SIRS criteria
Intensive care and infectious diseases
Also known as: SIRS-Kriterien · SIRS kriterleri · SIRS criteria (systemic inflammatory response syndrome)
What it is for
The systemic inflammatory response syndrome (SIRS) is present when at least TWO of the four criteria are met (ACCP/SCCM consensus, 1991/1992).
Classification
| Category | Description |
|---|---|
| Temperature | >38 °C or <36 °C |
| Heart rate | >90/min |
| Respiration | respiratory rate >20/min or arterial carbon dioxide (PaCO2) <32 mmHg (4.3 kPa) |
| White blood cells | >12,000/µL or <4,000/µL, or >10% immature (band) forms |
| Status | the older sepsis definitions (Sepsis-1 and -2) used SIRS plus infection; the Sepsis-3 task force (2016) found SIRS unhelpful for defining sepsis, which is now defined by organ dysfunction (SOFA). |
Source
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
Chest 1992;101:1644-1655 (Bone RC et al.; ACCP/SCCM Consensus Conference Committee)
PMID: 1303622
- Edition
- ACCP/SCCM consensus 1991 (published 1992); no longer part of the sepsis definition since Sepsis-3 (2016)
- Checked on
Summary of the published classification in our own words. Not a substitute for the original publication.
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