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- CellondanStadapharm Gmbh · 3 register entries
- Ondansetron1 A Pharma Gmbh, Instapill B.V., Carinopharm Gmbh, Ever Valinject Gmbh, Ratiopharm Gmbh, Teva Gmbh, Eugia Pharma (Malta) Limited, Puren Pharma Gmbh & Co. Kg, B.Braun Melsungen Ag, Bluefish Pharmaceuticals Ab, Tillomed Pharma Gmbh, Kalceks, Noridem Enterprises Ltd, Troikaa Pharmaceuticals Europe S.R.O., Accord Healthcare B.V., Aristo Pharma Gmbh (Art 57), Hameln Pharma Gmbh, Pharma Resources Gmbh, Hexal Ag, Hikma Farmacêutica (Portugal), S.A., Stadapharm Gmbh, Fresenius Kabi Deutschland Gmbh, Abz-Pharma Gmbh, Aliud Pharma Gmbh · 29 register entries
- OnsetronDenk Pharma Gmbh & Co. Kg · 1 register entry
- ZofranHexal Ag · 3 register entries
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- EmesetKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 2 register entries
- KemosetDEVA HOLDİNG A.Ş. · 4 register entries
- KemotronTURK İLAÇ VE SERUM SAN. A.Ş. · 2 register entries
- KyronsALTOBİO İLAÇ LTD. ŞTİ. · 4 register entries
- LaufranSM PHARMA İLAÇ SAN. LTD. ŞTİ. · 4 register entries
- NauzexPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
- OnasetTURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş. · 4 register entries
- OndarenVEM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- OnzydPLATİN KİMYA MÜMESSİLLİK VE DIŞ TİC. A.Ş. · 4 register entries
- OsetronHAVER FARMA İLAÇ A.Ş. · 3 register entries
- SantisKAYA BEŞERİ İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- VocheronINCPHARMA İLAÇ SAN. VE TİC. LTD. ŞTİ. · 4 register entries
Show all 17 brand names
- ZoferADEKA İLAÇ SAN. VE TİC. A.Ş. · 6 register entries
- ZofranSANDOZ İLAÇ SAN. VE TİC. A.Ş. · 6 register entries
- ZoltemNOBEL İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
- ZontronMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 4 register entries
- ZophralenDEM İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
Brand names in 27 more European countries
- Belgium
- Ondansetron Ab, Ondansetron Accord Healthcare, Ondansetron B. Braun, Ondansetron B.Braun, Ondansetron Eg, Ondansetron Eugia, Ondansetron Fresenius Kabi, Ondansetron Hikma, Ondansetron Kalceks, Ondansetron Teva, Ondansetron Viatris, Setofilm, Zofran-Zydis, Zofsetron
- Bulgaria
- Zofran, Зондарон, Зофран, Ондансетрон Акорд, Ондансетрон Б. Браун, Ондансетрон Калцекс
- Croatia
- Ondansetron Kalceks, Ondanzetron Kabi, Zofran
- Cyprus
- Ondansetron Accord, Ondansetron Noridem, Zotron
- Czechia
- Novetron, Ondansetron Accord, Ondansetron B. Braun, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Noridem, Ondansetron Teva, Zofran
- Denmark
- Ondansetron "kalceks", Ondansetron "stada", Ondansetron Accord, Ondansetron Accordpharma, Ondansetron Aurobindo, Ondansetron B. Braun, Ondansetron Bluefish, Ondansetron Eql Pharma, Ondansetron Fresenius Kabi, Ondansetron Hameln, Ondansetron Noridem, Ondansetron Orifarm, Ondansetron Pharmathen, Ondansetron Stada, Ondansetron Viatris, Ondantriwa, Setrogen, Zofran
- Estonia
- Ondansetron Accord, Ondansetron Basi, Ondansetron Baxter, Ondansetron Kabi, Ondansetron Kalceks
- Finland
- Ondansetron Accord, Ondansetron Accordpharma, Ondansetron B. Braun, Ondansetron Fresenius Kabi, Ondansetron Hameln, Ondansetron Kalceks, Ondansetron Noridem, Ondansetron Stada, Zofran
- France
- Ondansetron Accord, Ondansetron Arrow, Ondansetron Biogaran, Ondansetron Cristers, Ondansetron Eg, Ondansetron Kabi, Ondansetron Renaudin, Ondansetron Teva, Ondansetron Troikaa, Ondansetron Viatris, Ondansetron Zentiva, Ondansetron Zydus, Setofilm, Zolina, Zophren
- Greece
- Cruzafen, Odasen, Odnatron, Onda, Ondameton, Ondansetron /Kabi, Ondansetron Noridem, Ondansetron/Kalceks, Ondaseprol, Setrodan, Trondamet, Vametal, Vefron, Zetron, Zofron, Zophralen
- Hungary
- Emetron, Ondansetron Kabi, Ondansetron Kalceks, Oroset, Vomita
- Iceland
- Cinveron, Ondansetron Bluefish, Ondansetron Fresenius Kabi, Ondansetron Kalceks, Ondansetron Stada, Ondansetron Viatris, Zofran
- Ireland
- Emizof, Ondansetron Accord Healthcare Ireland, Ondansetron Baxter, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Mcdermott Laboratories, Ondansetron Noridem Enterprises, Ondansetron Syri Pharma, Ondansetron Teva, Ondran, Zofran
- Italy
- Emistop, Ondansetron Accord, Ondansetron B. Braun, Ondansetron Doc, Ondansetron Eg, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Noridem, Ondansetron Teva, Ondansetrone Accord Healthcare, Ondansetrone Aurobindo, Ondansetrone Hikma, Ondansetrone Mylan Generics, Ondansetrone Teva, Setofilm, Zofran
- Latvia
- Emetron, Ondansetron Accord, Ondansetron Basi, Ondansetron Baxter, Ondansetron Kabi, Ondansetron Kalceks
- Lithuania
- Ondansetron Accord, Ondansetron Basi, Ondansetron Baxter, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Stada, Ondansetron Teva, Zofran
- Luxembourg
- Avessaron, Ondansetron B. Braun, Ondansetron Eg, Ondansetron Eugia, Ondansetron Kabi, Zofran, Zofran_zydis
- Malta
- Emytron, Ondansetron Accord Healthcare Ireland, Ondansetron Aurobindo Pharma (Malta), Ondansetron Baxter, Ondansetron Kabi, Ondansetron Kalceks
- Netherlands
- Ondansetron Accord, Ondansetron Aspire, Ondansetron B. Braun, Ondansetron Baxter, Ondansetron Focus Care, Ondansetron Fresenius Kabi, Ondansetron Hameln, Ondansetron Hikma, Ondansetron Hydrochloride Dihydrate Aurobindo, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Noridem, Ondansetron Pch, Zofran
- Norway
- Ondansetron Accord, Ondansetron Accordpharma, Ondansetron Bluefish, Ondansetron Fresenius Kabi, Ondansetron Hameln, Ondansetron Kalceks, Ondansetron Noridem, Ondansetron Stada, Zofran
- Poland
- Atossa, Ondansetron Accord, Ondansetron B. Braun, Ondansetron Baxter, Ondansetron Bluefish, Ondansetron Kabi, Ondansetron Kalceks, Ondansétron Accord, Setronon, Zofran
- Portugal
- Danevon, Emytron, Ondansetrom Accord, Ondansetrom Aurovitas, Ondansetrom Azevedos, Ondansetrom Basi, Ondansetrom Generis, Ondansetrom Germed, Ondansetrom Hikma, Ondansetrom Isab, Ondansetrom Labesfal, Ondansetrom Medlink, Ondansetrom Tolife, Ondansetrom Troikaa, Ondansetron Noridem, Otobrol, Zofran
- Romania
- Ondansetron Aurobindo, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Noridem, Ondasan, Osetron, Zondaron
- Slovakia
- Ondansetron Accord, Ondansetron B. Braun, Ondansetron Kabi, Ondansetron Kalceks, Ondansetron Noridem, Onsetrogen Mylan
- Slovenia
- Ondansetron Accord, Ondansetron Baxter, Ondansetron Kabi, Ondansetron Kalceks, Zofran
- Spain
- Ondansetron Aristo, Ondansetron Fresenius Kabi, Ondansetron Kabi, Ondansetron Normon, Ondansetrón Accord, Ondansetrón Aristo, Ondansetrón Aurovitas, Ondansetrón B. Braun, Ondansetrón Bluefish, Ondansetrón Kern Pharma, Ondansetrón Qualigen, Ondansetrón Serraclinics, Ondansetrón Teva-Ratio, Ondansetrón Viatris, Ondasetron Hikma, Setofilm, Yatrox, Zofran
- Sweden
- Ondansetron Accord, Ondansetron Accordpharma, Ondansetron Aristo, Ondansetron Aurobindo, Ondansetron B. Braun, Ondansetron Bluefish, Ondansetron Eql Pharma, Ondansetron Fresenius Kabi, Ondansetron Hameln, Ondansetron Hexal, Ondansetron Kalceks, Ondansetron Noridem, Ondansetron Orifarm, Ondansetron Stada, Ondansetron Teva, Zofran
EMA – Article 57 product data (EU/EEA), 2026-10-28
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Another question about this substance?
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Sources
- U.S. Food and Drug Administration. Ondansetron Hydrochloride (Aurobindo Pharma Limited) – Prescribing Information, 2025-07-19. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=57578387-1918-4e56-a564-f14fb22340bf
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.