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Clarithromycin

Clarithromycin, Klacid · ATC code J01FA09

Also known as: Klaritromisin · Brand names: Klacid, Clarilind, Pro, Clabel, Claricide, Clarol, Cleanomisin, Deklarit, Denta-Clar, Inclar, Klamaxin, Klamer, Klarimax, Klaritromisin - Haver, Klarolid …

Key facts
Active substance
Clarithromycin
Drug class
Macrolide antibiotic
ATC code
J01FA09
Authorisation
authorised nationally; no central EU authorisation
Information as of
2026-10-27

Key facts

Clarithromycin is a macrolide antibacterial used for mild to moderate bacterial infections, H. pylori eradication and Mycobacterium avium disease.

What it is used for

  • Acute bacterial exacerbation of chronic bronchitis, acute maxillary sinusitis, community-acquired pneumonia
  • Pharyngitis/tonsillitis (as an alternative), uncomplicated skin and skin structure infections, acute otitis media
  • Treatment and prophylaxis of disseminated Mycobacterium avium disease
  • H. pylori eradication to reduce the risk of duodenal ulcer recurrence (in combination)

Dosing

  • May be given with or without food
  • Adults: 250 to 500 mg every 12 hours for 7 to 14 days depending on infection (e.g. sinusitis 500 mg for 14 days)
  • H. pylori triple therapy: 500 mg clarithromycin with amoxicillin 1 gram and lansoprazole 30 mg or omeprazole 20 mg, every 12 hours
  • Children: 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose)
  • Severe renal impairment (CLcr < 30 mL/min): dosage reduced by 50%; further adjustments with atazanavir or ritonavir

Contraindications

  • Hypersensitivity to clarithromycin, erythromycin or other macrolides
  • Concomitant cisapride, pimozide, ergotamine/dihydroergotamine, lurasidone, lomitapide, lovastatin or simvastatin
  • History of cholestatic jaundice or hepatic dysfunction with prior clarithromycin
  • Colchicine in patients with renal or hepatic impairment

Important warnings

  • Severe acute hypersensitivity reactions (e.g. anaphylaxis, SJS, TEN, DRESS): discontinue immediately
  • QT prolongation and torsades de pointes; avoid with QT prolongation, hypokalemia/hypomagnesemia, bradycardia or Class IA/III antiarrhythmics
  • Hepatotoxicity including fatal hepatic failure; discontinue if hepatitis develops
  • Clostridium difficile-associated diarrhea; exacerbation of myasthenia gravis
  • Serious adverse reactions due to concomitant use with other drugs

Side effects

  • Most frequent: abdominal pain, diarrhea, nausea, vomiting and dysgeusia
  • Also: dyspepsia, abnormal liver function tests, candidiasis, headache, insomnia, rash
  • Anaphylactic reaction reported

Interactions

  • Inhibits CYP3A: increased levels of CYP3A substrates (e.g. carbamazepine); dose adjustment and concentration monitoring
  • Drugs that prolong the QT interval should be avoided
  • Numerous contraindicated combinations (see contraindications)

Pregnancy and breastfeeding

  • Based on animal studies, not recommended in pregnancy except where no alternative therapy is appropriate

Summary of the official product information, written with AI (Claude, Anthropic) on 2026-10-28. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

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For patients

Patient information (US)

This product has no separate US patient information.

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

Austria

  • Clarithromycin1a Pharma Gmbh, Teva B.V, Accord Healthcare B.V., Hameln Pharma Gmbh, Sandoz Gmbh, Hikma Farmacêutica (Portugal), S.A., Stada Arzneimittel Gmbh, Krka, D.D., Novo Mesto · 8 register entries
  • KlacidViatris Austria Gmbh, Viatris Healthcare Limited · 3 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Germany

  • ClarilindAristo Pharma Gmbh (Art 57) · 1 register entry
  • Clarithromycin1 A Pharma Gmbh, Micro Labs Gmbh, Hec Pharm Gmbh, Tillomed Pharma Gmbh, Noridem Enterprises Ltd, Basics Gmbh, Hameln Pharma Gmbh, Hexal Ag, Hikma Farmacêutica (Portugal), S.A., Stadapharm Gmbh, Aliud Pharma Gmbh · 15 register entries
  • KlacidViatris Healthcare Gmbh · 5 register entries
  • ProAliud Pharma Gmbh, Stadapharm Gmbh · 2 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-28

Turkey

  • ClabelNOBEL İLAÇ PAZARLAMA VE SAN. LTD. ŞTİ., NOBEL İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • ClaricideBİLİM İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • ClarolVEM İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
  • CleanomisinRECORDATİ İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
  • DeklaritDEVA HOLDİNG A.Ş. · 5 register entries
  • Denta-ClarDROGSAN İLAÇLARI SAN. VE TİC. A.Ş. · 4 register entries
  • InclarINCPHARMA İLAÇ SAN. VE TİC. LTD. ŞTİ. · 1 register entry
  • KlacidABBOTT LABORATUARLARI İTHALAT İHRACAT VE TİC. LTD. ŞTİ. · 8 register entries
  • KlamaxinMENARİNİ SAĞLIK VE İLAÇ SAN. TİC. A.Ş. · 7 register entries
  • KlamerATABAY KİMYA SAN. VE TİC. A.Ş. · 7 register entries
  • KlarimaxORBİS PHARMA İLAÇ VE KİMYA KOZMETİK MEDİKAL SAN. TİC. LTD. ŞTİ. · 2 register entries
  • Klaritromisin - HaverHAVER TRAKYA İLAÇ SAN. VE TİC. A.Ş. · 1 register entry
Show all 21 brand names
  • KlarolidBERAT BERAN İLAÇ SAN. VE TİC. LTD. ŞTİ. · 2 register entries
  • KlarominAVİXA İLAÇ SAN. VE TİC. A.Ş. · 7 register entries
  • KlaxTOPRAK İLAÇ VE KİMYEVİ MADDELER SAN.VE TİC. A.Ş. · 5 register entries
  • LaricidBİOFARMA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • MacrolSANOVEL İLAÇ SAN. VE TİC. A.Ş. · 9 register entries
  • MaxiclarKOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. · 3 register entries
  • MegasidACTAVİS İLAÇLARI A.Ş. · 3 register entries
  • OradroWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • UniklarLİLYUM İLAÇ VE KİMYA SAN. TİC. LTD. ŞTİ. · 6 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

Brand names in 27 more European countries
Belgium
Biclar, Clarithromycin Krka, Clarithromycin Sandoz, Clarithromycine Eg, Clarithromycine Sandoz, Clarithromycine Viatris, Heliclar, Maclar
Bulgaria
Lekoklar, Oрадро, Клабакс, Клацар, Клацид, Клеримед, Лекоклар, Фромилид
Croatia
Fromilid, Klaritromicin Krka, Lekoklar Xl, Makcin
Cyprus
Clarem, Claripen, Clarithromycin Aurobindo, Klerimed, Rithroclad
Czechia
Clarithromycin Hameln, Clarithromycin Teva, Fromilid, Klabax, Klacid
Denmark
Clarithromycin Accord, Clarithromycin Alternova, Clarithromycin Hexal, Clarithromycin Krka, Clarithromycin Pcd, Clarithromycin Teva, Clarithromycin ”hameln”, Klacid
Estonia
Fromilid, Klabax, Klacid, Klerimed, Lekoklar
Finland
Clarithromycin Hexal, Clarithromycin Krka, Klacid, Zeclar
France
Clarithromycin Teva, Clarithromycine Abbott, Clarithromycine Accord, Clarithromycine Almus, Clarithromycine Arrow, Clarithromycine Biogaran, Clarithromycine Biphar, Clarithromycine Cristers, Clarithromycine Eg, Clarithromycine Evolugen, Clarithromycine Hcs, Clarithromycine Sandoz, Clarithromycine Sun, Clarithromycine Teva, Clarithromycine Viatris, Clarithromycine Zydus, Zeclar
Greece
Clarimex, Claripen, Clarithrocin, Claromycin, Eliben, Ezumycin, Geromycin, Glartin, Klarexyl, Klaribros, Klaricid, Klarifar, Klarithrin, Klaroxin, Klazidem, Larithro, Laromin, Lyoclar, Macladin, Maxigan, Maxilin, Mepires, Odycin, Riclemed, Rithroprol, Sanicet, Sythro, Tromypen, Viaclar, Viaclar®, Κlarifect
Hungary
Clarithromycin, Fromilid, Klabax, Klacid
Iceland
Clarithromycin Krka
Ireland
Clarithromycin Accord Healthcare Ireland, Clarithromycin Amdipharm Limited, Clarithromycin Krka, Clarithromycin N.A., Clarithromycin Noridem Enterprises, Clarithromycin Sun Pharmaceutical Industries Europe, Clarithromycin Teva, Clonocid, Clorom, Klacid
Italy
Clamodin, Claritrol, Claritromicina Accord, Claritromicina Almus, Claritromicina Altan, Claritromicina Alter, Claritromicina Doc Generici, Claritromicina Eg, Claritromicina Hcs, Claritromicina Hexal, Claritromicina Hikma, Claritromicina Mylan Generics, Claritromicina Ranbaxy Italia, Claritromicina Sandoz, Claritromicina Sun Pharma Italia Srl, Claritromicina Teva, Claritromicina Tillomed, Claritromicina Zentiva, Clarmac, Klacid, Kruklar, Macladin, Veclam
Latvia
Clarithromycin Ingen Pharma, Clarithromycin Teva, Clarithromycin Unifarma, Fromilid, Klacid, Klerimed
Lithuania
Clarithromycin Ingen Pharma, Clarithromycin Teva, Fromilid, Klacid, Klerimed, Lekoklar
Luxembourg
Biclar, Clarithromycine Eg, Clarithromycine Viatris, Heliclar, Maclar
Malta
Clarem, Clarithromycin Accord Healthcare, Clarithromycin Aurobindo Pharma (Malta), Clarithromycin Clonmel, Clarithromycin Ibigen, Claromycin, Clonocid, Fromilid, Klacid, Klerimed, Maxilin
Netherlands
Clarithromycin Aurobindo, Claritromycine Accord, Claritromycine Doc Generici, Claritromycine Sandoz, Claritromycine Sun, Claritromycine Teva, Klacid Sr
Norway
Clarithromycin Accord, Clarithromycin Teva, Klacid
Poland
Clarithromycin Adamed, Clarithromycin Hameln, Fromilid, Klabax, Klabion Uno, Klacid, Klarmin, Lekoklar, Taclar
Portugal
Claritromicina, Klacid
Romania
Fromilid, Klabax, Klacid, Lekoklar, Roclarin
Slovakia
Clarithromycin Hameln, Fromilid, Klabax, Klacid, Klerimed, Lekoklar
Slovenia
Fromilid
Spain
Claritromicina Accord, Claritromicina Almus, Claritromicina Altan, Claritromicina Alter, Claritromicina Aurovitas, Claritromicina Brown & Burk, Claritromicina Cinfa, Claritromicina Codramol Farmalider S.A., Claritromicina Farmalider, Claritromicina Kern Pharma, Claritromicina Krka, Claritromicina Normon, Claritromicina Sandoz, Claritromicina Sun, Claritromicina Tarbis, Claritromicina Tecnigen, Claritromicina Unidía Kern Pharma, Claritromicina Viatris, Claritromicina Vir, Klacid
Sweden
Clarithromycin Krka, Klacid

EMA – Article 57 product data (EU/EEA), 2026-10-28

Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.

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Sources

  1. U.S. Food and Drug Administration. Clarithromycin (Rising Pharma Holdings, Inc.) – Prescribing Information, 2024-01-05. DailyMed (NLM), 2026-10-27. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=0c4db97f-f4c9-4cac-9f12-9db1d967ebeb
  2. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  3. EMA – Article 57 product data (EU/EEA), 2026-10-28. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
  5. Wikidata (CC0): ATC J01FA.

Editorial: Medelix editorial team · last updated 2026-10-27 · How these pages are made · Report an error

Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.