Laurén classification

Oncology, staging and radiology

Also known as: Laurén-Klassifikation (Magenkarzinom) · Laurén sınıflaması · Laurén classification of gastric adenocarcinoma

What it is for

Histological classification of gastric adenocarcinoma into two main types by gland formation and cell cohesion.

Classification

CategoryDescription
Intestinal typecohesive tumour cells forming glands, resembling intestinal (colorectal-type) adenocarcinoma.
Diffuse typepoorly cohesive cells infiltrating the wall singly or in small groups with little or no gland formation.
Indeterminatea minor group fitting neither type (Laurén's original unclassified group).
Mixedlater subdivision of the indeterminate group: both intestinal and diffuse components present.

Source

The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification

Acta Pathol Microbiol Scand 1965;64:31–49 (Laurén P)

DOI: 10.1111/apm.1965.64.1.31

PMID: 14320675

Edition
Laurén 1965; mixed category added later (Carneiro 1995); used alongside the WHO classification
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