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Clindamycin

Clindac, Clindamycin, Dalacin, Zindaclin · ATC code J01FF01

Also known as: Klindamisin · Brand names: Clindac, Dalacin, Zindaclin, Clinda-Ipp, Clinda-Saar, Clindafanal, Clindahexal, Clindasol, Clindastad, Sobelin, Biocline, Cleocin, Clin, Klindan, Klindaver …

Key facts
Active substance
Clindamycin
Drug class
Lincosamides
ATC code
J01FF01
Authorisation
authorised nationally; no central EU authorisation
Information as of
2026-10-27

Boxed warning

Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin hydrochloride and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon, leading to overgrowth of C. difficile.
Because clindamycin hydrochloride therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the INDICATIONS AND USAGE section. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections.
C. difficileproduces toxins A and B, which contribute to the development of CDAD. Hypertoxin producing strains of C. difficilecause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. difficilemay need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.

Key facts

Clindamycin is a lincosamide antibiotic. Per the US prescribing information, the capsules are used for serious infections caused by susceptible anaerobes, streptococci, pneumococci and staphylococci.

What it is used for

  • Serious infections caused by susceptible anaerobic bacteria (e.g., respiratory tract, skin and soft tissue, septicemia, intra-abdominal, female pelvis)
  • Serious infections due to streptococci, pneumococci and staphylococci, reserved for penicillin-allergic patients or when a penicillin is inappropriate
  • Reserved for serious infections because of the colitis risk; not for nonbacterial infections

Dosing

  • Adults, serious infections: 150 to 300 mg every 6 hours; more severe infections: 300 to 450 mg every 6 hours
  • Pediatric patients able to swallow capsules: 8 to 16 mg/kg/day, more severe infections 16 to 20 mg/kg/day, divided into three or four equal doses
  • Dosed on total body weight regardless of obesity
  • Taken with a full glass of water and at least 30 minutes before lying down
  • β-hemolytic streptococcal infections: treat for at least 10 days

Contraindications

  • History of hypersensitivity to clindamycin or lincomycin

Important warnings

  • Boxed warning: Clostridioides difficile-associated diarrhea (CDAD), up to fatal colitis, even over two months after treatment
  • Discontinue if significant diarrhea occurs during therapy
  • Anaphylactic shock and severe hypersensitivity reactions
  • Severe skin reactions including toxic epidermal necrolysis

Side effects

  • Most frequent: mild to moderate morbilliform (maculopapular) rashes
  • Abdominal pain, nausea, vomiting, diarrhea, pseudomembranous colitis
  • Esophagitis and esophageal ulcer, metallic taste
  • Jaundice, abnormal liver function tests, acute kidney injury
  • Severe skin reactions (TEN, AGEP, erythema multiforme), anaphylaxis

Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

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For patients

Patient information (US)

This product has no separate US patient information.

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

Austria

  • ClindacSandoz Gmbh · 1 register entry
  • Clindamycin1a Pharma Gmbh, Teva B.V, Kalceks, Noridem Enterprises Ltd, Hameln Pharma Gmbh, Mip Pharma Austria Gmbh · 8 register entries
  • DalacinPfizer Corporation Austria Ges.M.B.H. · 4 register entries
  • ZindaclinAspire Pharma (Malta) Limited · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Germany

  • Clinda-IppMip Pharma Gmbh · 1 register entry
  • Clinda-SaarChephasaar Chemisch-Pharmazeutische Fabrik Gmbh · 2 register entries
  • ClindafanalDr. Pfleger Arzneimittel Gmbh · 1 register entry
  • ClindahexalHexal Ag · 2 register entries
  • Clindamycin1 A Pharma Gmbh, Ratiopharm Gmbh, Kalceks, Noridem Enterprises Ltd, Aristo Pharma Gmbh (Art 57), Dr. Friedrich Eberth Arzneimittel Gmbh, Hameln Pharma Gmbh, Hexal Ag, Hikma Farmacêutica (Portugal), S.A., Fresenius Kabi Deutschland Gmbh, Mip Pharma Gmbh, Aliud Pharma Gmbh · 17 register entries
  • ClindasolCnp Pharma Gmbh · 2 register entries
  • ClindastadStadapharm Gmbh · 1 register entry
  • SobelinPfizer Pharma Gmbh · 5 register entries
  • ZindaclinInfectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim · 2 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Turkey

  • BioclineFARMALAS İLAÇ SAN. VE TİC. LTD. ŞTİ. · 2 register entries
  • CleocinPFİZER PFE İLAÇLARI A.Ş. · 2 register entries
  • ClinMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 3 register entries
  • KlindanBİLİM İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • KlindaverOSEL İLAÇ SAN. VE TİC. A.Ş. · 6 register entries
  • KlitopsinTOPRAK İLAÇ VE KİMYEVİ MADDELER SAN.VE TİC. A.Ş. · 3 register entries
  • MeneklinTÜM-EKİP İLAÇ A.Ş. · 6 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

USA

  • CleocinPharmacia & Upjohn Company LLC · 1 register entry
  • Cleocin PhosphatePharmacia & Upjohn Company LLC, Medical Purchasing Solutions, LLC, ProPharma Distribution · 4 register entries
  • Cleocin TPharmacia & Upjohn Company LLC · 1 register entry
  • Clindacin PEurofarma, Inc. · 1 register entry
  • XaciatoOrganon LLC · 1 register entry

Source: U.S. FDA – Drug labels (openFDA/DailyMed), as of 2026-10-28

Brand names in 27 more European countries
Belgium
Clindamycin Noridem, Clindamycin Sandoz, Clindamycine Eg, Clindamycine Fresenius Kabi, Dalacin C, Dalacin Vaginal, Yenlip, Zindaclin
Bulgaria
Clindamycin Kabi, Далацин C, Клиндавазин B, Клиндавазин Д, Клиндамицин Mip, Клиндамицин Xамелн, Клиндамицин Абр
Croatia
Aknet, Dalacin, Damklin, Klimicin, Klindamicin Hameln, Klindamicin Kalceks, Klindamicin Mip
Cyprus
Arfarel, Clindamycin Abr, Clindamycin Noridem Noridem, Clindamycin Normon, Dalacin C, Fouch, Yenlip
Czechia
Clindamycin Hameln, Clindamycin Kabi, Clindamycin Noridem, Dalacin, Klimicin
Denmark
Clindamycin Abcur, Clindamycin Alternova, Clindamycin Hameln, Clindamycin Kalceks, Clindamycin Navamedic, Clindamycin Noridem, Clindamycin Terix, Dalacin
Estonia
Clindamycin Mip, Dalacin
Finland
Clindamycin Abcur, Clindamycin Fresenius Kabi, Clindamycin Kalceks, Clindamycin Mip, Clindamycin Navamedic, Clindamycin Noridem, Clindamycin Orion, Clindamycin Sanoswiss, Dalacin
France
Clindamycine Kabi, Clindamycine Kalceks, Clindamycine Mip, Clindamycine Noridem, Clindamycine Substipharm, Clindamycine Viatris, Dalacine, Zindacline
Greece
Cleo-Fort, Clidacin, Climycen, Clindagel, Clindamycin, Dalacin C, Edason, Esteria, Fouch, Sotomycin, Toliken, Upderm, Vagiclin, Veldom, Velkaderm, Yenlip, Ygielle
Hungary
Clindamycin Anfarm, Clindamycin Hameln, Clindamycin Kabi, Clindamycin Kalceks, Dalacin, Klimicin, Klindamicin Noridem, Zindaclin
Iceland
Clindamycin Abcur, Clindamycin Eql Pharma, Dalacin
Ireland
Clindamycin, Dalacin, Zindaclin
Italy
Cleocin, Clindamicina Fosfato Bioindustria L.I.M., Clindamicina Fosfato Hikma, Clindamicina Kalceks, Clindamicina Noridem, Clindamicina Same, Clindax, Dalacin C, Dalacin T, Zindaclin
Latvia
Clindamycin Kalceks, Clindamycin Mip, Dalacin
Lithuania
Clindamycin Mip, Dalacin C
Luxembourg
Clindamycine Eg, Clindamycine Fresenius Kabi, Dalacin C, Dalacin Vaginal, Yenlip
Malta
Clidacin Ba Free Amp, Clindamicina Accord, Clindamycin Anfarm, Dalacin C
Netherlands
Clindamycin Teva, Clindamycine Added Pharma, Clindamycine Cf, Clindamycine Double-E Pharma, Clindamycine Fresenius Kabi, Clindamycine Hameln, Clindamycine Kalceks, Clindamycine Lotion Fna Tiofarma, Clindamycine Noridem, Clindamycine Sandoz, Clindamycine Teva, Dalacin C
Norway
Clindamycin Abcur, Clindamycin Kalceks, Clindamycin Navamedic, Clindamycin Noridem, Dalacin
Poland
Clindacne, Clindalin, Clindamycin Hameln, Clindamycin Kabi, Clindamycin Mip, Clindamycin Noridem, Clindanea, Clindavag, Dalacin C, Dalacin T, Klimicin, Klindacin T, Normaclin, Symbactin
Portugal
Clincina, Clindamicina Generis, Clindamicina Labesfal, Clindamicina Noridem, Dalacin C, Dalacin V, Zindaclin
Romania
Clindamicină Hameln, Clindamycin Mip, Clindamycin Noridem, Clindamycin Stada Hemofarm, Dalacin C, Ovyx
Slovakia
Clindamycin Hameln, Clindamycin Kabi, Clindamycin Noridem, Dalacin C, Dalacin T, Dalacin V, Klimicin
Slovenia
Dalacin, Klimicin, Klindamicin Hameln, Klindamicin Kalceks
Spain
Clindamicina Aristo, Clindamicina Kalceks, Clindamicina Normon, Clindamicina Qualigen, Clinwas, Dalacin, Zindaclin
Sweden
Clindamycin Abcur, Clindamycin Actavis, Clindamycin Eql Pharma, Clindamycin Hameln, Clindamycin Navamedic, Clindamycin Noridem, Clindamycin Orifarm, Dalacin, Klindamycin Evolan

EMA – Article 57 product data (EU/EEA), 2026-10-28

Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.

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Sources

  1. U.S. Food and Drug Administration. Clindamycin Hydrochloride (VERITYRX, LLC) – Prescribing Information, 2025-10-31. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=427a0138-c2dd-cf0b-e063-6394a90af407
  2. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  3. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
  5. U.S. FDA – Drug labels (openFDA/DailyMed), 2026-10-28. https://dailymed.nlm.nih.gov/dailymed/
  6. Wikidata (CC0): ATC J01FF.

Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error

Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.