2015 ACR/EULAR gout classification criteria

Classifies gout from clinical, laboratory and imaging findings (≥ 8 points)

Sources last checked: 2026-10-13

2015 ACR/EULAR gout classification criteria

Classifies gout from clinical, laboratory and imaging findings (≥ 8 points)

≥ 1 episode of swelling, pain or tenderness in a peripheral joint or bursa
Synovial fluid / tophus aspirate (polarising microscopy by a trained observer)
Joints/bursae involved in symptomatic episode(s) ever
Episode characteristics ever: erythema · can't bear touch/pressure · great difficulty walking or using the joint
Typical episodes (≥ 2 of: max pain < 24 h · resolution ≤ 14 days · complete resolution between episodes)
Serum urate (uricase method; highest value, ideally off urate-lowering therapy and > 4 weeks after an episode)
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Classification criteria (sensitivity 92 %, specificity 89 % in validation), not a diagnostic test — MSU crystal identification in joint or tophus aspirate remains the diagnostic reference standard. Missing imaging or synovial fluid scores 0, which lowers sensitivity.

Source: Neogi T, Jansen TL, Dalbeth N, et al. 2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 2015;74(10):1789-1798.Open

Interpretation

Criteria not applicableEntry criterion not met.
Not classified as gout (< 8 points)Not classified on the current findings. Under the criteria, MSU crystals in a symptomatic joint or bursa are sufficient on their own.
Classified as goutSufficient criterion (MSU crystals) met, or score ≥ 8.

What is the 2015 ACR/EULAR gout classification criteria?

The 2015 ACR/EULAR gout classification criteria work in three steps: an entry criterion (at least one episode of peripheral joint or bursa symptoms), a sufficient criterion (MSU crystals), and a weighted score across clinical, laboratory and imaging domains. A score of 8 or more out of 23 classifies gout. Developed by Neogi, Jansen, Dalbeth and colleagues, they reached 92 % sensitivity and 89 % specificity in validation.

When to use it

  • To classify gout for studies and registries
  • To structure the assessment when crystal identification is not available
  • To document which features support the diagnosis

When not to use it

  • Instead of joint aspiration when it is feasible — finding MSU crystals is decisive
  • In asymptomatic hyperuricaemia (entry criterion not met)

How it is calculated

Step 1 — entry: ≥ 1 episode of peripheral joint/bursa swelling, pain or tenderness. Step 2 — sufficient: MSU crystals in a symptomatic joint/bursa or tophus → gout. Step 3 — score: pattern (ankle/midfoot 1, first MTP 2) · characteristics (1/2/3) · time course (one typical episode 1, recurrent 2) · tophus 4 · serum urate (< 0.24 mmol/L −4; 0.24–< 0.36: 0; 0.36–< 0.48: 2; 0.48–< 0.60: 3; ≥ 0.60: 4) · synovial fluid MSU-negative −2 · imaging urate deposition 4 · radiographic erosion 4. Maximum 23; ≥ 8 = gout.

Clinical pearls and limitations

  • Classification criteria (sensitivity 92 %, specificity 89 % in validation), not a diagnostic test — MSU crystal identification in joint or tophus aspirate remains the diagnostic reference standard. Missing imaging or synovial fluid scores 0, which lowers sensitivity.
  • Score the highest serum urate on record, ideally off urate-lowering therapy and more than 4 weeks after a flare.
  • Two items can subtract points: urate < 0.24 mmol/L (−4) and MSU-negative synovial fluid (−2).
  • Imaging items (ultrasound double-contour sign or DECT urate; radiographic erosion) are worth 4 points each.
  • A clinical-only version without fluid or imaging was less sensitive (85 %) and specific (78 %).

Frequently asked questions

How many points classify gout?

8 or more (maximum 23), unless MSU crystals are found, which is sufficient on its own.

What serum urate unit should I use?

The criteria give both: < 0.24 mmol/L (< 4 mg/dL) −4, 0.36–< 0.48 mmol/L +2, 0.48–< 0.60 +3, ≥ 0.60 mmol/L +4.

What is the double-contour sign?

A hyperechoic irregular line over the surface of hyaline cartilage on ultrasound, independent of the insonation angle, reflecting urate deposition.

Evidence and guidelines

  1. Primary source: Neogi T, Jansen TL, Dalbeth N, et al. 2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 2015;74(10):1789-1798.
  2. Full text (open access, PMC4602275) — Table 2 and footnotes.

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