Best practices for the management of febrile seizures in children
Italian paediatric neurology group · 2024 · Italy
Source and licence
- Authors
- Alessandro Ferretti, Antonella Riva, Alice Fabrizio et al.
- Title
- Best practices for the management of febrile seizures in children
- Journal
- Italian Journal of Pediatrics, 2024
- Licence
- CC BY 4.0
- Changes
- Verbatim excerpts; formatting adapted
Full text retrieved 2026-10-27 from Europe PMC · PMC11089695
Licence statement of the original publication
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Recommendations
We found no explicitly labelled recommendations in this publication; its recommendations are in the running text of the original.
Abstract
Febrile seizures (FS) are commonly perceived by healthcare professionals as a self-limited condition with a generally ‘benign’ nature. Nonetheless, they frequently lead to pediatric consultations, and their management can vary depending on the clinical context. For parents and caregivers, witnessing a seizure can be a distressing experience, significantly impacting their quality of life. In this review, we offer an in-depth exploration of FS management, therapeutic interventions, and prognostic factors, with the aim of providing support for physicians and enhancing communication with families. We conducted a comprehensive literature search using the PubMed and Web of Science databases, spanning the past 50 years. The search terms utilized included “febrile seizure,” “complex febrile seizure,” “simple febrile seizure,” in conjunction with “children” or “infant.” Only studies published in English or those presenting evidence-based data were included in our assessment. Additionally, we conducted a cross-reference search to identify any additional relevant data sources. Our thorough literature search resulted in a compilation of references, with carefully selected papers thoughtfully integrated into this review.
Contents of the original publication
The section headings of the original.
- Introduction
- What are febrile seizures?
- “Simple” or “complex” FS
- Management
- Diagnostic assessments
- When is hospitalization recommended?
- Red flags
- Prevention
- Vaccinations in children with FS
- Prognosis
- Mortality
- Recommendations for caregivers
- Discussion
- Conclusions
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