Metronidazole
Anaerobex, Metronidazol B. Braun, Metronidazol Bradex, Metronidazol Hikma · ATC code J01XD01
Also known as: Metronidazol · Brand names: Anaerobex, Metronidazol B. Braun, Metronidazol Bradex, Metronidazol Hikma, Metronidazol Kabi, Metronidazol Vioser, Nidazea, Rozex, Arilin, Metrocreme, Metrogalen, Metrogel, Metrolotion, Metronidazol Al, Metronidazol Aristo …
- Key facts
- Active substance
- Metronidazole
- ATC code
- J01XD01
- Authorisation
- authorised nationally; no central EU authorisation
- Information as of
- 2026-10-27
Boxed warning
WARNING
Metronidazole has been shown to be carcinogenic in mice and rats (see PRECAUTIONS ). Unnecessary use of the drug should be avoided. Its use should be reserved for the conditions described in the INDICATIONS AND USAGE section below.
Key facts
Metronidazole is a nitroimidazole antimicrobial. Per the US label, oral metronidazole is used for trichomoniasis, amebiasis and anaerobic bacterial infections.
What it is used for
- Symptomatic trichomoniasis in females and males, confirmed by laboratory testing
- Asymptomatic trichomoniasis in females with endocervicitis, cervicitis or cervical erosion
- Acute intestinal amebiasis and amebic liver abscess
- Serious anaerobic bacterial infections
Dosing
- Trichomoniasis: one-day treatment of two grams (single or two divided doses) or 250 mg three times daily for seven days
- Acute amebic dysentery, adults: 750 mg three times daily for 5 to 10 days; liver abscess 500 mg or 750 mg three times daily
- Amebiasis, pediatric: 35 to 50 mg/kg/24 hours in three doses for 10 days
- Anaerobic infections, adults: 7.5 mg/kg every six hours, maximum 4 g per 24 hours; usually 7 to 10 days
- Severe hepatic impairment (Child-Pugh C): reduce dose by 50%; hemodialysis guidance in the full text
Contraindications
- Hypersensitivity to metronidazole or other nitroimidazoles
- Trichomoniasis in the first trimester of pregnancy
- Disulfiram use within the last two weeks
- Alcohol or propylene glycol products during and for at least three days after therapy
- Cockayne syndrome
Important warnings
- Boxed warning: carcinogenic in mice and rats; avoid unnecessary use
- Severe cutaneous adverse reactions (TEN, SJS, DRESS, AGEP); discontinue immediately
- Encephalopathy, peripheral and optic neuropathy, convulsive seizures
- QT prolongation, especially with other QT-prolonging drugs
Side effects
- Most common gastrointestinal: nausea, anorexia, vomiting, diarrhea, abdominal cramping
- Metallic taste, glossitis, stomatitis
- Serious: seizures, encephalopathy, aseptic meningitis, neuropathy
- Headache, dizziness, ataxia, confusion; rash, pruritus
Interactions
- Alcohol: disulfiram-like reaction; disulfiram: psychotic reactions
- Warfarin and coumarins: prolonged prothrombin time; monitor INR
- Lithium: serum lithium may rise
Pregnancy and breastfeeding
- Contraindicated for trichomoniasis in the first trimester
- Present in human milk; infant serum levels can approach therapeutic levels
Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.
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For patients
Patient information (US)
This product has no separate US patient information.
Authorisation and brand names by country
Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.
Austria
- AnaerobexG.L. Pharma Gmbh · 2 register entries
- Metronidazol B. BraunB.Braun Melsungen Ag · 1 register entry
- Metronidazol BradexBradex S.A. · 1 register entry
- Metronidazol HikmaHikma Farmacêutica (Portugal), S.A. · 1 register entry
- Metronidazol KabiFresenius Kabi Austria Gmbh · 1 register entry
- Metronidazol VioserVioser S.A. · 1 register entry
- NidazeaDr. August Wolff Gmbh & Co. Kg Arzneimittel · 1 register entry
- RozexGalderma International · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Germany
- ArilinDr. August Wolff Gmbh & Co. Kg Arzneimittel · 3 register entries
- MetrocremeGalderma Laboratorium Gmbh · 1 register entry
- MetrogalenGalenpharma Gmbh · 1 register entry
- MetrogelGalderma Laboratorium Gmbh · 1 register entry
- MetrolotionGalderma Laboratorium Gmbh · 1 register entry
- Metronidazol AlAliud Pharma Gmbh · 1 register entry
- Metronidazol AristoAristo Pharma Gmbh (Art 57) · 1 register entry
- Metronidazol Artesan-DrossapharmDrossapharm Gmbh · 1 register entry
- Metronidazol B. BraunB.Braun Melsungen Ag · 1 register entry
- Metronidazol DeltamedicaDeltamedica Gmbh · 1 register entry
- Metronidazol FreseniusFresenius Kabi Deutschland Gmbh · 1 register entry
- Metronidazol HeumannHeumann Pharma Gmbh & Co. Generica Kg · 1 register entry
Show all 19 brand names
- Metronidazol NoridemNoridem Enterprises Ltd · 1 register entry
- Metronidazol PanpharmaPanpharma Gmbh · 1 register entry
- Metronidazol RatiopharmRatiopharm Gmbh · 1 register entry
- Metronidazol StadaStadapharm Gmbh · 1 register entry
- Metronidazole RatiopharmRatiopharm Gmbh · 1 register entry
- RosicedLaboratoires Bailleul S.A. · 1 register entry
- Vagi - MetroDrossapharm Gmbh · 1 register entry
Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28
Turkey
- AzogylVEM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- Biofleks MetroselOSEL İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- FladazolKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 2 register entries
- Laronium %SM PHARMA İLAÇ SAN. LTD. ŞTİ. · 2 register entries
- MultiflexHAVER FARMA İLAÇ A.Ş. · 2 register entries
- Neofleks %TURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş. · 2 register entries
- NidazolMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 2 register entries
- PolgylPOLİFARMA İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
- Turkfleks %TURK İLAÇ VE SERUM SAN. A.Ş. · 2 register entries
Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16
USA
- FlagylPfizer Laboratories Div Pfizer Inc · 1 register entry
- LikmezKesin Pharma Corporation · 1 register entry
- NoritateBausch Health US, LLC · 1 register entry
- NuvessaExeltis USA, Inc. · 1 register entry
- VandazoleUpsher-smith Laboratories, LLC · 1 register entry
Source: U.S. FDA – Drug labels (openFDA/DailyMed), as of 2026-10-28
Brand names in 27 more European countries
- Belgium
- Flagyl, Metronidazole B. Braun, Metronidazole Noridem, Rozex
- Bulgaria
- Aрилин, Арилин Рапид, Ефлоран, Метроза, Метронидазол Абр, Метронидазол И.В Браун, Полгил
- Croatia
- Arilin Rapid, Efloran, Medazol, Metronidazol B. Braun, Metronidazol Fresenius, Metronidazol Noridem, Metrosa, Rozamet
- Cyprus
- Colpocin-T, Flagymet, Metronidazole, Nidagyl
- Czechia
- Efloran, Entizol, Metronidazol Avmc, Metronidazol B. Braun, Metronidazole Noridem, Metronidazole Polpharma, Rosalox, Rozex
- Denmark
- Metronidazol Actavis, Metronidazol Avia Pharma, Metronidazol B. Braun, Metronidazol Dak, Metronidazol Viaflo Baxter, Metronidazole Noridem, Rozex, Zidoval
- Estonia
- Arilin, Metronidazol Orifarm, Metronidazole Fresenius, Metrosa, Rozex
- Finland
- Arilin, Flagyl, Metronidazole Braun, Metronidazole Noridem, Metronidazole Vioser, Rosazol, Rozex, Trikozol, Zidoval
- France
- Flagyl, Metronidazole B Braun, Metronidazole Bailly-Creat, Metronidazole Baxter, Metronidazole Biogaran, Metronidazole Biosedra, Metronidazole Gerda, Metronidazole Noridem, Metronidazole Sg-Pharm, Metronidazole Substipharm, Métronidazole Arrow, Rozacreme, Rozagel, Rozex
- Greece
- Colpocin-T, Emedal, Flagyl, Flagymet, Flanygrame, Metrogyl, Metronidazole B.Braun, Metronidazole Baxter, Metronidazole Cooper, Metronidazole Norma, Metronidazole Βιοσερ, Robaz, Tricodazole, Unitrim
- Hungary
- Klion, Metronidazol-Human Teva Gyógyszergyár, Metronidazol Noridem, Rozex
- Iceland
- Flagyl, Metronidazol Actavis, Metronidazol Baxter, Metronidazol Normon, Rosazol
- Ireland
- Flagyl, Metronidazole B. Braun Melsungen, Metronidazole Noridem, Rozex
- Italy
- Deflamon, Flagyl, Metronidazole Noridem, Metronidazolo Aurobindo, Metronidazolo B. Braun, Metronidazolo Baxter S.P.A., Metronidazolo Bioindustria Lim, Metronidazolo Kabi, Metronidazolo S.A.L.F., Metronidazolo Same Savoma Medicinali, Rosiced, Rozex, Vagilen, Zidoval
- Latvia
- Arilin, Metronidazol Orifarm, Metronidazole B. Braun, Metronidazole Basi, Metronidazole Fresenius, Metronidazole Unifarma, Metrosa, Rozex, Trichopol
- Lithuania
- Arilin, Metronidazole B.Braun, Metronidazole Basi, Metronidazole Fresenius, Metronidazole Vioser, Metrosa, Supplin, Trichopol
- Luxembourg
- Flagyl, Metronidazol B. Braun, Metronidazole Noridem, Rozex
- Malta
- Metronidazole B. Braun, Metronidazole Remedica, Nidagyl, Rozex
- Netherlands
- Flagyl, Metronidazol Aurobindo, Metronidazol B. Braun, Metronidazol Fresenius, Metronidazol Hikma, Metronidazol In Viaflo Baxter, Metronidazol Noridem, Metronidazole Aurobindo, Metrosa, Rozex
- Norway
- Flagyl, Metronidazol Actavis, Metronidazol Viaflo Baxter, Metronidazole Braun, Metronidazole Noridem, Rosazol, Rozex, Zidoval
- Poland
- Arilin Rapid, Metronidazol Aurovitas, Metronidazol Chema, Metronidazol Fresenius, Metronidazol Jelfa, Metronidazol Polpharma, Metronidazol Ziaja, Metronidazole B. Braun, Rozetic, Rozex, Vilantrin
- Portugal
- Dabenzol, Dumozol, Flagyl, Metroderme, Metronidazol Basi, Metronidazol Braun, Metronidazol Generis, Metronidazol Hikma, Metronidazol Isab, Metronidazol Labesfal, Metronidazol Noridem, Rodermil, Rosiced
- Romania
- Metronidazol Arena, Metronidazol B Infomed Fluids, Metronidazol Braun, Metronidazol Vioser, Metronidazole Noridem
- Slovakia
- Efloran, Entizol, Metronidazol B. Braun, Metronidazole Noridem, Metronidazole Polpharma, Rozex
- Slovenia
- Efloran, Metronidazol Braun, Metronidazol Noridem Enterprises, Rozamet
- Spain
- Flagyl, Intizol Vaginal, Metronidazol Altan, Metronidazol Aurovitas, Metronidazol B. Braun, Metronidazol Normon, Metronidazol Serraclinics, Metronidazol Viñas, Metronidazole Noridem, Rozex
- Sweden
- Flagyl, Metronidazol Actavis, Metronidazol Eql Pharma, Metronidazole Basi, Metronidazole Braun, Metronidazole Noridem, Rosazol, Rozex, Zidoval
EMA – Article 57 product data (EU/EEA), 2026-10-28
Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.
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Sources
- U.S. Food and Drug Administration. Metronidazole (BluePoint Laboratories) – Prescribing Information, 2026-02-23. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=3cf021b6-5794-4a86-b09d-bece0ba8b302
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
- TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
- U.S. FDA – Drug labels (openFDA/DailyMed), 2026-10-28. https://dailymed.nlm.nih.gov/dailymed/
Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error
Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.