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Cefixime

Cefixim Nectar, Sorcelif, Tricef · ATC code J01DD08

Also known as: Cefixim Anhydrat, Sefiksim · Brand names: Cefixim Nectar, Sorcelif, Tricef, Cefixim Al, Cefixim Aristo, Cefixim Hexal, Cefixim Reiwa Healthcare, Cefixim Stada, Cefixim Viatris, Cefixime Hexal, Infectoopticef Saft, Cefdia, Cefixima, Cephix, Fixef …

Key facts
Active substance
Cefixime
Drug class
Cephalosporin antibiotic
ATC code
J01DD08
Authorisation
authorised nationally; no central EU authorisation
Information as of
2026-10-29

Key facts

Cefixime is, per the US prescribing information, an oral cephalosporin antibiotic used to treat bacterial infections such as urinary tract infections, otitis media, pharyngitis and uncomplicated gonorrhea.

What it is used for

  • Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis.
  • Otitis media, pharyngitis and tonsillitis, and acute exacerbations of chronic bronchitis caused by susceptible organisms.
  • Uncomplicated gonorrhea (cervical/urethral).
  • Each in adults and children six months of age or older.

Dosing

  • Adults: 400 mg daily, e.g. as one 400 mg capsule; uncomplicated cervical/urethral gonorrhea: a single 400 mg dose; may be taken without regard to food.
  • Children 6 months or older: 8 mg/kg/day of suspension, once daily or as 4 mg/kg every 12 hours; weight-based dose table in the full text; children over 45 kg or older than 12 years receive the adult dose.
  • Otitis media should be treated with the suspension; tablets or capsules should not be substituted.
  • Streptococcus pyogenes infections: treat for at least 10 days.
  • Renal impairment: normal dose at creatinine clearance of 60 mL/min or greater; lower doses below that and on hemodialysis or peritoneal dialysis – see the full text.

Contraindications

  • Known allergy to cefixime or other cephalosporins.

Important warnings

  • Hypersensitivity reactions: anaphylactic/anaphylactoid reactions including shock and fatalities; caution in penicillin-sensitive patients.
  • Clostridioides difficile-associated diarrhea, from mild diarrhea to fatal colitis, possibly also after therapy ends.
  • Dose adjustment in renal impairment and dialysis; monitor dialysis patients carefully.
  • Prothrombin activity may fall, especially in renal or hepatic impairment, poor nutrition or anticoagulant therapy.
  • Use without a proven or strongly suspected bacterial infection increases the risk of drug-resistant bacteria.

Side effects

  • Most common were gastrointestinal events (30% of adults): diarrhea 16%, loose or frequent stools 6%, nausea 7%, flatulence 4%, abdominal pain 3%, dyspepsia 3%.
  • Less common (less than 2%): pseudomembranous colitis, rash, urticaria, drug fever, pruritus, angioedema, erythema multiforme, Stevens-Johnson syndrome.
  • Transient rises in liver enzymes, hepatitis, jaundice; transient rises in BUN or creatinine, acute renal failure.

Interactions

  • Carbamazepine: elevated carbamazepine levels reported; drug monitoring may help.
  • Warfarin and anticoagulants: increased prothrombin time, with or without bleeding.
  • False-positive urine ketone tests with nitroprusside-based tests.

Pregnancy and breastfeeding

  • Observational data on cephalosporins including cefixime have not established a drug-associated risk of major birth defects, miscarriage or adverse outcomes.
  • No data on presence in human milk; cefixime is present in animal milk.

Summary of the official product information, written with AI on 2026-10-29. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

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For patients

Patient information (US)

This product has no separate US patient information.

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

Austria

  • Cefixim NectarNeclife Pt Unipessoal Lda · 1 register entry
  • SorcelifA-Med Gmbh · 2 register entries
  • TricefMerck Gesellschaft Mbh · 2 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29

Germany

  • Cefixim AlAliud Pharma Gmbh · 1 register entry
  • Cefixim AristoAristo Pharma Gmbh (Art 57) · 1 register entry
  • Cefixim HexalHexal Ag · 1 register entry
  • Cefixim NectarNeclife Pt Unipessoal Lda · 1 register entry
  • Cefixim Reiwa HealthcareReiwa Healthcare S.L · 1 register entry
  • Cefixim StadaStadapharm Gmbh · 1 register entry
  • Cefixim ViatrisViatris Germany Gmbh · 1 register entry
  • Cefixime HexalHexal Ag · 1 register entry
  • Infectoopticef SaftInfectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-10-29

Turkey

  • CefdiaİLKO İLAÇ SAN.VE TİC. A.Ş. · 2 register entries
  • CefiximaİSTANBUL İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • CephixTOPRAK İLAÇ VE KİMYEVİ MADDELER SAN.VE TİC. A.Ş. · 5 register entries
  • FixefDEVA HOLDİNG A.Ş. · 8 register entries
  • InnocefVİTALİS İLAÇ SAN. TİC. A.Ş., CELTİS İLAÇ SAN. VE TİC. A.Ş. · 6 register entries
  • MolcefNEUTEC İLAÇ SAN. TİC. A.Ş · 7 register entries
  • OlecefNEUTEC İLAÇ SAN. TİC. A.Ş · 2 register entries
  • SancefixSANDOZ İLAÇ SAN. VE TİC. A.Ş. · 3 register entries
  • SefacurCELTİS İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • SoltrexanWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 2 register entries
  • SupraxEİP ECZACIBAŞI İLAÇ PAZARLAMA A.Ş · 6 register entries
  • VitacefNUVOMED İLAÇ SAN.TİC. A.Ş. · 3 register entries
Show all 13 brand names
  • ZimaksBİLİM İLAÇ SAN. VE TİC. A.Ş. · 5 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-10-16

Brand names in 19 more European countries
Bulgaria
Cefixime Neclife, Cefixime Viatris, Cifemex, Зефацет, Неоцеф, Панцеф, Цефидант, Цефимед
Croatia
Cefiksim Alkaloid, Cefiksim Nectar
Cyprus
Cefimed, Cefixime-Synto, Cefixime Viatris, Fimecef, Tricef
Czechia
Cefixime Innfarm, Sorcelif
France
Cefixime Almus, Cefixime Arrow, Cefixime Biogaran, Cefixime Cristers, Cefixime Eg, Cefixime Evolugen, Cefixime Sandoz, Cefixime Viatris, Oroken
Greece
Ceftoral
Hungary
Cefixim Nectar, Cefixime Reiwa Healthcare, Sufixin Forte, Suprax, Xifia
Ireland
Cefixime Nectar Lifesciences, Suprax
Italy
Cefixima Aurobindo, Cefixima Doc Generici, Cefixima Eg, Cefixima Mylan, Cefixima Sandoz, Cefixoral, Drelbista, Stadium, Supracef, Unixime
Lithuania
Cefixime Medochemie
Malta
Tricef
Norway
Cefixime Frostpharma, Cefixime Medochemie
Poland
Cetix, Xifia
Portugal
Cefiton, Cefixim Nectar, Cefixima Atral, Cefixima Aurobindo, Cefixima Generis, Cefixima Germed, Cefixima Innfarm, Cefixima Medochemie, Cefixima Nectar, Cefixima Neocef, Neocef, Tricef
Romania
Axtrifia, Cefixima Sandoz, Cefiximă Medochemie, Cefiximă Stada, Eficef, Xifia
Slovakia
Cefimed, Cefixim, Cefixime Innfarm, Cefixime Medochemie, Cefixime Stada, Cefixime Viatris, Cefixím, Suprax
Slovenia
Pancef
Spain
Afixora, Cefixima Neclife, Cefixima Normon, Cefixima Reiwa Healthcare, Cefixima Sandoz, Cefixime Sandoz, Denvar
Sweden
Cefixime Frostpharma, Cefixime Medochemie

EMA – Article 57 product data (EU/EEA), 2026-10-29

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Sources

  1. U.S. Food and Drug Administration. CEFIXIME (Lupin Pharmaceuticals, Inc.) – Prescribing Information, 2025-10-14. DailyMed (NLM), 2026-10-29. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=6d68dbd9-7d75-4ff1-91db-79ff8ae879ec
  2. EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  3. EMA – Article 57 product data (EU/EEA), 2026-10-29. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-10-16. https://www.titck.gov.tr/dinamikmodul/85
  5. Wikidata (CC0): ATC J01DD.

Editorial: Medelix editorial team · last updated 2026-10-29 · How these pages are made · Report an error

Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.