Child-Pugh score

Severity of chronic liver disease / cirrhosis (class A, B, C)

Sources last checked: 2026-10-13

Child-Pugh score

Severity of chronic liver disease / cirrhosis (class A, B, C)

Total bilirubin
Serum albumin
INR (or prothrombin time prolongation)
Ascites
Hepatic encephalopathy
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Pugh 1973 used prothrombin-time prolongation; the INR cut-offs are the widely used later adaptation. In primary biliary cholangitis / sclerosing cholangitis higher bilirubin cut-offs (68 / 170 µmol/L; 4 / 10 mg/dL) were proposed. Ascites and encephalopathy grading is subjective.

Source: Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973;60(8):646-649.Open

Interpretation

Class A (5–6) — well-compensatedChild-Pugh A.
Class B (7–9) — significant functional compromiseChild-Pugh B.
Class C (10–15) — decompensatedChild-Pugh C.

What is the Child-Pugh score?

The Child-Pugh score grades the severity of chronic liver disease from bilirubin, albumin, coagulation, ascites and encephalopathy into classes A, B and C. It is Pugh's 1973 modification of the Child-Turcotte classification, originally used to predict the outcome of oesophageal transection for variceal bleeding, and remains standard in hepatology and drug dosing.

When to use it

  • Staging cirrhosis at diagnosis and follow-up
  • Drug dosing: many product labels give dose adjustments by Child-Pugh class
  • Assessing operative risk and eligibility for treatments such as TIPS or HCC therapy

When not to use it

  • Transplant prioritisation — use MELD-based scores (Eurotransplant: reMELD-Na)
  • Acute liver failure, where the score was not designed

How it is calculated

CriterionPoints
Total bilirubin
< 34 µmol/L (< 2 mg/dL)1
34–50 µmol/L (2–3 mg/dL)2
> 50 µmol/L (> 3 mg/dL)3
Serum albumin
> 35 g/L (> 3.5 g/dL)1
28–35 g/L (2.8–3.5 g/dL)2
< 28 g/L (< 2.8 g/dL)3
INR (or prothrombin time prolongation)
INR < 1.7 (PT prolonged < 4 s)1
INR 1.7–2.3 (PT prolonged 4–6 s)2
INR > 2.3 (PT prolonged > 6 s)3
Ascites
None1
Mild / controlled with diuretics2
Moderate to severe / refractory3
Hepatic encephalopathy
None1
Grade 1–2 (or controlled with treatment)2
Grade 3–4 (or refractory)3

Clinical pearls and limitations

  • Pugh 1973 used prothrombin-time prolongation; the INR cut-offs are the widely used later adaptation. In primary biliary cholangitis / sclerosing cholangitis higher bilirubin cut-offs (68 / 170 µmol/L; 4 / 10 mg/dL) were proposed. Ascites and encephalopathy grading is subjective.
  • Class A 5–6, B 7–9, C 10–15 points.
  • The INR cut-offs (< 1.7, 1.7–2.3, > 2.3) replace Pugh's original prothrombin-time prolongation in seconds.
  • In cholestatic disease (PBC/PSC) higher bilirubin thresholds (68 / 170 µmol/L) were proposed.
  • Albumin can be influenced by infusions and the INR by vitamin K antagonists.

Frequently asked questions

What are the Child-Pugh classes?

Class A = 5–6 points (well-compensated), class B = 7–9 (significant functional compromise), class C = 10–15 (decompensated).

What bilirubin values are used in Child-Pugh in µmol/L?

Below 34 µmol/L scores 1, 34–50 µmol/L scores 2 and above 50 µmol/L scores 3 (about 2 and 3 mg/dL).

Child-Pugh or MELD?

Child-Pugh is used for clinical staging and drug dosing; MELD-type scores are more objective and are used for transplant allocation.

Evidence and guidelines

  1. Primary source: Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973;60(8):646-649.

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