Renal sympathetic denervation 2024 in Austria: recommendations from the Austrian Society of Hypertension

ÖGH · 2024 · Austria

Source and licence

Authors
David Zweiker, Christian Koppelstätter, Katharina Hohenstein et al.
Title
Renal sympathetic denervation 2024 in Austria: recommendations from the Austrian Society of Hypertension
Journal
Wiener Klinische Wochenschrift, 2024
Licence
CC BY 4.0
Changes
Verbatim excerpts; formatting adapted

Full text retrieved 2026-10-27 from Europe PMC · PMC11420322

Licence statement of the original publication

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Recommendations

Verbatim, with grade of recommendation or strength of consensus where given.

Procedural planning and patient preparation

  • We recommend the establishment of a standard operating procedure that includes acute management in case of complications.

Abstract

Renal sympathetic denervation (RDN) is an interventional supplement to medical treatment in patients with arterial hypertension. While the first sham-controlled trial, SYMPLICITY HTN‑3 was neutral, with improved procedural details, patient selection and follow-up, recent randomized sham-controlled trials of second-generation devices show a consistent blood pressure lowering effect of RDN, as compared to sham controls. These new data and the recent U.S. Food and Drug Administration (FDA) premarket approval of two RDN devices are the basis for the present recommendations update.

This joint position paper from the Austrian Society of Hypertension, together with the Austrian Society of Nephrology and the Working Group of Interventional Cardiology from the Austrian Society of Cardiology includes an overview about the available evidence on RDN and gives specific recommendations for the work-up, patient selection, pretreatment, procedural management and follow-up in patients undergoing RDN in Austria. Specifically, RDN may be used in clinical routine care, together with lifestyle measures and antihypertensive drugs, in patients with resistant hypertension (i.e. uncontrolled blood pressure on 3 antihypertensive drugs) and in those with uncontrolled hypertension, after adequate work-up, if institutional, patient-related and procedural conditions are fulfilled.

Contents of the original publication

The section headings of the original.

  • Introduction
  • History of RDN
  • Methods of RDN
  • Safety
  • Efficacy of RDN
  • Center qualification
  • Multidisciplinary hypertension team (MDT)
  • RDN operators
  • Patient selection
  • Adherence to medical treatment
  • Screening for RDN and shared decision making
  • Resistant hypertension
  • Mild hypertension
  • Uncontrolled hypertension with intolerance to antihypertensive drugs
  • Current European Society of Hypertension guidelines
  • Predictor of response to RDN
  • When not to perform RDN
  • Procedural considerations
  • Procedural planning and patient preparation
  • Procedure
  • Follow-up and quality control
  • Conclusion

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