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Lenalidomide

Revlimid · ATC code L04AX04

Also known as: Lenalidomid · Brand names: Revlimid, Lenalidomid +pharma, Lenalidomid Biocon, Lenalidomid Fresenius Kabi, Lenalidomid G.L., Lenalidomid Grindeks, Lenalidomid Sandoz, Lenalidomid Stada, Lenalidomid Teva, Lenalidomid Zentiva, Lenabdor, Komplia, Lenatu, Lenom, Paused …

Key facts
Active substance
Lenalidomide
Drug class
Immunosuppressive drug
ATC code
L04AX04
Authorisation
centrally authorised across the EU (EMA)
Dosage forms
Revlimid 2.5 mg hard capsules / Revlimid 5 mg hard capsules / Revlimid 7.5 mg hard capsules
Marketing authorisation holder
Bristol-Myers Squibb Pharma EEIG
Information as of
2026-10-27

Key facts

Lenalidomide (Revlimid) is an immunomodulatory agent structurally related to thalidomide, used for multiple myeloma, certain myelodysplastic syndromes, and mantle cell and follicular lymphoma.

What it is used for

  • Multiple myeloma: maintenance after autologous stem cell transplantation; untreated, transplant-ineligible in combination; after at least one prior therapy with dexamethasone
  • Transfusion-dependent anaemia due to low- or intermediate-1-risk MDS with isolated deletion 5q
  • Relapsed or refractory mantle cell lymphoma
  • Previously treated follicular lymphoma (Grade 1–3a) with rituximab

Dosing

  • Myeloma with dexamethasone (transplant-ineligible): 25 mg once daily on days 1 to 21 of 28-day cycles; dexamethasone 40 mg on days 1, 8, 15 and 22
  • MDS: 10 mg once daily on days 1 to 21 of 28-day cycles
  • Stepwise dose reduction for Grade 3 or 4 toxicity (tables in full text)
  • Renal impairment: adjustment from moderate impairment (table in full text)
  • Missed dose: take within 12 hours, otherwise skip
  • Other regimens by indication in the full text

Contraindications

  • Hypersensitivity to the active substance or any excipient
  • Pregnancy
  • Women of childbearing potential unless all conditions of the Pregnancy Prevention Programme are met

Important warnings

  • Teratogenic effect expected; Pregnancy Prevention Programme mandatory for all patients
  • Neutropenia and thrombocytopenia are the major dose-limiting toxicities; monitor blood counts
  • Increased risk of venous and arterial thromboembolism, especially with dexamethasone
  • Second primary malignancies observed

Side effects

  • Maintenance: neutropenia, bronchitis, diarrhoea, nasopharyngitis, muscle spasms, leucopenia, asthenia, cough, thrombocytopenia
  • Serious: pneumonia and lung infection

Interactions

  • Erythropoietic agents and hormone replacement therapy increase thrombosis risk
  • Digoxin: increased exposure, monitoring advised
  • Statins: increased risk of rhabdomyolysis; warfarin: close monitoring
  • Combined oral contraceptives not recommended

Pregnancy and breastfeeding

  • Women of childbearing potential: effective contraception at least 4 weeks before, during and at least 4 weeks after therapy
  • Treatment must be stopped if pregnancy occurs

Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

Common questions – ask Medelix

For patients

Package leaflet, verbatim

Package leaflet for patients →

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

EU – centrally authorised (all member states)

Source: European Medicines Agency (EMA), product information

Austria

  • Lenalidomid +pharma+pharma Arzneimittel Gmbh · 1 register entry
  • Lenalidomid BioconBiocon Pharma Malta I Limited · 1 register entry
  • Lenalidomid Fresenius KabiFresenius Kabi Austria Gmbh · 1 register entry
  • Lenalidomid G.L.G.L. Pharma Gmbh · 1 register entry
  • Lenalidomid GrindeksGrindeks · 1 register entry
  • Lenalidomid SandozSandoz Gmbh · 1 register entry
  • Lenalidomid StadaStada Arzneimittel Gmbh · 1 register entry
  • Lenalidomid TevaTeva B.V · 1 register entry
  • Lenalidomid ZentivaZentiva, K.S. · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Germany

  • LenabdorTad Pharma Gmbh · 1 register entry
  • Lenalidomid123 Acurae Pharma Gmbh, Ratiopharm Gmbh, Medical Valley Invest Ab, Grindeks, Devatis Gmbh, Zentiva Pharma Gmbh, Amarox Pharma Gmbh, Basics Gmbh, Biocon Pharma Malta I Limited, Hexal Ag, Olpha As, Eugia Pharma (Malta) Limited, Stadapharm Gmbh, Qilu Pharma Spain S.L., Abz-Pharma Gmbh, Aliud Pharma Gmbh · 16 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Turkey

  • KompliaTURGUT İLAÇLARI A.Ş. · 4 register entries
  • LenatuONKO İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
  • LenomWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • PausedARVEN İLAÇ SAN. VE TİC. A.Ş. · 5 register entries
  • RelivABDİ İBRAHİM İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • RevdominELH İLAÇ SAN. TİC. LTD. ŞTİ · 4 register entries
  • RevlimidBRISTOL-MYERS SQUIBB İLAÇLARI INC. İSTANBUL ŞUBESİ · 8 register entries
  • RivelimeDEVA HOLDİNG A.Ş. · 8 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

Brand names in 28 more European countries
Belgium
Lenalidomid Grindeks, Lenalidomide Eg, Lenalidomide Eugia, Lenalidomide Grindeks, Lenalidomide Sandoz
Bulgaria
Lenalidomide Sandoz, Леналидомид Алкалоид-Инт, Леналидомид Гриндекс
Croatia
Lenalidomid Alkaloid-Int, Lenalidomid Grindeks, Lenalidomid Teva, Lenalidomid Zentiva
Cyprus
7,5, Lenalidomide Grindeks, Lenalidomide Norameda, Lenalidomide Stada, Myelomide
Czechia
Lenalidomid Sandoz, Lenalidomid Stada, Lenalidomid Teva, Lenalidomid Zentiva, Lenalidomide Glenmark, Lenalidomide Grindeks
Denmark
Lenalidomid Grindeks, Lenalidomid Medical Valley, Lenalidomid Stada Nord, Lenalidomid Stada Nordic, Lenalidomid Sun, Lenalidomid Zentiva, Lenalidomide Glenmark, Lenalidomide Sandoz, Lenalidomide Stada, Lenalidomide Teva
Estonia
Lenalidomide Auxilia, Lenalidomide Grindeks
Finland
Ferulinor Stada, Lenalidomid Avansor, Lenalidomid Zentiva, Lenalidomide Grindeks, Lenalidomide Ratiopharm, Lenalidomide Sandoz, Lenalidomide Stada
France
Lenalidomide Arrow, Lenalidomide Eg, Lenalidomide Grindeks, Lenalidomide Olpha, Lenalidomide Stragen, Lenalidomide Sun, Lenalidomide Teva, Lenalidomide Zentiva
Greece
Cortedal, Lenalidomide, Myelomide, Renalyd
Hungary
Lenalidomid Teva, Lenalidomide Grindeks, Lenalidomide Sandoz, Lenalidomide Stada, Lenalidomide Zentiva, Lignaron
Iceland
Cortedal, Ferulinor, Kleder, Lenalidomid Medical Valley, Lenalidomid Wh, Lenalidomid Zentiva, Lenalidomide Accord, Lenalidomide G.L., Lenalidomide Grindeks, Lenalidomide Krka, Lenalidomide Mylan, Lenalidomide Sandoz, Lenalidomide Stada, Lenalidomide Teva, Lignaron, Revlimid, Vumavel, Zelvina
Ireland
Lenalidomide Clonmel, Lenalidomide Grindeks, Lenalidomide Rowex, Lenalidomide Teva
Italy
Kleder, Lenalidomide Aurobindo, Lenalidomide Biocon, Lenalidomide Glenmark, Lenalidomide Grindeks, Lenalidomide Olpha, Lenalidomide Qilu, Lenalidomide Sandoz, Lenalidomide Sun, Lenalidomide Teva, Lenalidomide Zentiva
Latvia
Lenalidomide Grindeks, Lenalidomide Norameda, Lenalidomide Stada, Lenalidomide Zentiva
Liechtenstein
Lenalidomide Accord, Lenalidomide Mylan, Revlimid
Lithuania
Lenalidomide G.L., Lenalidomide Grindeks, Lenalidomide Norameda, Lenalidomide Stada, Lenalidomide Zentiva
Luxembourg
Lenalidomide
Malta
Lenalidomida Generis, Lenalidomide Generis, Lenalidomide Grindeks, Zelvina
Netherlands
Lenalidomide Alkaloid-Int, Lenalidomide Amarox, Lenalidomide Anabiosis, Lenalidomide Biocon, Lenalidomide Devatis, Lenalidomide Eugia, Lenalidomide Fresenius Kabi, Lenalidomide Genthon, Lenalidomide Glenmark, Lenalidomide Grindeks, Lenalidomide Olpha, Lenalidomide Rafarm, Lenalidomide Ratiopharm, Lenalidomide Sandoz, Lenalidomide Synthon, Lenalidomide Teva
Norway
Ferulinor, Lenalidomid Medical Valley, Lenalidomid Sun, Lenalidomid Zentiva, Lenalidomide Accord, Lenalidomide Grindeks, Lenalidomide Krka, Lenalidomide Mylan, Lenalidomide Sandoz, Lenalidomide Teva, Revlimid
Poland
Kleder, Lenalidomide Eugia, Lenalidomide Grindeks, Lenalidomide Medical Valley, Lenalidomide Ranbaxy, Lenalidomide Sandoz, Lenalidomide Zentiva, Lenalidomidum Stada Arzneimittel Ag, Polalid
Portugal
Lenalidomida Biocon, Lenalidomida Generis, Lenalidomida Grindeks, Lenalidomida Mecapharma, Lenalidomida Pharmakern, Lenalidomida Sandoz, Lenalidomida Stada, Lenalidomida Tecnigen, Lenalidomida Teva, Lenalidomida Zentiva
Romania
Lenalidomidă Alkaloid-Int, Lenalidomidă Grindeks, Lenalidomidă Labormed, Lenalidomidă Sandoz, Lenalidomidă Stada, Lenalidomidă Terapia, Lenalidomidă Teva
Slovakia
Lenalidomid Glenmark, Lenalidomid Grindeks, Lenalidomid Pharmevid, Lenalidomid Sandoz, Lenalidomid Stada, Lenalidomid Teva B.V., Lenalidomid Zentiva, Lignaron
Slovenia
Lenabdor, Lenalidomid Alkaloid-Int, Lenalidomid Grindeks, Lenalidomid Hcs, Lenalidomid Sandoz, Lenalidomid Teva
Spain
Lenalidomida Aurovitas, Lenalidomida Grindeks, Lenalidomida Kern Pharma, Lenalidomida Olpha, Lenalidomida Qilu, Lenalidomida Sandoz, Lenalidomida Stada, Lenalidomida Sun, Lenalidomida Tarbis, Lenalidomida Tecnigen, Lenalidomida Teva
Sweden
Ferulinor, Lenalidomid Avansor, Lenalidomid Medical Valley, Lenalidomid Sun, Lenalidomid Zentiva, Lenalidomide Glenmark, Lenalidomide Grindeks, Lenalidomide Sandoz, Lenalidomide Stada, Lenalidomide Teva

EMA – Article 57 product data (EU/EEA), 2026-10-28

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Sources

  1. European Medicines Agency. Revlimid – EPAR, Product Information (OF THE TEXT Detailed information on this medicinal product i). 2026-10-27. https://www.ema.europa.eu/en/documents/product-information/revlimid-epar-product-information_en.pdf
  2. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  3. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
  5. Wikidata (CC0): ATC L04AX.

Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error

Source: European Medicines Agency (EMA), product information. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.