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Every clinical claim links to its source with an evidence grade. We abstain when the literature is thin instead of inventing an answer.
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Type the question the way you'd phrase it to a colleague — in your own language. A question asked in one language can still surface evidence written in another.
Search the open-access literature.
We pull from open-access clinical guidelines and peer-reviewed literature, ranking guidelines ahead of general results so the answer leans on the strongest source.
An answer, with sources you can verify.
Streamed in real time. Every claim carries a [n] citation linking back to the source, with an evidence grade. Thin evidence triggers an explicit abstention.
One question. The cited answer.
The reasoning, with the sources behind every claim. No footnotes after the fact — citations are the answer.
Does the evidence support DOACs over warfarin in older adults with atrial fibrillation?
Pooled analyses of randomised data show that direct oral anticoagulants reduce ischaemic stroke and systemic embolism compared with vitamin K antagonists in non-valvular atrial fibrillation, with a more favourable intracranial bleeding profile [1].
In the elderly subgroup specifically, a recent systematic review and meta-analysis reports that DOACs maintain or improve stroke-prevention efficacy versus warfarin while reducing intracranial haemorrhage; gastrointestinal bleeding signals vary by agent [2].
Population-level data show that growing DOAC uptake has shifted the relative incidence of stroke, intracranial haemorrhage, and gastrointestinal bleeding hospitalisations in adults with atrial fibrillation [3].
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Questions clinicians ask before they trust it.
No, by design. Medelix is an informational tool — not a regulated medical device, not clinical advice. We chose this so we can iterate fast and stay free during the research preview. The product surfaces and structures the evidence; clinical decisions stay with the clinician.
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