Practice Guidelines for Bipolar Disorder by the JSMD (Japanese Society of Mood Disorders)
Japanese Society of Mood Disorders · 2024 · Japan
Source and licence
- Authors
- Tadafumi Kato, Kazuyoshi Ogasawara, Keisuke Motomura et al.
- Title
- Practice Guidelines for Bipolar Disorder by the JSMD (Japanese Society of Mood Disorders)
- Journal
- Psychiatry and Clinical Neurosciences, 2024
- Licence
- CC BY 4.0
- Changes
- Verbatim excerpts; formatting adapted
Full text retrieved 2026-10-27 from Europe PMC · PMC11804931
Licence statement of the original publication
This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
This page reproduces excerpts of the original publication; the original is authoritative. It has not been reviewed by a physician, does not state a recommendation of Medelix and does not replace medical advice. The guideline may have been updated since.
Open the original publication →Full text on Europe PMC
Recommendations
Verbatim, with grade of recommendation or strength of consensus where given.
CQ 3–8. 1. What is an effective treatment for depressive episodes with anxiety?
- We suggest that selective serotonin reuptake inhibitors (SSRIs) be administered with caution and that benzodiazepine anxiolytics not be used in principle.
CQ 4–5. May antidepressants be used in maintenance therapy?
- We suggest that antidepressant monotherapy not be used for maintenance treatment.
Abstract
The Japanese Society of Mood Disorders (JSMD) published treatment guidelines of bipolar disorder in 2011. The present guidelines incorporating new findings were developed to comply to the guidelines of the National Academy of Medicine (NAM) by utilizing systematic reviews and meta‐analysis and taking patient and family opinions as well as insights from multiple professional fields into account. They support combination therapy using mood stabilizers and second‐generation antipsychotics in many aspects. They also have limitations, including the grouping of mood stabilizers and second‐generation antipsychotics when meta‐analysis was performed despite their distinct properties, due to the scarcity of drug‐specific evidence. Despite the limitations, these guidelines provide clinical decision support for psychiatrists in Japan.
Contents of the original publication
The section headings of the original.
- Guidelines
- Chapter 1: Characteristics of the disease
- Chapter 2: Manic Episodes
- Chapter 3: Depressive Episodes
- Chapter 4: Maintenance Therapy
- Chapter 5: Psychosocial Support
- Chapter 6: Perinatal
- Chapter 7: Side Effects and Monitoring
- Discussion
- Limitations
- Conclusion
- Supporting information
- JSMD Bipolar Disorder Guidelines Revision Working Group
- JSMD Bipolar Disorder Committee
- JSMD Guidelines Committee
- Contributor Information
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