Truelove and Witts criteria

Gastroenterology and hepatology

Also known as: Truelove-Witts-Kriterien · Truelove-Witts kriterleri · Truelove and Witts criteria (severity of ulcerative colitis)

What it is for

Clinical grading of the severity of an ulcerative colitis flare into mild, moderate and severe, mainly used to define acute severe ulcerative colitis.

Classification

CategoryDescription
Severe6 or more bloody stools a day plus at least one sign of systemic toxicity: temperature above 37.8 °C, pulse above 90/min, haemoglobin below 10.5 g/dL, erythrocyte sedimentation rate (ESR) above 30 mm/h, or (modified form) C-reactive protein (CRP) above 30 mg/L
Mildfewer than 4 stools a day with little or no blood and no signs of systemic toxicity
Moderatebetween mild and severe
Notethe exact limits of the mild and moderate bands differ slightly between published modified versions.

Source

Cortisone in ulcerative colitis; final report on a therapeutic trial

Br Med J 1955;2:1041–1048 (Truelove SC, Witts LJ)

DOI: 10.1136/bmj.2.4947.1041

PMID: 13260656

Edition
Truelove and Witts 1955, in the modified form in current use (C-reactive protein added)
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