DAS28 (Disease Activity Score 28)
Rheumatology
Also known as: DAS28 (Krankheitsaktivitäts-Score) · DAS28 (hastalık aktivite skoru) · DAS28 (Disease Activity Score in 28 joints, rheumatoid arthritis)
What it is for
Composite measure of disease activity in rheumatoid arthritis based on 28 joints (shoulders, elbows, wrists, metacarpophalangeal and proximal interphalangeal joints, knees; both sides).
Classification
| Category | Description |
|---|---|
| Components | tender joint count (TJC28, 0–28); swollen joint count (SJC28, 0–28); erythrocyte sedimentation rate (ESR, mm/h) or, in the DAS28-CRP variant, C-reactive protein; patient global assessment of disease activity (GH) on a 0–100 mm visual analogue scale. |
| Formula (DAS28-ESR) | 0.56 × √TJC28 + 0.28 × √SJC28 + 0.70 × ln(ESR) + 0.014 × GH. |
| Remission | <2.6. |
| Low disease activity | 2.6 to ≤3.2. |
| Moderate disease activity | >3.2 to ≤5.1. |
| High disease activity | >5.1. |
Source
Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis
Arthritis Rheum 1995;38:44–48 (Prevoo ML et al.)
PMID: 7818570
- Edition
- Prevoo 1995 (DAS28); activity bands per van Gestel/EULAR (current)
- Checked on
Summary of the published classification in our own words. Not a substitute for the original publication.
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